ES8402822A1 - Procedimiento para la preparacion de derivados de 2-halogenopiridina - Google Patents

Procedimiento para la preparacion de derivados de 2-halogenopiridina

Info

Publication number
ES8402822A1
ES8402822A1 ES518864A ES518864A ES8402822A1 ES 8402822 A1 ES8402822 A1 ES 8402822A1 ES 518864 A ES518864 A ES 518864A ES 518864 A ES518864 A ES 518864A ES 8402822 A1 ES8402822 A1 ES 8402822A1
Authority
ES
Spain
Prior art keywords
halogen
formula
carboxylic acid
image
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518864A
Other languages
English (en)
Other versions
ES518864A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Publication of ES8402822A1 publication Critical patent/ES8402822A1/es
Publication of ES518864A0 publication Critical patent/ES518864A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 2-HALOGENOPIRIDINA DE FORMULA GENERAL (I).CONSISTE EN HACER REACCIONAR EN EXCESO LOS CORRESPONDIENTES DERIVADOS DE N-OXIDOS DE ACIDO 2-PIRIDINCARBOXILICO, DE FORMULA GENERAL (II), EN PRESENCIA DE ANHIDRIDOS ORGANICOS, ALCOHILAMINAS TERCIARIAS Y DE UN COMPUESTO SUMINISTRADOR DE HALOGENO, DE FORMULA GENERAL: CHNXM, EN LA QUE N ES 1 O 2; M ES 2 O 3; Y X ES HALOGENO. LA MEZCLA DE REACCION SE AJUSTA A UN PH COMPRENDIDO ENTRE 12 Y 13, Y A PARTIR DE ESTA MEZCLA SE AISLA EL PRODUCTO DESEADO.DE APLICACION COMOPRODUCTO INTERMEDIO PARA LA PREPARACION DE NUMEROSOS MEDICAMENTOS.
ES518864A 1982-01-14 1983-01-10 Procedimiento para la preparacion de derivados de 2-halogenopiridina Granted ES518864A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH194/82A CH658052A5 (de) 1982-01-14 1982-01-14 Verfahren zur herstellung von 2-halogenpyridinderivaten.

Publications (2)

Publication Number Publication Date
ES8402822A1 true ES8402822A1 (es) 1984-02-16
ES518864A0 ES518864A0 (es) 1984-02-16

Family

ID=4181396

Family Applications (1)

Application Number Title Priority Date Filing Date
ES518864A Granted ES518864A0 (es) 1982-01-14 1983-01-10 Procedimiento para la preparacion de derivados de 2-halogenopiridina

Country Status (10)

Country Link
US (1) US4556716A (es)
EP (1) EP0084118B1 (es)
JP (1) JPS58124768A (es)
AT (1) ATE19067T1 (es)
CA (1) CA1213893A (es)
CH (1) CH658052A5 (es)
DE (1) DE3270505D1 (es)
DK (1) DK11783A (es)
ES (1) ES518864A0 (es)
FI (1) FI76563C (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0134828B1 (de) * 1983-09-09 1989-04-05 Lonza Ag Verfahren zur Herstellung von 2-Hydroxypyridinen aus 2-Pyridincarbonsäure-N-Oxiden
US4814456A (en) * 1986-02-10 1989-03-21 The Dow Chemical Company Chlorinating waste streams to recover cyanopyridine contained therein
US4968803A (en) * 1989-04-10 1990-11-06 Allied-Signal Inc. Process for the preparation of 2-hydroxypyridine or quinoline compounds
CN106632020A (zh) * 2016-11-24 2017-05-10 山东友帮生化科技有限公司 一种2‑氨基‑5‑氯烟酸甲酯的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL302999A (es) * 1963-01-28
US3862159A (en) * 1972-02-07 1975-01-21 Microbial Chem Res Found 5-(haloalkyl) picolinic acid and derivatives
DE2252002C3 (de) * 1972-10-24 1979-08-16 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Verfahren zur Herstellung von 2-Chlorpyridin

Also Published As

Publication number Publication date
FI830007L (fi) 1983-07-15
DK11783D0 (da) 1983-01-13
FI76563B (fi) 1988-07-29
FI830007A0 (fi) 1983-01-03
EP0084118B1 (de) 1986-04-09
DE3270505D1 (en) 1986-05-15
CA1213893A (en) 1986-11-12
JPS58124768A (ja) 1983-07-25
DK11783A (da) 1983-07-15
CH658052A5 (de) 1986-10-15
FI76563C (fi) 1988-11-10
EP0084118A1 (de) 1983-07-27
ATE19067T1 (de) 1986-04-15
ES518864A0 (es) 1984-02-16
US4556716A (en) 1985-12-03

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