ES8200886A1 - Procedimiento para la preparacion de derivados del amino-1 propanol-2 - Google Patents
Procedimiento para la preparacion de derivados del amino-1 propanol-2Info
- Publication number
- ES8200886A1 ES8200886A1 ES497563A ES497563A ES8200886A1 ES 8200886 A1 ES8200886 A1 ES 8200886A1 ES 497563 A ES497563 A ES 497563A ES 497563 A ES497563 A ES 497563A ES 8200886 A1 ES8200886 A1 ES 8200886A1
- Authority
- ES
- Spain
- Prior art keywords
- amino
- preparation
- therapeutic use
- propanol derivatives
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
- C07D333/80—Seven-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPERACION DE DERIVADOS DEL AMIMO-1 PROPANOL-2, DE FORMULA GENERAL (I), DONDE R1 Y R2 REPRESENTAN INDEPENDIENTEMENTE UN ATOMO / HIDROGENO, UN GRUPO ALQUILO LINEAL O RAMIFICADO CON UNO O DIEZ ATOMOS DE CARBONO, CICLOALQUILO MONO O POLICICLICO CON UNO A CATORCE ATOMOS DE CARBONO, ARILO O ARALCOILO CON UNO A CUATRO ATOMOS DE CARBONO EN LA FRACCION ALQUILO, ALCOXIALQUILO O ARILOXIALQUILO, Y N ES 1,2 O 3, Y SUS SALES DE ADICION, FARMACEUTICAMENTE ACEPTABLES. COMPRENDE LAS SIGUIENTES FASES OPERATIVAS: PRIMERA, CONDENSAR OXIMAS DE FORMULA (II) CON UNA EPIHALOHIDRINA, EN UN DISOLVENTE INERTE EN PRESENCIA DE UNA BASE Y A UNA TEMPERATURA COMPRENDIDAD ENTRE 10 GRDOS Y EL PUNTO DE EBULLICION DEL DISOLVENTE, PARA OBTENER COMPUESTOS DE FORMULA (III), DONDE N TIENE EL SIGNIFICDO YA INDICADO; SEGUNDA, CONDENSAR LOS COMPUESTOS DE FORMULA (III), CON UNA AMINA HNR1R2, DONDE R1 Y R2 TIENEN LOS SIGNIFICADOS YA INDICADOS, EN UN DISOLVENTE INERTE Y A UNA TEMPERATURA COMPRENDIDAD ENTRE 10 GRADOS Y LA TEMPERATURA DE EBULLICION DEL DISOLVENTE,
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7931402A FR2471980A1 (fr) | 1979-12-21 | 1979-12-21 | Nouveaux derives de l'amino-1 propanol-2, leur procede de preparation et leur application therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8200886A1 true ES8200886A1 (es) | 1981-11-16 |
| ES497563A0 ES497563A0 (es) | 1981-11-16 |
Family
ID=9233060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES497563A Granted ES497563A0 (es) | 1979-12-21 | 1980-12-10 | Procedimiento para la preparacion de derivados del amino-1 propanol-2 |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4339450A (es) |
| EP (1) | EP0031266B1 (es) |
| JP (1) | JPS5699472A (es) |
| AR (1) | AR225937A1 (es) |
| AU (1) | AU541684B2 (es) |
| BE (1) | BE886471A (es) |
| BG (1) | BG35047A3 (es) |
| CA (1) | CA1158643A (es) |
| CH (1) | CH646165A5 (es) |
| CS (1) | CS228143B2 (es) |
| DE (1) | DE3061928D1 (es) |
| DK (1) | DK536180A (es) |
| ES (1) | ES497563A0 (es) |
| FR (1) | FR2471980A1 (es) |
| GB (1) | GB2066808B (es) |
| GR (1) | GR72831B (es) |
| HU (1) | HU181774B (es) |
| IE (1) | IE50546B1 (es) |
| IL (1) | IL61602A (es) |
| IN (1) | IN150867B (es) |
| IT (1) | IT1141642B (es) |
| LU (1) | LU83021A1 (es) |
| NZ (1) | NZ195786A (es) |
| PL (1) | PL127009B1 (es) |
| PT (1) | PT72247B (es) |
| RO (1) | RO80266B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3704604A1 (de) * | 1987-02-13 | 1988-08-25 | Mack Chem Pharm | Oximether von 2,6-dioxabicyclo(3.3.0)octanonen, herstellungsverfahren und anwendung als arzneimittel |
| US4803286A (en) * | 1987-08-19 | 1989-02-07 | Merck & Co., Inc. | Amino-2-hydroxypropyloximinoheterocycle α-blockers |
