ES8201316A1 - Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides - Google Patents

Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides

Info

Publication number
ES8201316A1
ES8201316A1 ES80498048A ES498048A ES8201316A1 ES 8201316 A1 ES8201316 A1 ES 8201316A1 ES 80498048 A ES80498048 A ES 80498048A ES 498048 A ES498048 A ES 498048A ES 8201316 A1 ES8201316 A1 ES 8201316A1
Authority
ES
Spain
Prior art keywords
biologically active
lipoid
preparing
active particles
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES80498048A
Other languages
English (en)
Other versions
ES498048A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HUMAN OLTOANYAGTERMELO
Original Assignee
HUMAN OLTOANYAGTERMELO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HUMAN OLTOANYAGTERMELO filed Critical HUMAN OLTOANYAGTERMELO
Publication of ES498048A0 publication Critical patent/ES498048A0/es
Publication of ES8201316A1 publication Critical patent/ES8201316A1/es
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/586—Liposomes, microcapsules or cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

PROCEDIMIENTO DE PREPARAR AGENTES DE UTILIDAD CLINICA A PARTIR DE SUSTANCIAS SOLUBLES EN LIPOIDES. SE MEZCLA UNA SUSTANCI FORMADORA DE PARTICULAS DE LIPOIDES QUE CONTIENE UN AGENTE DE ACTIVIDAD SUPERFICIAL DISUELTO EN ALCOHOL, O CUALQUIER OTRO DISOLVENTE ORGANICO, CON UNA DISOLUCION DE UNA SUSTANCIA BIOLOGICAMENTE ACTIVA EN AGUA O UNA DISOLUCION CON UN PH DE 2 A 10, EN UNA RELACION DE VOLUMEN DE 1: 1000 A 9: 1, AGITANDO LA MEZCLA DE REACCION DURANTE UN MINUTO, AL MENOS, Y DEJANDOLO REPOSAR DURANTE SIETE DIAS, PARA LUEGO SEPARAR LAS PARTICULAS PRECIPITADAS. TAMBIEN SE PUEDE MEZCLAR CON UNA SOLUCION ELECTROLITICA ACUOSA, SEPARANDO LAS PARTICULAS PRECIPITADAS Y SUSPENDERLAS EN AGUA O EN UNA DISOLUCION ELECTROLITICA ACUOSA CON AGITACION O SIN ELLA. SE UTILIZA PARA PREPARAR SISTEMAS PARA EXAMENES DE INMUNODIAGNOSIS <IN VITRO>, COMO DIAGNOSTICO DE UNA DETERMINACION CUANTITATIVA DE ARTRITIS REUMATOIDE.
ES80498048A 1979-12-27 1980-12-22 Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides Expired ES8201316A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79HU299A HU184141B (en) 1979-12-27 1979-12-27 Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof

Publications (2)

Publication Number Publication Date
ES498048A0 ES498048A0 (es) 1981-12-16
ES8201316A1 true ES8201316A1 (es) 1981-12-16

Family

ID=10997378

Family Applications (1)

Application Number Title Priority Date Filing Date
ES80498048A Expired ES8201316A1 (es) 1979-12-27 1980-12-22 Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides

Country Status (21)

Country Link
US (1) US4396630A (es)
JP (1) JPS57112334A (es)
BE (1) BE886884A (es)
CA (1) CA1165237A (es)
CH (1) CH655246A5 (es)
CS (1) CS241478B2 (es)
DD (1) DD158738A5 (es)
DE (1) DE3048815A1 (es)
DK (1) DK160288C (es)
ES (1) ES8201316A1 (es)
FR (1) FR2472386B1 (es)
GB (1) GB2066203B (es)
HU (1) HU184141B (es)
IT (1) IT1150073B (es)
NL (1) NL8007041A (es)
PL (1) PL228755A1 (es)
PT (1) PT72261B (es)
RO (1) RO81371A (es)
SE (1) SE453537B (es)
SU (1) SU1487802A3 (es)
YU (1) YU44413B (es)

