ES8200110A1 - Un procedimiento para preparar la sal de d-sesquisodio del compuesto diacido de oxa-beta-lactama - Google Patents
Un procedimiento para preparar la sal de d-sesquisodio del compuesto diacido de oxa-beta-lactamaInfo
- Publication number
- ES8200110A1 ES8200110A1 ES490828A ES490828A ES8200110A1 ES 8200110 A1 ES8200110 A1 ES 8200110A1 ES 490828 A ES490828 A ES 490828A ES 490828 A ES490828 A ES 490828A ES 8200110 A1 ES8200110 A1 ES 8200110A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- oxa
- beta
- diacid compound
- sesquisodium salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DEL ISOMERO D DE LA SAL DE SESQUISODIO DEL COMPUESTO DIACIDO DE OXA-B-LACTAMA DE FORMULA (I). SE HACE REACCIONAR LA SAL DISODICA D,L DE FORMULA (II) CON EL DIACIDO D,L DE FORMULA (III), MEDIANTE LA ADICION DE ACETONA A UNA SOLUCION ACUOSA EN LA QUE LA RELACION MOLAR DE LA DISAL AL DIACIDO ESTA COMPRENDIDA ENTRE 1 A 1 Y 6 A 1. POSTERIORMENTE SE ENFRIA LA SOLUCION A UNA TEMPERATURA COMPRENDIDA ENTRE -35 Y -10 C. DE APLICACION EN EL TRATAMIENTO DE INFECCIONES PROVOCADAS POR BACTERIAS TANTO GRAM-POSITIVAS COMO GRAM-NEGATIVAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/032,840 US4259485A (en) | 1979-04-24 | 1979-04-24 | Crystallization process |
Publications (2)
Publication Number | Publication Date |
---|---|
ES490828A0 ES490828A0 (es) | 1981-10-16 |
ES8200110A1 true ES8200110A1 (es) | 1981-10-16 |
Family
ID=21867102
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES490828A Expired ES8200110A1 (es) | 1979-04-24 | 1980-04-23 | Un procedimiento para preparar la sal de d-sesquisodio del compuesto diacido de oxa-beta-lactama |
Country Status (34)
Country | Link |
---|---|
US (1) | US4259485A (es) |
EP (1) | EP0018760B1 (es) |
JP (1) | JPS55143992A (es) |
KR (1) | KR840000036B1 (es) |
AR (1) | AR225174A1 (es) |
AT (1) | AT368158B (es) |
AU (1) | AU531272B2 (es) |
BE (1) | BE882849A (es) |
BG (1) | BG34904A3 (es) |
CA (1) | CA1124236A (es) |
CH (1) | CH645901A5 (es) |
CS (1) | CS212347B2 (es) |
DD (1) | DD150205A5 (es) |
DE (1) | DE3067412D1 (es) |
DK (1) | DK172880A (es) |
EG (1) | EG14334A (es) |
ES (1) | ES8200110A1 (es) |
FI (1) | FI801252A (es) |
FR (1) | FR2455043A1 (es) |
GB (1) | GB2047703B (es) |
GR (1) | GR68048B (es) |
HU (1) | HU182127B (es) |
IE (1) | IE49703B1 (es) |
IL (1) | IL59895A (es) |
IT (1) | IT1141294B (es) |
LU (1) | LU82384A1 (es) |
NZ (1) | NZ193482A (es) |
PH (1) | PH15146A (es) |
PL (1) | PL124423B1 (es) |
PT (1) | PT71115A (es) |
RO (1) | RO79315A (es) |
SU (1) | SU925251A3 (es) |
YU (1) | YU108180A (es) |
ZA (1) | ZA802329B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56103185A (en) * | 1980-01-22 | 1981-08-18 | Shionogi & Co Ltd | Malonamidoxa-dethia-cephem compound |
JPS5711909A (en) * | 1980-06-23 | 1982-01-21 | Shionogi & Co Ltd | Stable freeze-dried preparation of beta-lactam |
JPS597193A (ja) * | 1982-07-02 | 1984-01-14 | Shionogi & Co Ltd | マロニルメチル基の異性化方法 |
