ES8103109A1 - Procedimiento para la obtencion de hidrazidas de acido fos- fonoformico - Google Patents

Procedimiento para la obtencion de hidrazidas de acido fos- fonoformico

Info

Publication number
ES8103109A1
ES8103109A1 ES493027A ES493027A ES8103109A1 ES 8103109 A1 ES8103109 A1 ES 8103109A1 ES 493027 A ES493027 A ES 493027A ES 493027 A ES493027 A ES 493027A ES 8103109 A1 ES8103109 A1 ES 8103109A1
Authority
ES
Spain
Prior art keywords
phosphonoformic acid
compounds
medicines
preparation
acid hydrazides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493027A
Other languages
English (en)
Other versions
ES493027A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES493027A0 publication Critical patent/ES493027A0/es
Publication of ES8103109A1 publication Critical patent/ES8103109A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4062—Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
    • C07F9/4065—Esters of acids containing the structure -C(=X)-P(=X)(XR)2, (X = O, S, Se)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3886—Acids containing the structure -C(=X)-P(=X)(XH)2 or NC-P(=X)(XH)2, (X = O, S, Se)
    • C07F9/3891—Acids containing the structure -C(=X)-P(=X)(XH)2, (X = O, S, Se)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE HIDRAZIDAS DE ACIDO FOSFONOFORMICO DE FORMULA (I), DONDE R SIGNIFICA HIDROGENO O AQLUILO DE HASTA 6 ATOMOS DE CARBONO, Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES. SE HACE REACIONAR UN ESTER DE ACIDO FOSFONOFORMICO DE FORMULA (II), DONDE R1 ES UN ALQUILO Y R2 PUEDE SER ALQUILO O ARILO, CON UN HALURO DE TRIALQUIL-SILILO DE FORMULA (III), DONDE R3 ES UN RESTO ALQUILICO Y HAL PUEDE SER BROMO O YODO, EN FORMA DE SUS SALES, CON UNA HIDRAZINA MONOSUSTITUIDA CON R. TAMBIEN SE TIENE OTROS METODOS ALTERNATIVOS DE OBTENCION. POSEEN ACTIVIDAD ANTIVIRAL Y SON UTILIZABLES EN MEDICINA HUMANA Y VETERINARIA. *FORMULA*.
ES493027A 1979-07-03 1980-07-02 Procedimiento para la obtencion de hidrazidas de acido fos- fonoformico Expired ES8103109A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792926799 DE2926799A1 (de) 1979-07-03 1979-07-03 Phosphonoameisensaeurehydrazide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
ES493027A0 ES493027A0 (es) 1981-02-16
ES8103109A1 true ES8103109A1 (es) 1981-02-16

Family

ID=6074790

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493027A Expired ES8103109A1 (es) 1979-07-03 1980-07-02 Procedimiento para la obtencion de hidrazidas de acido fos- fonoformico

Country Status (10)

Country Link
US (1) US4308263A (es)
EP (1) EP0021391B1 (es)
JP (1) JPS5610199A (es)
AT (1) ATE1507T1 (es)
AU (1) AU6005880A (es)
DE (2) DE2926799A1 (es)
DK (1) DK286880A (es)
ES (1) ES8103109A1 (es)
FI (1) FI802089A (es)
NO (1) NO801880L (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2520364A1 (fr) * 1982-01-28 1983-07-29 Richard Marcel Medicament utilisable notamment en psychiatrie, utilisant comme principe actif un n-alkylcarbamoylphosphate de lithium
US4438013A (en) 1983-05-27 1984-03-20 Olin Corporation Phosphorylated and thiophosphorylated poly(oxyalkylated) hydrazines and selected adducts and their use as corrosion inhibitors
EP0129628A1 (fr) * 1983-06-23 1985-01-02 Marcel Richard Médicament, utilisable notamment en psychiatrie, utilisant comme principe actif un N- alkylcarbamoylphosphate de lithium
US20080103046A1 (en) * 2006-08-24 2008-05-01 Francine Palmer Process for making a plant growth regulator
RU2754979C9 (ru) * 2021-01-11 2021-10-22 федеральное государственное бюджетное образовательное учреждение высшего образования "Казанский национальный исследовательский технологический университет" (ФГБОУ ВО "КНИТУ") Антимикотическое и бактерицидное средство

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4092412A (en) * 1976-04-30 1978-05-30 Abbott Laboratories Treatment of herpes simplex infections
SE7607496L (sv) * 1976-07-01 1978-01-02 Astra Laekemedel Ab Sett for bekempning av virusinfektioner
US4087522A (en) * 1976-09-08 1978-05-02 Abbott Laboratories Amides of phosphonoacetic acid for treating herpes simplex virus type 1 and 2 infections
US4150125A (en) * 1977-09-30 1979-04-17 Abbott Laboratories Triglyceride ester of phosphonoacetic acid having antiviral activity
US4162311A (en) * 1977-11-04 1979-07-24 Avrutsky Grigory Y Medicinal preparation with pronounced vegetotropic and antiepileptic effect for treating psychoneurotic disorders
DK564378A (da) * 1977-12-22 1979-06-23 Astra Laekemedel Ab Fremgangsmaade til fremstilling af amidderivater til bekaempelse af virusinfektioner

Also Published As

Publication number Publication date
DE2926799A1 (de) 1981-01-15
ATE1507T1 (de) 1982-09-15
EP0021391B1 (de) 1982-09-01
DK286880A (da) 1981-01-04
DE3060804D1 (en) 1982-10-28
FI802089A (fi) 1981-01-04
AU6005880A (en) 1981-01-15
ES493027A0 (es) 1981-02-16
JPS5610199A (en) 1981-02-02
NO801880L (no) 1981-01-05
EP0021391A1 (de) 1981-01-07
US4308263A (en) 1981-12-29

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