ES8307790A1 - Un procedimiento para preparacion de 3-(2-(4-piperidil)-1-alquiletil) indoles. - Google Patents
Un procedimiento para preparacion de 3-(2-(4-piperidil)-1-alquiletil) indoles.Info
- Publication number
- ES8307790A1 ES8307790A1 ES512473A ES512473A ES8307790A1 ES 8307790 A1 ES8307790 A1 ES 8307790A1 ES 512473 A ES512473 A ES 512473A ES 512473 A ES512473 A ES 512473A ES 8307790 A1 ES8307790 A1 ES 8307790A1
- Authority
- ES
- Spain
- Prior art keywords
- indoles
- piperidyl
- alkyl
- ethyl
- pharmaceutical preparations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 3- 2-(4-PIPERIDIL)-1-ALQUILETIL INDOLES, DE FORMULA (I), EN LA QUE X ES HIDROGENO O HALOGENO; Y R ES ALQUILO C<1<-<3. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), EN LA QUE X Y R TIENEN LOS MISMOS SIGNIFICADOS QUE EN LA FORMULA (I), CON UN HIDRURO METALICO, TAL COMO HIDRURO DE ALUMINIO Y LITIO. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO, TAL COMO UN ETER O UNA MEZCLA DE UN ETER Y UN HIDROCARBURO, A UNA TEMPERATURA COMPRENDIDA ENTRE 0 C Y LA DE EBULLICION DEL DISOLVENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTIDEPRESIVOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8110220A FR2506311A1 (fr) | 1981-05-22 | 1981-05-22 | ((piperidyl-4)-2 alkyl-1 ethyl)-3 indoles et leur utilisation comme medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES512473A0 ES512473A0 (es) | 1983-08-01 |
| ES8307790A1 true ES8307790A1 (es) | 1983-08-01 |
Family
ID=9258784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES512473A Expired ES8307790A1 (es) | 1981-05-22 | 1982-05-21 | Un procedimiento para preparacion de 3-(2-(4-piperidil)-1-alquiletil) indoles. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4416888A (es) |
| EP (1) | EP0065909B1 (es) |
| JP (1) | JPS57200384A (es) |
| AR (1) | AR231445A1 (es) |
| AU (1) | AU551047B2 (es) |
| CA (1) | CA1183137A (es) |
| DE (1) | DE3261524D1 (es) |
| DK (1) | DK220882A (es) |
| ES (1) | ES8307790A1 (es) |
| FR (1) | FR2506311A1 (es) |
| GR (1) | GR75841B (es) |
| HU (1) | HU188171B (es) |
| IL (1) | IL65474A (es) |
| MA (1) | MA19482A1 (es) |
| NO (1) | NO821699L (es) |
| PT (1) | PT74917B (es) |
| ZA (1) | ZA823492B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0429341A3 (en) * | 1989-11-20 | 1991-11-13 | Rhone-Poulenc Sante | Heterocyclic derivatives, their preparation and pharmaceuticals containing them |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB925429A (en) * | 1960-04-01 | 1963-05-08 | Irwin Neisler & Co | Indole derivatives |
| FR1289690A (fr) * | 1960-04-01 | 1962-04-06 | Irwin | Dérivés de l'indole |
| US3136770A (en) * | 1960-04-01 | 1964-06-09 | Neisler Lab Inc | Indolyl substituted piperidines |
| GB1023781A (en) * | 1962-02-01 | 1966-03-23 | Benger Lab Ltd | Substituted indoles and their preparation |
| US3445472A (en) * | 1965-12-03 | 1969-05-20 | American Home Prod | Mono- and di-aroyl pyridylethyl and piperidylethyl indoles |
| US4208417A (en) * | 1978-06-29 | 1980-06-17 | Pharmindustrie | Indole derivatives and their use as anxiolytics |
-
1981
- 1981-05-22 FR FR8110220A patent/FR2506311A1/fr active Granted
-
1982
- 1982-04-12 IL IL65474A patent/IL65474A/xx unknown
- 1982-05-03 US US06/374,365 patent/US4416888A/en not_active Expired - Fee Related
- 1982-05-04 GR GR68057A patent/GR75841B/el unknown
- 1982-05-11 EP EP82400873A patent/EP0065909B1/fr not_active Expired
- 1982-05-11 DE DE8282400873T patent/DE3261524D1/de not_active Expired
- 1982-05-17 DK DK220882A patent/DK220882A/da not_active Application Discontinuation
- 1982-05-18 PT PT74917A patent/PT74917B/pt unknown
- 1982-05-19 ZA ZA823492A patent/ZA823492B/xx unknown
- 1982-05-19 AR AR289455A patent/AR231445A1/es active
- 1982-05-20 MA MA19688A patent/MA19482A1/fr unknown
- 1982-05-21 HU HU821641A patent/HU188171B/hu unknown
- 1982-05-21 CA CA000403514A patent/CA1183137A/fr not_active Expired
- 1982-05-21 ES ES512473A patent/ES8307790A1/es not_active Expired
- 1982-05-21 JP JP57086382A patent/JPS57200384A/ja active Pending
- 1982-05-21 NO NO821699A patent/NO821699L/no unknown
- 1982-05-21 AU AU84043/82A patent/AU551047B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU8404382A (en) | 1982-11-25 |
| EP0065909A1 (fr) | 1982-12-01 |
| DK220882A (da) | 1982-11-23 |
| ZA823492B (en) | 1983-03-30 |
| IL65474A (en) | 1985-08-30 |
| CA1183137A (fr) | 1985-02-26 |
| ES512473A0 (es) | 1983-08-01 |
| MA19482A1 (fr) | 1982-12-31 |
| AU551047B2 (en) | 1986-04-17 |
| PT74917A (fr) | 1982-06-01 |
| JPS57200384A (en) | 1982-12-08 |
| DE3261524D1 (en) | 1985-01-24 |
| HU188171B (en) | 1986-03-28 |
| FR2506311A1 (fr) | 1982-11-26 |
| EP0065909B1 (fr) | 1984-12-12 |
| GR75841B (es) | 1984-08-02 |
| AR231445A1 (es) | 1984-11-30 |
| PT74917B (fr) | 1983-12-07 |
| NO821699L (no) | 1982-11-23 |
| IL65474A0 (en) | 1982-07-30 |
| US4416888A (en) | 1983-11-22 |
| FR2506311B1 (es) | 1983-12-16 |
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