ES8403442A1 - Un procedimiento de preparacion de 1-2(arilmetil)aril-4-oxociclohexanol-oximas. - Google Patents

Un procedimiento de preparacion de 1-2(arilmetil)aril-4-oxociclohexanol-oximas.

Info

Publication number
ES8403442A1
ES8403442A1 ES519440A ES519440A ES8403442A1 ES 8403442 A1 ES8403442 A1 ES 8403442A1 ES 519440 A ES519440 A ES 519440A ES 519440 A ES519440 A ES 519440A ES 8403442 A1 ES8403442 A1 ES 8403442A1
Authority
ES
Spain
Prior art keywords
cyclohexenes
cyclohexanols
arylmethyl
cyclohexanes
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES519440A
Other languages
English (en)
Other versions
ES519440A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Publication of ES8403442A1 publication Critical patent/ES8403442A1/es
Publication of ES519440A0 publication Critical patent/ES519440A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE 1-2-(ARILMETIL)ARIL-4-OXOCICLOHEXANOL-OXIMAS, DE FORMULA GENERAL (I), EN LA QUE X E Y SON CADA UNO DE ELLOS, INDEPENDIENTEMENTE, HIDROGENO, ALOGENO, ALCOXI DE 1 A 2 ATOMOS DE CARBONO O ALCOHILO INFERIOR.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), EN LA QUE X E Y TIENEN EL SIGNIFICADO YA INDICADO, CON CLOROHIDRATO DE HIDROXILAMINA.DE APLICACION EN LA PREPARACION DE COMPOSICIONES FARMACEUTICAS UTILIZADAS COMO ANTIDEPRESIVOS Y ANTICONVULSIVOS.
ES519440A 1981-04-27 1983-02-01 Un procedimiento de preparacion de 1-2(arilmetil)aril-4-oxociclohexanol-oximas. Granted ES519440A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/258,097 US4313959A (en) 1981-04-27 1981-04-27 (Arylmethyl)phenyl-aminocyclohexanols, cyclohexenes and intermediates thereof

Publications (2)

Publication Number Publication Date
ES8403442A1 true ES8403442A1 (es) 1984-03-16
ES519440A0 ES519440A0 (es) 1984-03-16

Family

ID=22979083

Family Applications (2)

Application Number Title Priority Date Filing Date
ES511559A Expired ES8306705A1 (es) 1981-04-27 1982-04-21 "un procedimiento para la preparacion de (arimeltil) fenil-aminociclohexanos y -ciclohexenos".
ES519440A Granted ES519440A0 (es) 1981-04-27 1983-02-01 Un procedimiento de preparacion de 1-2(arilmetil)aril-4-oxociclohexanol-oximas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES511559A Expired ES8306705A1 (es) 1981-04-27 1982-04-21 "un procedimiento para la preparacion de (arimeltil) fenil-aminociclohexanos y -ciclohexenos".

Country Status (4)

Country Link
US (1) US4313959A (es)
EP (1) EP0063793A3 (es)
JP (1) JPS57183747A (es)
ES (2) ES8306705A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4391827A (en) * 1980-09-08 1983-07-05 Pfizer Inc. 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor
US5239110A (en) * 1992-12-30 1993-08-24 Sterling Winthrop, Inc. Phenylcyclohexanol derivatives as agents for treating CNS disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652769A (en) * 1969-10-01 1972-03-28 Merck & Co Inc Cycloalkylamines in the treatment of mental disorders involving depression and compositions therefor
GB1327691A (en) * 1970-08-31 1973-08-22 Upjohn Co Phenyl cyclohexenylamines and the preparation thereof
GB1443441A (en) * 1973-02-24 1976-07-21 Beecham Group Ltd Pharmaceutical compositions comprising diphenylpropanolamine deri vatives
US4263317A (en) * 1979-09-06 1981-04-21 Hoechst-Roussel Pharmaceuticals, Inc. Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s

Also Published As

Publication number Publication date
EP0063793A3 (en) 1983-01-19
US4313959A (en) 1982-02-02
ES519440A0 (es) 1984-03-16
ES511559A0 (es) 1983-06-01
ES8306705A1 (es) 1983-06-01
JPS57183747A (en) 1982-11-12
EP0063793A2 (en) 1982-11-03

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