ES8203087A1 - Procedimiento para la obtencion de imidazolil-indeno-tiofe- nos - Google Patents

Procedimiento para la obtencion de imidazolil-indeno-tiofe- nos

Info

Publication number
ES8203087A1
ES8203087A1 ES502033A ES502033A ES8203087A1 ES 8203087 A1 ES8203087 A1 ES 8203087A1 ES 502033 A ES502033 A ES 502033A ES 502033 A ES502033 A ES 502033A ES 8203087 A1 ES8203087 A1 ES 8203087A1
Authority
ES
Spain
Prior art keywords
imidazolyl
thiophenes
indene
medicaments
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502033A
Other languages
English (en)
Other versions
ES502033A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8203087A1 publication Critical patent/ES8203087A1/es
Publication of ES502033A0 publication Critical patent/ES502033A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE IMIDAZOLIL-INDENO-TIOFENOS. CONSISTE EN HACER REACCIONAR HALOGENO-INDENOTIOFENOS DE FORMULA GENERAL (I) CON IMIDAZOL A UNA TEMPERATURA COMPRENDIDA ENTRE 20 Y 150 C, EN PRESENCIA DE UN ACEPTOR DE ACIDO Y DE UN DILUYENTE. SE OBTIENE EL COMPUESTO (II) EN QUE R1 SIGNIFICA FENILO, R2 Y R3, JUNTO CON LOS ATOMOS DE CARBONO CON LOS QUE ESTAN ENLAZADOS, FORMAN EL RESTO TIOFENO.
ES502033A 1980-05-09 1981-05-08 Procedimiento para la obtencion de imidazolil-indeno-tiofe- nos Granted ES502033A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803017881 DE3017881A1 (de) 1980-05-09 1980-05-09 Imidazolyl-indeno-thiophene, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
ES8203087A1 true ES8203087A1 (es) 1982-03-01
ES502033A0 ES502033A0 (es) 1982-03-01

Family

ID=6102044

Family Applications (1)

Application Number Title Priority Date Filing Date
ES502033A Granted ES502033A0 (es) 1980-05-09 1981-05-08 Procedimiento para la obtencion de imidazolil-indeno-tiofe- nos

Country Status (8)

Country Link
US (1) US4349560A (es)
EP (1) EP0039814B1 (es)
JP (1) JPS574985A (es)
AT (1) ATE4714T1 (es)
AU (1) AU7013881A (es)
DE (2) DE3017881A1 (es)
ES (1) ES502033A0 (es)
FI (1) FI811409L (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605748A (en) * 1983-01-27 1986-08-12 Fmc Corporation Benzocycloalkane-thiophenemethyl compounds as intermediates
US4757082A (en) * 1984-06-18 1988-07-12 Eli Lilly And Company Method of inhibiting aromatase

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485917A (en) * 1966-04-14 1969-12-23 Janssen Pharmaceutica Nv Composition and method for combating fungus with imidazole carboxylates
CH531518A (de) * 1968-11-29 1972-12-15 Bayer Ag Verfahren zur Herstellung von N-substituierten Imidazolen und deren Salzen
DE2053080C3 (de) * 1970-10-29 1979-08-23 Bayer Ag N-substituierte Imidazole und ihre Verwendung als Arzneimittel
US4169205A (en) * 1978-10-25 1979-09-25 E. R. Squibb & Sons, Inc. Imidazole derivatives of 6,11-dihydrodibenz[b,e]oxepines and 6,11-dihydrodibenz[b,e]thiepines

Also Published As

Publication number Publication date
ATE4714T1 (de) 1983-10-15
EP0039814A3 (en) 1981-11-25
EP0039814B1 (de) 1983-09-21
AU7013881A (en) 1981-11-12
DE3160933D1 (en) 1983-10-27
JPS574985A (en) 1982-01-11
EP0039814A2 (de) 1981-11-18
FI811409L (fi) 1981-11-10
ES502033A0 (es) 1982-03-01
US4349560A (en) 1982-09-14
DE3017881A1 (de) 1981-11-12

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