ES8105254A1 - Un procedimiento para la preparacion de acido 2-(4-dimetil- vinilfenil) propionico - Google Patents
Un procedimiento para la preparacion de acido 2-(4-dimetil- vinilfenil) propionicoInfo
- Publication number
- ES8105254A1 ES8105254A1 ES492556A ES492556A ES8105254A1 ES 8105254 A1 ES8105254 A1 ES 8105254A1 ES 492556 A ES492556 A ES 492556A ES 492556 A ES492556 A ES 492556A ES 8105254 A1 ES8105254 A1 ES 8105254A1
- Authority
- ES
- Spain
- Prior art keywords
- alkanoic acid
- acid compound
- dehydration
- esters
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/807—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen all halogen atoms bound to the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE ACIDO 2-(4-DIMETILVINILFENIL)PROPIONICO. CONSISTE EN DESHIDRATAR UN COMPUESTO DE FORMULA GENERAL (I), DONDE R REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO C1-4 ALCOHOIL (C2-5) OXIMETILO. CUANDO R ES UN ATOMO DE HIDROGENO, OPCIONALMENTE, LA DESHIDRATACION SE EFECTUA EN PRESENCIA DE UN ALCANOL C1-4, Y SI SE DESEA SE CONVIERTE EL ACIDO OBTENIDO EN LA SAL FISIOLOGICAMENTE ACEPTABLE, TAL COMO LA SAL DE CALCIO O DE D1-LISINA DEL ACIDO 2-(4-DIMETILVINILFENIL)PROPIONICO. *FORMULA* ACTIVIDAD ANTI-INFLAMATORIA. I
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7921083 | 1979-06-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8105254A1 true ES8105254A1 (es) | 1981-06-01 |
ES492556A0 ES492556A0 (es) | 1981-06-01 |
Family
ID=10505908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES492556A Granted ES492556A0 (es) | 1979-06-18 | 1980-06-18 | Un procedimiento para la preparacion de acido 2-(4-dimetil- vinilfenil) propionico |
Country Status (10)
Country | Link |
---|---|
US (1) | US4362891A (es) |
JP (1) | JPS5639039A (es) |
CH (1) | CH646935A5 (es) |
DE (1) | DE3022599A1 (es) |
ES (1) | ES492556A0 (es) |
FR (1) | FR2459219A1 (es) |
GB (1) | GB2055363B (es) |
GR (1) | GR68764B (es) |
IT (2) | IT1143921B (es) |
PT (1) | PT71405B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57203035A (en) * | 1981-06-05 | 1982-12-13 | Taisho Pharmaceut Co Ltd | Carboxylic acid ester |
JPS58225039A (ja) * | 1982-06-22 | 1983-12-27 | Eisai Co Ltd | ポリプレニル系化合物 |
DE3360677D1 (en) * | 1982-11-11 | 1985-10-03 | Beecham Group Plc | Arachidonic acid analogues, processes for their preparation and their use in medicine |
JPS59212439A (ja) * | 1983-05-19 | 1984-12-01 | Taisho Pharmaceut Co Ltd | スチレン誘導体 |
US4499300A (en) * | 1983-12-27 | 1985-02-12 | Uop Inc. | 4-Vinylbenzeneacetic acid |
US5244920A (en) * | 1985-04-15 | 1993-09-14 | Schering Spa | Pharmaceutical compositions having therapeutical activity based on mercaptoethansulphonic arginine salt |
IT1185551B (it) * | 1985-04-15 | 1987-11-12 | Schering Spa | Composizioni farmaceutiche a base di acido mercaptoetansolfonico ad attivita' terapeutica,derivati salini organici dell'acido mercaptoetansolfonico utili per tali composizioni e relativo procedimento di preparazione |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3385887A (en) * | 1961-02-02 | 1968-05-28 | Boots Pure Drug Co Ltd | 4-isobutylphenylacetic acid |
GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
GB1012480A (en) | 1962-07-26 | 1965-12-08 | Boots Pure Drug Co Ltd | Anti-inflammatory agents |
US3397225A (en) * | 1964-06-15 | 1968-08-13 | Union Oil Co | Preparation of esters of unsaturated acids |
CH474469A (fr) * | 1966-09-08 | 1969-06-30 | Boots Pure Drug Co Ltd | Procédé de préparation d'acides a-phénylpropioniques |
US3652608A (en) * | 1968-09-20 | 1972-03-28 | Union Oil Co | Preparation of unsaturated esters |
US3729509A (en) * | 1970-04-20 | 1973-04-24 | Merck & Co Inc | (mono-and diacylvinyl)aryl alkanoic(and alkenoic)acids |
US3649668A (en) * | 1970-06-15 | 1972-03-14 | Dow Chemical Co | Halogen containing esters of vinyl arylene acetic acid |
GB1459084A (en) * | 1973-05-24 | 1976-12-22 | Boots Co Ltd | Preparation of arylalkanoic acid |
IT1059677B (it) * | 1974-03-22 | 1982-06-21 | Neopharmed Spa | Sale di lisina ad azione terapeutica |
JPS54163545A (en) * | 1978-06-10 | 1979-12-26 | Taisho Pharmaceutical Co Ltd | Organic carboxylic acid derivative |
-
1980
- 1980-06-16 DE DE19803022599 patent/DE3022599A1/de not_active Withdrawn
- 1980-06-17 JP JP8206180A patent/JPS5639039A/ja active Pending
- 1980-06-17 CH CH464580A patent/CH646935A5/de not_active IP Right Cessation
- 1980-06-17 PT PT71405A patent/PT71405B/pt unknown
- 1980-06-17 FR FR8013439A patent/FR2459219A1/fr active Granted
- 1980-06-17 IT IT48996/80A patent/IT1143921B/it active
- 1980-06-17 US US06/160,426 patent/US4362891A/en not_active Expired - Lifetime
- 1980-06-17 IT IT48995/80A patent/IT1128163B/it active
- 1980-06-17 GR GR62217A patent/GR68764B/el unknown
- 1980-06-17 GB GB8019834A patent/GB2055363B/en not_active Expired
- 1980-06-18 ES ES492556A patent/ES492556A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
PT71405B (en) | 1981-10-22 |
GR68764B (es) | 1982-02-17 |
IT1143921B (it) | 1986-10-29 |
IT8048996A0 (it) | 1980-06-17 |
IT1128163B (it) | 1986-05-28 |
GB2055363B (en) | 1983-04-13 |
CH646935A5 (de) | 1984-12-28 |
IT8048995A0 (it) | 1980-06-17 |
DE3022599A1 (de) | 1981-01-08 |
FR2459219B1 (es) | 1983-11-25 |
FR2459219A1 (fr) | 1981-01-09 |
PT71405A (en) | 1980-07-01 |
JPS5639039A (en) | 1981-04-14 |
US4362891A (en) | 1982-12-07 |
GB2055363A (en) | 1981-03-04 |
ES492556A0 (es) | 1981-06-01 |
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