ES8201120A1 - Procedimiento de preparacion de eteres basicos de 4-hidro- xi-benzofenonas - Google Patents
Procedimiento de preparacion de eteres basicos de 4-hidro- xi-benzofenonasInfo
- Publication number
- ES8201120A1 ES8201120A1 ES498846A ES498846A ES8201120A1 ES 8201120 A1 ES8201120 A1 ES 8201120A1 ES 498846 A ES498846 A ES 498846A ES 498846 A ES498846 A ES 498846A ES 8201120 A1 ES8201120 A1 ES 8201120A1
- Authority
- ES
- Spain
- Prior art keywords
- benzophenones
- hydroxy
- beta
- acting
- blocking agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Epoxy Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ETERES BASSICOS DE 4-HIDROXI-BENZOFENONAS, DE FORMULA (I), EN LA QUE R ES HIDROGENO O CLORO, Y R ES HIDROGENO O EL RADICAL COCH3. SE HACE REACCIONAR UNA 4-HIDROXI-BENZOFENONA DE FORMULA (II), EN LA QUE R Y R'' SON LOS MISMOS QUE EN LA FORMULA (I), CON EPICLORHIDRINA, EN ALCOHOL ANHIDRO Y EN PRESENCIA DE METOXIDO SODICO Y DEMETILFORMAMIDA, A UNOS 100 C, EL PRODUCTO RESULTANTE SE HACE REACCIONAR CON ISIPROPILAMINA EN ALCOHOL A UNA TEMPERATURA COMPRENDIDA ENTRE 35-40 C. EL COMPUESTO OBTENIDO SE SEPARA Y PURIFICA POR METODOS CONVENCIONALES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD BETABLOQUEADORA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT19887/80A IT1147311B (it) | 1980-02-13 | 1980-02-13 | Eteri basici di 4-idrossi-benzofenoni con attivita' quali agenti betabloccanti e relativi procedimento di preparazione |
Publications (2)
Publication Number | Publication Date |
---|---|
ES498846A0 ES498846A0 (es) | 1981-12-01 |
ES8201120A1 true ES8201120A1 (es) | 1981-12-01 |
Family
ID=11162071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES498846A Expired ES8201120A1 (es) | 1980-02-13 | 1981-01-27 | Procedimiento de preparacion de eteres basicos de 4-hidro- xi-benzofenonas |
Country Status (10)
Country | Link |
---|---|
US (1) | US4376788A (es) |
JP (1) | JPS6026381B2 (es) |
AT (1) | AT374450B (es) |
CA (1) | CA1138897A (es) |
DE (1) | DE3104785A1 (es) |
ES (1) | ES8201120A1 (es) |
FR (1) | FR2475540A1 (es) |
GB (1) | GB2068963B (es) |
IT (1) | IT1147311B (es) |
ZA (1) | ZA81946B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63208911A (ja) * | 1987-02-26 | 1988-08-30 | Atsugi Motor Parts Co Ltd | 圧力制御弁 |
WO2011012560A1 (en) | 2009-07-30 | 2011-02-03 | Basf Se | Macrophotoinitiators |
RU2572839C2 (ru) | 2010-02-23 | 2016-01-20 | Колопласт А/С | Полимерные фотоинициаторы |
SG186780A1 (en) | 2010-06-22 | 2013-02-28 | Coloplast As | Hydrophilic gels from polyalkylether-based photoinitiators |
RU2013101781A (ru) | 2010-06-22 | 2014-07-27 | Колопласт А/С | Благоприятные для кожи адгезивы из фотоинициаторов на основе полиалкиловых эфиров |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3102839A (en) * | 1960-03-04 | 1963-09-03 | West Laboratories Inc | Germicidal compositions |
LU53667A1 (es) * | 1966-07-26 | 1968-11-29 | ||
GB1185044A (en) * | 1966-11-03 | 1970-03-18 | Ici Ltd | Alkanolamine Derivatives |
US3553332A (en) * | 1967-06-27 | 1971-01-05 | Hoffmann La Roche | Anti-tubercular benzophenone derivatives |
SE372762B (es) * | 1969-05-21 | 1975-01-13 | Haessle Ab | |
SE386892B (sv) * | 1972-07-06 | 1976-08-23 | Haessle Ab | Forfarande for framstellning av oxaminoforeningar |
US4201790A (en) * | 1975-06-20 | 1980-05-06 | May & Baker Limited | Benzophenone derivatives |
GB1495680A (en) * | 1975-06-20 | 1977-12-21 | May & Baker Ltd | 1-(2-benzoylphenoxy)-2-hydroxy-3-aminopropanes |
FR2330383A1 (fr) * | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
-
1980
- 1980-02-13 IT IT19887/80A patent/IT1147311B/it active
-
1981
- 1981-01-27 ES ES498846A patent/ES8201120A1/es not_active Expired
- 1981-02-10 JP JP56018891A patent/JPS6026381B2/ja not_active Expired
- 1981-02-11 DE DE19813104785 patent/DE3104785A1/de not_active Withdrawn
- 1981-02-11 FR FR8102669A patent/FR2475540A1/fr active Granted
- 1981-02-12 GB GB8104471A patent/GB2068963B/en not_active Expired
- 1981-02-12 ZA ZA00810946A patent/ZA81946B/xx unknown
- 1981-02-12 CA CA000370708A patent/CA1138897A/en not_active Expired
- 1981-02-12 US US06/233,948 patent/US4376788A/en not_active Expired - Fee Related
- 1981-02-13 AT AT0068781A patent/AT374450B/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATA68781A (de) | 1983-09-15 |
FR2475540A1 (fr) | 1981-08-14 |
ES498846A0 (es) | 1981-12-01 |
FR2475540B1 (es) | 1984-09-14 |
IT1147311B (it) | 1986-11-19 |
DE3104785A1 (de) | 1982-02-25 |
AT374450B (de) | 1984-04-25 |
JPS6026381B2 (ja) | 1985-06-24 |
IT8019887A0 (it) | 1980-02-13 |
GB2068963A (en) | 1981-08-19 |
US4376788A (en) | 1983-03-15 |
CA1138897A (en) | 1983-01-04 |
ZA81946B (en) | 1982-03-31 |
JPS56128742A (en) | 1981-10-08 |
GB2068963B (en) | 1983-06-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20010201 |