ES8201530A1 - Procedimiento de preparar cicloalquil propanol aminas - Google Patents

Procedimiento de preparar cicloalquil propanol aminas

Info

Publication number
ES8201530A1
ES8201530A1 ES500978A ES500978A ES8201530A1 ES 8201530 A1 ES8201530 A1 ES 8201530A1 ES 500978 A ES500978 A ES 500978A ES 500978 A ES500978 A ES 500978A ES 8201530 A1 ES8201530 A1 ES 8201530A1
Authority
ES
Spain
Prior art keywords
formula
radical
alkyl
preparation
see diagramm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES500978A
Other languages
English (en)
Other versions
ES500978A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre SA
Original Assignee
Pierre Fabre SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre SA filed Critical Pierre Fabre SA
Publication of ES8201530A1 publication Critical patent/ES8201530A1/es
Publication of ES500978A0 publication Critical patent/ES500978A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE CICLOALQUIL PROPANOLAMINAS DE FORMULA (I), ASI COMO DE SUS SALES DE ACIDOS FISIOLOGICAMENTE COMPATIBLES, FORMULA EN LA QUE A ES UN RADICAL CICLICO CARBONADO NO AROMATICO; R1 ES RADICAL ALQUILO O ACILO; R2 ES HIDROGENO O UN RADICAL ALQUILO; B ES METILENO; M VALE 0-2; Y R PUEDE SER VARIOS RADICALES. CONSISTE EN LA REACCION DE UN EPOXIDO DE FORMULA (II) CON UNA AMINA DE FORMULA R-NH2, EN LAS QUE R1, R2, R, A, B Y M TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN METANOL A TEMPERATURA AMBIENTE. EL EPOXIDO DE FORMULA (II) SE OBTIENE POR REACCION DE EPICLORHIDRINA CON UN ALCOHOL DE FORMULA (III) EN PRESENCIA DE HIDROXIDO SODICO Y DE UN COMPUESTO DE AMONIO CUATERNARIO COMO CATALIZADOR.
ES500978A 1980-04-04 1981-04-01 Procedimiento de preparar cicloalquil propanol aminas Granted ES500978A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8007718A FR2479812A1 (fr) 1980-04-04 1980-04-04 Cycloalcoyl propanol amines utiles comme medicaments et procede pour leur preparation

Publications (2)

Publication Number Publication Date
ES8201530A1 true ES8201530A1 (es) 1982-01-01
ES500978A0 ES500978A0 (es) 1982-01-01

Family

ID=9240575

Family Applications (1)

Application Number Title Priority Date Filing Date
ES500978A Granted ES500978A0 (es) 1980-04-04 1981-04-01 Procedimiento de preparar cicloalquil propanol aminas

Country Status (5)

Country Link
EP (1) EP0037777B1 (es)
AT (1) ATE4800T1 (es)
DE (1) DE3161007D1 (es)
ES (1) ES500978A0 (es)
FR (1) FR2479812A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521856A1 (fr) * 1982-02-19 1983-08-26 Pos Lab Medicament ophtalmique pour le traitement des glaucomes, a base d'ethers-oxydes ou d'ether-oximes de derives alcoylamines
DE3704604A1 (de) * 1987-02-13 1988-08-25 Mack Chem Pharm Oximether von 2,6-dioxabicyclo(3.3.0)octanonen, herstellungsverfahren und anwendung als arzneimittel
IL156386A0 (en) * 2000-12-21 2004-01-04 Alcoa Inc Aluminum alloy products and artificial aging method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE837320A (fr) * 1976-01-06 1976-05-03 Derives ethers de 3-amino-1,2-propanodiol

Also Published As

Publication number Publication date
FR2479812B1 (es) 1984-02-03
FR2479812A1 (fr) 1981-10-09
ES500978A0 (es) 1982-01-01
ATE4800T1 (de) 1983-10-15
EP0037777B1 (fr) 1983-09-28
EP0037777A1 (fr) 1981-10-14
DE3161007D1 (en) 1983-11-03

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