ES8403124A1 - "procedimiento para preparar esteres del acido vincaminico racemicos y opticamente activos". - Google Patents
"procedimiento para preparar esteres del acido vincaminico racemicos y opticamente activos".Info
- Publication number
- ES8403124A1 ES8403124A1 ES516054A ES516054A ES8403124A1 ES 8403124 A1 ES8403124 A1 ES 8403124A1 ES 516054 A ES516054 A ES 516054A ES 516054 A ES516054 A ES 516054A ES 8403124 A1 ES8403124 A1 ES 8403124A1
- Authority
- ES
- Spain
- Prior art keywords
- acid esters
- formula
- preparation
- vincaminic
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR ESTERES DEL ACIDO VINCAMINICO RACEMICOS Y OPTICAMENTE ACTIVOS, DE FORMULA GENERAL (I), EN LA QUE R1 Y R2 REPRESENTAN, INDEPENDIENTEMENTE, ALCOHILO CON 1 A 6 ATOMOS DE CARBONO, Y SUS 14-EPIMEROS.CONSISTE EN HACER REACCIONAR UN ESTER DE OCTAHIDROINDOLO 2,3-AQUINOLINA-OXIMA, DE FORMULA GENERAL (II), EN LA QUE R1 Y R2 TIENEN EL MISMO SIGNIFICADO YA INDICADO, CON UNA SOLUCION ACUOSA DE ACIDO SULFUROSO O CON UNA SAL DEL MISMO, A UNA TEMPERATURA COMPRENDIDA ENTRE 80 Y 110 GRADOS. UNA VEZ SEPARADA LA MEZCLA 14-EPIMERICA POR METODOS CONOCIDOS, SE RESUELVEN LOS ESTERESRACEMICOS DEL ACIDO VINCAMINICO OBTENIDOS.DE APLICACION EN FARMACIA POR SER POTENTES VASODILATADORES CEREBRALES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU812812A HU182380B (en) | 1981-09-30 | 1981-09-30 | Process for producing esters of vincaminic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8403124A1 true ES8403124A1 (es) | 1984-03-01 |
| ES516054A0 ES516054A0 (es) | 1984-03-01 |
Family
ID=10961206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES516054A Granted ES516054A0 (es) | 1981-09-30 | 1982-09-29 | "procedimiento para preparar esteres del acido vincaminico racemicos y opticamente activos". |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4464534A (es) |
| JP (1) | JPS58135884A (es) |
| AT (1) | AT381311B (es) |
| BE (1) | BE894491A (es) |
| CA (1) | CA1261840A (es) |
| CH (1) | CH653334A5 (es) |
| DE (1) | DE3236144A1 (es) |
| DK (1) | DK158470C (es) |
| ES (1) | ES516054A0 (es) |
| FI (1) | FI70895C (es) |
| FR (1) | FR2513638B1 (es) |
| GB (1) | GB2110208B (es) |
| GR (1) | GR77666B (es) |
| HU (1) | HU182380B (es) |
| IL (1) | IL66891A0 (es) |
| IT (1) | IT1163005B (es) |
| NL (1) | NL8203768A (es) |
| NO (1) | NO823294L (es) |
| PL (1) | PL137648B1 (es) |
| PT (1) | PT75619B (es) |
| SE (1) | SE446534B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU182411B (en) * | 1981-11-03 | 1984-01-30 | Richter Gedeon Vegyeszet | Process for preparing eburnamonine derivatives |
| HU186891B (en) * | 1981-06-12 | 1985-10-28 | Richter Gedeon Vegyeszet | Process for producing esters of apovincaminic acid |
| HU194220B (en) * | 1985-04-19 | 1988-01-28 | Richter Gedeon Vegyeszet | Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof |
| IT1248881B (it) * | 1989-06-21 | 1995-01-30 | Richter Gedeon Vegyeszet | Derivati diesteri di ottaidro-indolo/2,3-a/tetraidropiramil/2,3-c/ chinolizina racemici ed otticamente attivi e procedimento per la loro preparazione |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3770724A (en) * | 1970-03-31 | 1973-11-06 | Roussel Uclaf | Process for preparing pentacyclic alkaloids |
| HU163143B (es) * | 1971-05-07 | 1973-06-28 | ||
| US4033969A (en) * | 1972-06-19 | 1977-07-05 | Agence Nationale De Valorisation De La Recherche (Anvar) | Vincamine derivatives |