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US4806466A (en) * 1981-10-29 1989-02-21 The Regents Of The University Of California Cell agglutination reagent comprising conjugates of antibody covalently bound to liposomes
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
DD247570A3 (de) * 1983-01-14 1987-07-15 Univ Berlin Humboldt Vesikulaeres trenn-, fuell- und traegermaterial
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
US4708861A (en) * 1984-02-15 1987-11-24 The Liposome Company, Inc. Liposome-gel compositions
US5916588A (en) * 1984-04-12 1999-06-29 The Liposome Company, Inc. Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
US6090406A (en) * 1984-04-12 2000-07-18 The Liposome Company, Inc. Potentiation of immune responses with liposomal adjuvants
GB2160312B (en) * 1984-04-13 1987-09-16 South African Inventions Adjuvant for immunisation
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
US4619904A (en) * 1984-10-29 1986-10-28 General Electric Company Agglutinating immunoassay using protein-coated liquid droplets
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
JP2519029B2 (ja) * 1985-10-31 1996-07-31 ケ−・ブイ・ファ−マシュ−ティカル・カンパニ− 腟内送達用製剤
US5266329A (en) * 1985-10-31 1993-11-30 Kv Pharmaceutical Company Vaginal delivery system
US4790987A (en) * 1985-11-15 1988-12-13 Research Corporation Viral glycoprotein subunit vaccine
CA1338736C (fr) * 1986-12-05 1996-11-26 Roger Baurain Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation
US5688519A (en) * 1987-04-06 1997-11-18 Leonard; Robert J. Flash-flow fused medicinal implants
US4748024A (en) * 1987-04-06 1988-05-31 Endocon, Inc. Flash flow fused medicinal implants
WO1990001948A1 (en) * 1988-08-25 1990-03-08 The Liposome Company, Inc. Influenza vaccine and novel adjuvants
EP0374296B1 (en) * 1988-12-22 1995-02-01 Dade International Inc. Lipohaptens and use of carrier-bound lipohaptens in immunoassays
US5100662A (en) * 1989-08-23 1992-03-31 The Liposome Company, Inc. Steroidal liposomes exhibiting enhanced stability
JPH07113641B2 (ja) * 1989-11-17 1995-12-06 積水化学工業株式会社 梅毒診断試薬の製造方法
NL9000207A (es) * 1990-01-29 1991-08-16 Duphar Int Res
DE69131709T2 (de) * 1990-06-29 2000-05-25 Chiron Corp Liposomen enthaltende impfstoffzusammensetzungen
US5709879A (en) * 1990-06-29 1998-01-20 Chiron Corporation Vaccine compositions containing liposomes
IE912535A1 (en) * 1990-07-27 1992-01-29 Res Dev Foundation Liposomes that Provide Thymic Dependent Help to Weak Vaccine¹Antigens
WO1992004887A1 (en) * 1990-09-25 1992-04-02 Kyowa Hakko Kogyo Co., Ltd. Induction of cytotoxic t cell
US6048531A (en) * 1991-04-15 2000-04-11 Albany Medical College Immunogenic composites capable of stimulating production of anti-peptide antibodies, pharmaceutical compositions employing these composites and methods of selectively inducing production of anti-peptide antibodies
US5336507A (en) * 1992-12-11 1994-08-09 Sterling Winthrop Inc. Use of charged phospholipids to reduce nanoparticle aggregation
GB9320668D0 (en) * 1993-10-07 1993-11-24 Secr Defence Liposomes containing particulare materials
AUPM500494A0 (en) * 1994-04-12 1994-05-05 Minister For Agriculture & Rural Affairs For The State Of New South Wales, The Composition for use in increasing mucosal immunity
PL363618A1 (en) * 2000-11-09 2004-11-29 Neopharm, Inc. Sn-38 lipid complexes and methods of use
WO2003030864A1 (en) * 2001-05-29 2003-04-17 Neopharm, Inc. Liposomal formulation of irinotecan
AU2003225689B2 (en) * 2002-03-05 2009-03-26 Transave, Inc. Methods for entrapment of bioactive agent in a liposome or lipid complex
AU2003296897A1 (en) * 2002-08-20 2004-05-04 Neopharm, Inc. Pharmaceutical formulations of camptothecine derivatives
US20060030578A1 (en) * 2002-08-20 2006-02-09 Neopharm, Inc. Pharmaceutically active lipid based formulation of irinotecan
PT1581236E (pt) * 2002-10-29 2013-12-24 Insmed Inc Libertação prolongada de anti-infecciosos
US7718189B2 (en) * 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
US7879351B2 (en) * 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
KR100651728B1 (ko) * 2004-11-10 2006-12-06 한국전자통신연구원 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법
JP5114628B2 (ja) * 2005-02-25 2013-01-09 国立大学法人三重大学 リポソームワクチンの作製法
EP3067046B1 (en) * 2005-12-08 2020-03-25 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections
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US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
SI2852391T1 (sl) 2012-05-21 2022-04-29 Insmed Incorporated Sistemi za obravnavo pljučnih infekcij
CA2891487A1 (en) 2012-11-29 2014-06-05 Insmed Incorporated Stabilized vancomycin formulations
DK3466432T3 (da) 2014-05-15 2020-09-28 Insmed Inc Fremgangsmåder til behandling af pulmonale non-tuberkuløse mykobakterielle infektioner
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US3265629A (en) * 1958-12-22 1966-08-09 Ncr Co Coating by phase separation
DE2249552A1 (de) * 1971-10-12 1973-05-30 Inchema S A Verfahren zur inkapsulation von insbesondere wasserloeslichen verbindungen
GB1502774A (en) * 1974-06-25 1978-03-01 Nat Res Dev Immunological preparations
JPS5126213A (ja) * 1974-08-21 1976-03-04 Tanabe Seiyaku Co Johoseibiryushiseizaino seiho
GB1564500A (en) * 1975-09-29 1980-04-10 Wellcome Found Biological preparations
GB1523965A (en) * 1976-03-19 1978-09-06 Ici Ltd Pharmaceutical compositions containing steroids
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
IT1110989B (it) * 1979-01-19 1986-01-13 Erba Farmitalia Forme farmaceutiche costitutite da liposomi e procedimenti relativi
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
JPS55118415A (en) * 1979-02-28 1980-09-11 Pii Papahadojiyopo Dometoriosu Method of encapsulating biologically active substance in lipoid cell

