ES8305690A1 - Procedimiento para la obtencion de derivados del 3-amino-1,2-propandiol. - Google Patents

Procedimiento para la obtencion de derivados del 3-amino-1,2-propandiol.

Info

Publication number
ES8305690A1
ES8305690A1 ES514366A ES514366A ES8305690A1 ES 8305690 A1 ES8305690 A1 ES 8305690A1 ES 514366 A ES514366 A ES 514366A ES 514366 A ES514366 A ES 514366A ES 8305690 A1 ES8305690 A1 ES 8305690A1
Authority
ES
Spain
Prior art keywords
derivatives
amino
formula
image
propane diol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514366A
Other languages
English (en)
Other versions
ES514366A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES514366A0 publication Critical patent/ES514366A0/es
Publication of ES8305690A1 publication Critical patent/ES8305690A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/201,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22Radicals substituted by singly bound oxygen or sulfur atoms etherified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DEL 3-AMINO-1,2-PROPANDIOL, DE FORMULA (I), EN LA QUE R PUEDE SER UNO DE VARIOS RADICALES; Y ALK ES UN RADICAL -CH -CH O CH -CH-CH -. CONSISTE EN LA REACCION DE REDUCCION DEL GRUPO R DE UN COMPUESTO DE FORMULA (II), EN LA QUE R ES UN GRUPO REDUCIBLE DE FORMULA -CH=N-ALK O -CH -N=ALK , SIENDO ALK Q UN RESTO ALQUILENO CORRESPONDIENTE A ALK; X ES HIDROGENO O UN RADICAL SUSTITUIBLE POR HIDROGENO; Y R TIENE EL MISMO SIGNIFICADO QUE R O ES ALQUILO INFERIOR-SULFONILAMINO; Y SIMULTANEAMENTE SE SUSTITUYE EL RADICAL X POR HIDROGENO. LA REDUCCION SE EFECTUA CON HIDROGENO ACTIVADO CATALITICAMENTE, O CON UN HIDRURO DE METAL ALCALINO-BORO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE IRREGULARIDADES EN EL RITMO CARDIACO, ANGINA DE PECHO Y DE LA HIPERTONIA.
ES514366A 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1,2-propandiol. Expired ES8305690A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH611880 1980-08-13

Publications (2)

Publication Number Publication Date
ES514366A0 ES514366A0 (es) 1983-05-01
ES8305690A1 true ES8305690A1 (es) 1983-05-01

Family

ID=4304561

Family Applications (8)

Application Number Title Priority Date Filing Date
ES504682A Expired ES8301462A1 (es) 1980-08-13 1981-08-11 Procedimiento para la obtencion de derivados del 3-amino-1,2propandiol
ES514371A Expired ES8305694A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, s-propandiol
ES514365A Expired ES8305689A1 (es) 1980-08-13 1982-07-26 Procedimiento para obtencion de derivados del 3-amino-1,2- propandiol.
ES514368A Granted ES514368A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514370A Granted ES514370A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1 2-propandiol
ES514369A Expired ES8305693A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514367A Granted ES514367A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514366A Expired ES8305690A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1,2-propandiol.

Family Applications Before (7)

Application Number Title Priority Date Filing Date
ES504682A Expired ES8301462A1 (es) 1980-08-13 1981-08-11 Procedimiento para la obtencion de derivados del 3-amino-1,2propandiol
ES514371A Expired ES8305694A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, s-propandiol
ES514365A Expired ES8305689A1 (es) 1980-08-13 1982-07-26 Procedimiento para obtencion de derivados del 3-amino-1,2- propandiol.
ES514368A Granted ES514368A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514370A Granted ES514370A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1 2-propandiol
ES514369A Expired ES8305693A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514367A Granted ES514367A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol

Country Status (17)

Country Link
EP (1) EP0045964A1 (es)
JP (1) JPS5759842A (es)
KR (1) KR840002266B1 (es)
AR (6) AR231273A1 (es)
AU (1) AU543647B2 (es)
CA (1) CA1192221A (es)
DD (3) DD202691A5 (es)
DK (1) DK358381A (es)
ES (8) ES8301462A1 (es)
FI (1) FI812465L (es)
GR (1) GR74992B (es)
HU (1) HU186342B (es)
IL (1) IL63539A (es)
NO (1) NO812736L (es)
NZ (1) NZ198020A (es)
PT (1) PT73511B (es)
ZA (1) ZA815554B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58417B1 (en) * 1984-04-27 1993-09-22 Ici Plc Chemical derivatives
GB201101959D0 (en) * 2011-02-04 2011-03-23 Univ Nottingham Novel ether linked compoundsand improved treatments for cardiac and cardiovascular disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1398738A (en) * 1972-12-05 1975-06-25 Pfizer Ltd Propanolamine derivatives
DD144050A5 (de) * 1978-06-05 1980-09-24 Ciba Geigy Ag Verfahren zur herstellung von n-alkylierten aminoalkoholen
DD150456A5 (de) * 1979-03-01 1981-09-02 Ciba Geigy Ag Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols

Also Published As

Publication number Publication date
AR231278A1 (es) 1984-10-31
DD202691A5 (de) 1983-09-28
ES514369A0 (es) 1983-05-01
ES504682A0 (es) 1982-12-01
IL63539A0 (en) 1981-11-30
ES514366A0 (es) 1983-05-01
DD202532A5 (de) 1983-09-21
ES514365A0 (es) 1983-04-16
ES8305692A1 (es) 1983-05-01
ES8306473A1 (es) 1983-06-01
KR830006173A (ko) 1983-09-17
FI812465L (fi) 1982-02-14
AU543647B2 (en) 1985-04-26
ES514371A0 (es) 1983-05-01
EP0045964A1 (de) 1982-02-17
AR231631A1 (es) 1985-01-31
AR231274A1 (es) 1984-10-31
DK358381A (da) 1982-02-14
GR74992B (es) 1984-07-12
AU7402081A (en) 1982-02-18
DD202286A5 (de) 1983-09-07
ES8305691A1 (es) 1983-04-16
ES8305689A1 (es) 1983-04-16
KR840002266B1 (ko) 1984-12-14
ES514367A0 (es) 1983-04-16
PT73511A (en) 1981-09-01
HU186342B (en) 1985-07-29
NZ198020A (en) 1985-04-30
ES514368A0 (es) 1983-05-01
ES8305693A1 (es) 1983-05-01
AR231275A1 (es) 1984-10-31
AR229188A1 (es) 1983-06-30
PT73511B (en) 1983-07-06
AR231273A1 (es) 1984-10-31
NO812736L (no) 1982-02-15
ES8305694A1 (es) 1983-05-01
ES514370A0 (es) 1983-06-01
IL63539A (en) 1984-11-30
JPS5759842A (en) 1982-04-10
CA1192221A (en) 1985-08-20
ES8301462A1 (es) 1982-12-01
ZA815554B (en) 1982-08-25

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19860217