| US4146643A (en) * | 1973-12-18 | 1979-03-27 | Sandoz Ltd. | Increasing vigilance or treating cerebral insufficiency with substituted vincamines |
| US4283401A (en) * | 1978-07-12 | 1981-08-11 | Richter Gedeon Vegyeszeti Gyar Rt | Process for the preparation of 11-bromo-vincaminic acid ester derivatives and their use in protecting animals against cerebral hypoxy |
| FR2459799A1 (fr) * | 1979-06-22 | 1981-01-16 | Synthelabo | Synthese de la ()-vincamine |
| HU181495B (en) * | 1979-05-31 | 1983-07-28 | Richter Gedeon Vegyeszet | Process for producing hydroxy-imino-eburnane derivatives |
| HU180927B (en) * | 1979-07-13 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for producing 1k-hydroximino-e-homoe-eburane de rivatives |
-
1981
- 1981-09-30 HU HU812812A patent/HU182380B/hu not_active IP Right Cessation
-
1982
- 1982-09-27 BE BE1/10595A patent/BE894491A/fr not_active IP Right Cessation
- 1982-09-28 US US06/425,866 patent/US4464534A/en not_active Expired - Fee Related
- 1982-09-29 PL PL1982238418A patent/PL137648B1/pl unknown
- 1982-09-29 DK DK431682A patent/DK158470C/da not_active IP Right Cessation
- 1982-09-29 IT IT23517/82A patent/IT1163005B/it active
- 1982-09-29 FR FR8216363A patent/FR2513638B1/fr not_active Expired
- 1982-09-29 FI FI823333A patent/FI70895C/fi not_active IP Right Cessation
- 1982-09-29 CH CH5729/82A patent/CH653334A5/de not_active IP Right Cessation
- 1982-09-29 NO NO823294A patent/NO823294L/no unknown
- 1982-09-29 GB GB08227830A patent/GB2110208B/en not_active Expired
- 1982-09-29 SE SE8205563A patent/SE446534B/sv not_active IP Right Cessation
- 1982-09-29 CA CA000412494A patent/CA1261840A/en not_active Expired
- 1982-09-29 GR GR69398A patent/GR77666B/el unknown
- 1982-09-29 AT AT0360182A patent/AT381311B/de not_active IP Right Cessation
- 1982-09-29 IL IL66891A patent/IL66891A0/xx not_active IP Right Cessation
- 1982-09-29 PT PT75619A patent/PT75619B/pt unknown
- 1982-09-29 DE DE19823236144 patent/DE3236144A1/de not_active Ceased
- 1982-09-29 ES ES516054A patent/ES516054A0/es active Granted
- 1982-09-29 NL NL8203768A patent/NL8203768A/nl not_active Application Discontinuation
- 1982-09-29 JP JP57168693A patent/JPS58135884A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| PL137648B1 (en) | 1986-07-31 |
| CA1261840A (en) | 1989-09-26 |
| JPH0348194B2 (es) | 1991-07-23 |
| GB2110208B (en) | 1985-02-20 |
| IT1163005B (it) | 1987-04-08 |
| NO823294L (no) | 1983-04-05 |
| DE3236144A1 (de) | 1983-04-07 |
| AT381311B (de) | 1986-09-25 |
| FI70895B (fi) | 1986-07-18 |
| PL238418A1 (en) | 1983-06-06 |
| HU182380B (en) | 1983-12-28 |
| ATA360182A (de) | 1986-02-15 |
| NL8203768A (nl) | 1983-04-18 |
| SE8205563L (sv) | 1983-03-31 |
| DK158470B (da) | 1990-05-21 |
| CH653334A5 (de) | 1985-12-31 |
| DK158470C (da) | 1990-10-15 |
| IL66891A0 (en) | 1982-12-31 |
| PT75619B (en) | 1985-01-08 |
| GR77666B (es) | 1984-09-25 |
| DK431682A (da) | 1983-03-31 |
| FI823333A0 (fi) | 1982-09-29 |
| BE894491A (fr) | 1983-03-28 |
| IT8223517A0 (it) | 1982-09-29 |
| SE8205563D0 (sv) | 1982-09-29 |
| FR2513638B1 (fr) | 1985-06-28 |
| FI70895C (fi) | 1986-10-27 |
| PT75619A (en) | 1982-10-01 |
| ES516054A0 (es) | 1984-03-01 |
| SE446534B (sv) | 1986-09-22 |
| FI823333L (fi) | 1983-03-31 |
| GB2110208A (en) | 1983-06-15 |
| JPS58135884A (ja) | 1983-08-12 |
| FR2513638A1 (fr) | 1983-04-01 |
| US4464534A (en) | 1984-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970519 |