ES8302099A1 - "procedimiento para la determinacion optica del comportamiento de coagulacion de la sangre". - Google Patents

"procedimiento para la determinacion optica del comportamiento de coagulacion de la sangre".

Info

Publication number
ES8302099A1
ES8302099A1 ES510226A ES510226A ES8302099A1 ES 8302099 A1 ES8302099 A1 ES 8302099A1 ES 510226 A ES510226 A ES 510226A ES 510226 A ES510226 A ES 510226A ES 8302099 A1 ES8302099 A1 ES 8302099A1
Authority
ES
Spain
Prior art keywords
reagent
optical determination
blood clotting
clotting reaction
thromboplastin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES510226A
Other languages
English (en)
Other versions
ES510226A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES510226A0 publication Critical patent/ES510226A0/es
Publication of ES8302099A1 publication Critical patent/ES8302099A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

PROCEDIMIENTO PARA LA DETERMINACION OPTICA DEL COMPORTAMIENTO DE COAGULACION DE LA SANGRE (ENSAYO DE QUICK). CONSISTE EN AÑADIR, AL LIQUIDO A INVESTIGAR, UNA TROMBOPLASTINA NO ACTIVA PROTEOLITICAMENTE, UN SUBSTRATO SINTETICO DE TROMBINA Y UN TAMPON; Y MEDIR EL TIEMPO DE COAGULACION POR OBSERVACION OPTICA DEL FRAGMENTO PUESTO EN LIBERTAD. LA TROMBOPLASTINA SE OBTIENE POR INCUBACION DE UN POLVO SECO A BASE DE CEREBRO EN UNA DISOLUCION ACUOSA NEUTRA CON ACETONA A 25<025>C A 40<025>C SEPARACION DEL INSOLUBLE, TRATAMIENTO CON UN TENSIOACTIVO EN PRESENCIA DE FORMIATO, Y SECADO DE LA FRACCION SOLUBLE SEPARADA. ESTE ENSAYO TIENE APLICACIONES PARA INVESTIGACION PREOPERATORIA, VIGILANCIA DE LA TERAPIA CON ANTICOAGULANTES Y PARA CONTROL DE DESARROLLO DE NUMEROSAS ENFERMEDADES.
ES510226A 1981-04-02 1982-03-08 "procedimiento para la determinacion optica del comportamiento de coagulacion de la sangre". Expired ES8302099A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3113350A DE3113350A1 (de) 1981-04-02 1981-04-02 Reagens zur optischen bestimmung des blutgerinnungsverhaltens

Publications (2)

Publication Number Publication Date
ES510226A0 ES510226A0 (es) 1983-02-01
ES8302099A1 true ES8302099A1 (es) 1983-02-01

Family

ID=6129170

Family Applications (1)

Application Number Title Priority Date Filing Date
ES510226A Expired ES8302099A1 (es) 1981-04-02 1982-03-08 "procedimiento para la determinacion optica del comportamiento de coagulacion de la sangre".

Country Status (10)

Country Link
US (1) US4458015A (es)
EP (1) EP0062310B1 (es)
JP (1) JPS57178161A (es)
AT (1) ATE16944T1 (es)
CA (1) CA1198660A (es)
DD (1) DD202347A5 (es)
DE (2) DE3113350A1 (es)
DK (1) DK157939C (es)
ES (1) ES8302099A1 (es)
NO (1) NO161079C (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004426A1 (en) * 1984-03-26 1985-10-10 International Health Services A method of determining the clotting time of blood and particulate reagents therefor
DE3413311A1 (de) * 1984-04-09 1985-10-17 Behringwerke Ag, 3550 Marburg Reagenz zur bestimmung der thromboplastinzeit
US4755461A (en) * 1986-04-17 1988-07-05 Bio/Data Corporation Tableted blood plasma microconcentrated thromboplastin coagulation reagent
US6261792B1 (en) 1990-12-07 2001-07-17 The Liposome Company, Inc. Lipid-dependent diagnostic assays
JP3180824B2 (ja) * 1991-08-30 2001-06-25 シスメックス株式会社 血液凝固試薬
ES2151509T3 (es) * 1992-04-27 2001-01-01 Avocet Medical Inc Articulo de prueba y metodo para llevar a cabo ensayos de coagulacion de la sangre.
US5580744A (en) * 1992-04-27 1996-12-03 Avocet Medical, Inc. Test article and method for performing blood coagulation assays
US5358853A (en) * 1992-08-03 1994-10-25 Akzo Av Liquid thromboplastin reagent
ATE398775T1 (de) 2001-05-09 2008-07-15 Axis Shield Asa Testvorrichtung
DE102008030942A1 (de) 2008-07-02 2010-01-07 Christoph Miethke Gmbh & Co Kg Hirnwasserdrainagen
HUP1300542A2 (hu) * 2013-09-19 2015-03-30 Diagon Kft Eljárás és mérõrendszer véralvadási jellemzõk meghatározására
WO2021019529A1 (en) * 2019-07-31 2021-02-04 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods and kits for identifying thrombus origin and optimizing post-ischemic event treatment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3183159A (en) * 1962-03-20 1965-05-11 Ortho Pharma Corp Stabilized partial thromboplastin reagent
US3228841A (en) * 1965-06-10 1966-01-11 Warner Lambert Pharmaceutical Diagnostic reagent composition for determining blood coagulation factors and method of use
CH622286A5 (es) * 1975-06-23 1981-03-31 Pentapharm Ag
US4169015A (en) * 1975-07-11 1979-09-25 Ab Kabi Novel chromogenic thrombin substrates
US4289498A (en) * 1979-01-08 1981-09-15 Ortho Diagnostics, Inc. One-stage prothrombin assay and compositions useful therein

Also Published As

Publication number Publication date
NO161079B (no) 1989-03-20
DK157939C (da) 1990-08-27
DK157939B (da) 1990-03-05
DE3267870D1 (en) 1986-01-23
DE3113350A1 (de) 1982-10-21
EP0062310A1 (de) 1982-10-13
CA1198660A (en) 1985-12-31
JPS57178161A (en) 1982-11-02
JPS6356501B2 (es) 1988-11-08
DK151982A (da) 1982-10-03
ES510226A0 (es) 1983-02-01
NO161079C (no) 1989-06-28
DD202347A5 (de) 1983-09-07
NO821101L (no) 1982-10-04
ATE16944T1 (de) 1985-12-15
US4458015A (en) 1984-07-03
EP0062310B1 (de) 1985-12-11

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