ES8201120A1 - Procedimiento de preparacion de eteres basicos de 4-hidro- xi-benzofenonas - Google Patents

Procedimiento de preparacion de eteres basicos de 4-hidro- xi-benzofenonas

Info

Publication number
ES8201120A1
ES8201120A1 ES498846A ES498846A ES8201120A1 ES 8201120 A1 ES8201120 A1 ES 8201120A1 ES 498846 A ES498846 A ES 498846A ES 498846 A ES498846 A ES 498846A ES 8201120 A1 ES8201120 A1 ES 8201120A1
Authority
ES
Spain
Prior art keywords
benzophenones
hydroxy
beta
acting
blocking agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES498846A
Other languages
English (en)
Other versions
ES498846A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STABIL BIOTERAPICO FARMACHIM
Original Assignee
STABIL BIOTERAPICO FARMACHIM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by STABIL BIOTERAPICO FARMACHIM filed Critical STABIL BIOTERAPICO FARMACHIM
Publication of ES498846A0 publication Critical patent/ES498846A0/es
Publication of ES8201120A1 publication Critical patent/ES8201120A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ETERES BASSICOS DE 4-HIDROXI-BENZOFENONAS, DE FORMULA (I), EN LA QUE R ES HIDROGENO O CLORO, Y R ES HIDROGENO O EL RADICAL COCH3. SE HACE REACCIONAR UNA 4-HIDROXI-BENZOFENONA DE FORMULA (II), EN LA QUE R Y R'' SON LOS MISMOS QUE EN LA FORMULA (I), CON EPICLORHIDRINA, EN ALCOHOL ANHIDRO Y EN PRESENCIA DE METOXIDO SODICO Y DEMETILFORMAMIDA, A UNOS 100 C, EL PRODUCTO RESULTANTE SE HACE REACCIONAR CON ISIPROPILAMINA EN ALCOHOL A UNA TEMPERATURA COMPRENDIDA ENTRE 35-40 C. EL COMPUESTO OBTENIDO SE SEPARA Y PURIFICA POR METODOS CONVENCIONALES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD BETABLOQUEADORA.
ES498846A 1980-02-13 1981-01-27 Procedimiento de preparacion de eteres basicos de 4-hidro- xi-benzofenonas Expired ES8201120A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19887/80A IT1147311B (it) 1980-02-13 1980-02-13 Eteri basici di 4-idrossi-benzofenoni con attivita' quali agenti betabloccanti e relativi procedimento di preparazione

Publications (2)

Publication Number Publication Date
ES498846A0 ES498846A0 (es) 1981-12-01
ES8201120A1 true ES8201120A1 (es) 1981-12-01

Family

ID=11162071

Family Applications (1)

Application Number Title Priority Date Filing Date
ES498846A Expired ES8201120A1 (es) 1980-02-13 1981-01-27 Procedimiento de preparacion de eteres basicos de 4-hidro- xi-benzofenonas

Country Status (10)

Country Link
US (1) US4376788A (es)
JP (1) JPS6026381B2 (es)
AT (1) AT374450B (es)
CA (1) CA1138897A (es)
DE (1) DE3104785A1 (es)
ES (1) ES8201120A1 (es)
FR (1) FR2475540A1 (es)
GB (1) GB2068963B (es)
IT (1) IT1147311B (es)
ZA (1) ZA81946B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63208911A (ja) * 1987-02-26 1988-08-30 Atsugi Motor Parts Co Ltd 圧力制御弁
WO2011012560A1 (en) 2009-07-30 2011-02-03 Basf Se Macrophotoinitiators
RU2572839C2 (ru) 2010-02-23 2016-01-20 Колопласт А/С Полимерные фотоинициаторы
SG186780A1 (en) 2010-06-22 2013-02-28 Coloplast As Hydrophilic gels from polyalkylether-based photoinitiators
RU2013101781A (ru) 2010-06-22 2014-07-27 Колопласт А/С Благоприятные для кожи адгезивы из фотоинициаторов на основе полиалкиловых эфиров

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3102839A (en) * 1960-03-04 1963-09-03 West Laboratories Inc Germicidal compositions
LU53667A1 (es) * 1966-07-26 1968-11-29
GB1185044A (en) * 1966-11-03 1970-03-18 Ici Ltd Alkanolamine Derivatives
US3553332A (en) * 1967-06-27 1971-01-05 Hoffmann La Roche Anti-tubercular benzophenone derivatives
SE372762B (es) * 1969-05-21 1975-01-13 Haessle Ab
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
US4201790A (en) * 1975-06-20 1980-05-06 May & Baker Limited Benzophenone derivatives
GB1495680A (en) * 1975-06-20 1977-12-21 May & Baker Ltd 1-(2-benzoylphenoxy)-2-hydroxy-3-aminopropanes
FR2330383A1 (fr) * 1975-11-06 1977-06-03 Synthelabo Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment

Also Published As

Publication number Publication date
ATA68781A (de) 1983-09-15
FR2475540A1 (fr) 1981-08-14
ES498846A0 (es) 1981-12-01
FR2475540B1 (es) 1984-09-14
IT1147311B (it) 1986-11-19
DE3104785A1 (de) 1982-02-25
AT374450B (de) 1984-04-25
JPS6026381B2 (ja) 1985-06-24
IT8019887A0 (it) 1980-02-13
GB2068963A (en) 1981-08-19
US4376788A (en) 1983-03-15
CA1138897A (en) 1983-01-04
ZA81946B (en) 1982-03-31
JPS56128742A (en) 1981-10-08
GB2068963B (en) 1983-06-02

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010201