RU2555360C2 (ru) * | 2012-11-06 | 2015-07-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Способ определения воды в координационных соединениях |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1085392A (en) * | 1976-03-25 | 1980-09-09 | Masayuki Narisada | Arylmalonamido-1-oxadethiacephalosporins |
AU514377B2 (en) * | 1977-02-15 | 1981-02-05 | Shionogi & Co., Ltd. | l-OXADETHIACEPHAM COMPOUNDS |
CA1100962A (en) * | 1977-04-28 | 1981-05-12 | Yoshio Hamashima | Haloarylmalonamidooxacephalosporins |
JPS609718B2 (ja) * | 1977-08-25 | 1985-03-12 | 塩野義製薬株式会社 | チアジアゾリルチオセフアロスポリン類縁抗生物質 |
BE871213R (fr) * | 1978-10-12 | 1979-02-01 | Shionogi & Co | Arylmalonamido-1-oxadethiacephalosporines |
-
1979
- 1979-04-24 US US06/032,840 patent/US4259485A/en not_active Expired - Lifetime
-
1980
- 1980-04-17 AT AT0207380A patent/AT368158B/de not_active IP Right Cessation
- 1980-04-18 FR FR8008779A patent/FR2455043A1/fr active Granted
- 1980-04-18 BE BE1/9791A patent/BE882849A/fr not_active IP Right Cessation
- 1980-04-18 NZ NZ193482A patent/NZ193482A/xx unknown
- 1980-04-18 CS CS802746A patent/CS212347B2/cs unknown
- 1980-04-18 GB GB8012882A patent/GB2047703B/en not_active Expired
- 1980-04-18 DE DE8080301269T patent/DE3067412D1/de not_active Expired
- 1980-04-18 CA CA350,223A patent/CA1124236A/en not_active Expired
- 1980-04-18 FI FI801252A patent/FI801252A/fi not_active Application Discontinuation
- 1980-04-18 EP EP80301269A patent/EP0018760B1/en not_active Expired
- 1980-04-18 PT PT71115A patent/PT71115A/pt unknown
- 1980-04-18 ZA ZA00802329A patent/ZA802329B/xx unknown
- 1980-04-19 GR GR61721A patent/GR68048B/el unknown
- 1980-04-21 RO RO80100909A patent/RO79315A/ro unknown
- 1980-04-21 PH PH23926A patent/PH15146A/en unknown
- 1980-04-21 PL PL1980223649A patent/PL124423B1/pl unknown
- 1980-04-21 YU YU01081/80A patent/YU108180A/xx unknown
- 1980-04-21 IT IT21527/80A patent/IT1141294B/it active
- 1980-04-21 AU AU57633/80A patent/AU531272B2/en not_active Expired - Fee Related
- 1980-04-22 BG BG8047486A patent/BG34904A3/xx unknown
- 1980-04-22 EG EG246/80A patent/EG14334A/xx active
- 1980-04-22 AR AR280762A patent/AR225174A1/es active
- 1980-04-22 IL IL59895A patent/IL59895A/xx not_active IP Right Cessation
- 1980-04-22 CH CH309480A patent/CH645901A5/fr not_active IP Right Cessation
- 1980-04-22 HU HU80987A patent/HU182127B/hu not_active IP Right Cessation
- 1980-04-22 LU LU82384A patent/LU82384A1/fr unknown
- 1980-04-22 IE IE804/80A patent/IE49703B1/en not_active IP Right Cessation
- 1980-04-23 ES ES490828A patent/ES8200110A1/es not_active Expired
- 1980-04-23 SU SU802912148A patent/SU925251A3/ru active
- 1980-04-23 JP JP5485180A patent/JPS55143992A/ja active Granted
- 1980-04-23 DK DK172880A patent/DK172880A/da not_active IP Right Cessation
- 1980-04-24 KR KR1019800001690A patent/KR840000036B1/ko active
- 1980-04-24 DD DD80220683A patent/DD150205A5/de unknown
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