| EP0347378A1 (de) * | 1988-06-13 | 1989-12-20 | Ciba-Geigy Ag | Imidazol-Derivate |
| IL103106A (en) | 1991-09-25 | 1998-06-15 | Sanofi Elf | Sites of tynocyclopentanone oximes, their preparation and pharmaceutical preparations containing them |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3398161A (en) * | 1965-06-30 | 1968-08-20 | Ici Ltd | Benzo (b) thiophen derivatives which have beta-adrenergic blocking activity |
| NL6810133A (es) * | 1968-07-18 | 1970-01-20 |
-
1979
- 1979-12-21 FR FR7931402A patent/FR2471980A1/fr active Granted
-
1980
- 1980-11-15 GR GR63372A patent/GR72831B/el unknown
- 1980-11-18 GB GB8036920A patent/GB2066808B/en not_active Expired
- 1980-12-01 EP EP80401713A patent/EP0031266B1/fr not_active Expired
- 1980-12-01 IL IL8061602A patent/IL61602A/xx unknown
- 1980-12-01 DE DE8080401713T patent/DE3061928D1/de not_active Expired
- 1980-12-02 CH CH893680A patent/CH646165A5/fr not_active IP Right Cessation
- 1980-12-03 BE BE0/203024A patent/BE886471A/fr not_active IP Right Cessation
- 1980-12-04 IE IE2535/80A patent/IE50546B1/en unknown
- 1980-12-09 NZ NZ195786A patent/NZ195786A/xx unknown
- 1980-12-10 ES ES497563A patent/ES497563A0/es active Granted
- 1980-12-12 BG BG8049969A patent/BG35047A3/xx unknown
- 1980-12-16 RO RO102863A patent/RO80266B/ro unknown
- 1980-12-17 DK DK536180A patent/DK536180A/da not_active Application Discontinuation
- 1980-12-17 AR AR283678A patent/AR225937A1/es active
- 1980-12-18 IT IT68942/80A patent/IT1141642B/it active
- 1980-12-18 CA CA000367082A patent/CA1158643A/en not_active Expired
- 1980-12-19 AU AU65587/80A patent/AU541684B2/en not_active Ceased
- 1980-12-19 HU HU803060A patent/HU181774B/hu unknown
- 1980-12-19 PL PL1980228606A patent/PL127009B1/pl unknown
- 1980-12-19 LU LU83021A patent/LU83021A1/fr unknown
- 1980-12-19 CS CS809065A patent/CS228143B2/cs unknown
- 1980-12-19 PT PT72247A patent/PT72247B/pt unknown
- 1980-12-22 US US06/219,213 patent/US4339450A/en not_active Expired - Fee Related
- 1980-12-22 JP JP18180280A patent/JPS5699472A/ja active Pending
-
1981
- 1981-01-17 IN IN54/CAL/81A patent/IN150867B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL127009B1 (en) | 1983-09-30 |
| GB2066808B (en) | 1983-07-06 |
| BE886471A (fr) | 1981-04-01 |
| BG35047A3 (en) | 1984-01-16 |
| FR2471980B1 (es) | 1982-07-30 |
| DE3061928D1 (en) | 1983-03-17 |
| NZ195786A (en) | 1982-09-14 |
| IT1141642B (it) | 1986-10-01 |
| GR72831B (es) | 1983-12-06 |
| IE50546B1 (en) | 1986-05-14 |
| AU541684B2 (en) | 1985-01-17 |
| PT72247A (fr) | 1981-01-01 |
| IT8068942A0 (it) | 1980-12-18 |
| IL61602A0 (en) | 1981-09-13 |
| GB2066808A (en) | 1981-07-15 |
| EP0031266B1 (fr) | 1983-02-09 |
| IL61602A (en) | 1984-05-31 |
| AU6558780A (en) | 1981-06-25 |
| HU181774B (en) | 1983-11-28 |
| CA1158643A (en) | 1983-12-13 |
| IE802535L (en) | 1981-06-21 |
| EP0031266A1 (fr) | 1981-07-01 |
| IN150867B (es) | 1983-01-01 |
| JPS5699472A (en) | 1981-08-10 |
| RO80266B (ro) | 1983-04-30 |
| US4339450A (en) | 1982-07-13 |
| PL228606A1 (es) | 1981-08-21 |
| LU83021A1 (fr) | 1981-03-27 |
| RO80266A (ro) | 1983-04-29 |
| AR225937A1 (es) | 1982-05-14 |
| FR2471980A1 (fr) | 1981-06-26 |
| CS228143B2 (en) | 1984-05-14 |
| PT72247B (fr) | 1981-11-05 |
| CH646165A5 (fr) | 1984-11-15 |
| DK536180A (da) | 1981-06-22 |
| ES497563A0 (es) | 1981-11-16 |
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