Also Published As

Publication number Publication date
SU1487802A3 (ru) 1989-06-15
GB2066203B (en) 1984-01-11
ES498048A0 (es) 1981-12-16
JPS57112334A (en) 1982-07-13
HU184141B (en) 1984-07-30
CA1165237A (en) 1984-04-10
US4396630A (en) 1983-08-02
PT72261A (en) 1981-01-01
JPH0314814B2 (es) 1991-02-27
DK160288B (da) 1991-02-25
YU44413B (en) 1990-08-31
CH655246A5 (de) 1986-04-15
CS241478B2 (en) 1986-03-13
DE3048815A1 (de) 1981-09-10
FR2472386B1 (es) 1985-08-23
NL8007041A (nl) 1981-07-16
GB2066203A (en) 1981-07-08
SE453537B (sv) 1988-02-08
YU329080A (en) 1984-04-30
RO81371A (ro) 1984-04-02
DK552280A (da) 1981-06-28
DD158738A5 (de) 1983-02-02
IT1150073B (it) 1986-12-10
DK160288C (da) 1991-08-05
BE886884A (fr) 1981-06-29
IT8026950A0 (it) 1980-12-24
FR2472386A1 (es) 1981-07-03
CS924680A2 (en) 1985-07-16
PT72261B (en) 1981-11-05
RO81371B (ro) 1983-11-02
SE8009068L (sv) 1981-06-28
PL228755A1 (es) 1982-02-15

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