ES8101560A1 - Benzimidazole-carbamates - Google Patents

Benzimidazole-carbamates

Info

Publication number
ES8101560A1
ES8101560A1 ES486612A ES486612A ES8101560A1 ES 8101560 A1 ES8101560 A1 ES 8101560A1 ES 486612 A ES486612 A ES 486612A ES 486612 A ES486612 A ES 486612A ES 8101560 A1 ES8101560 A1 ES 8101560A1
Authority
ES
Spain
Prior art keywords
carbamates
benzimidazole
hydrogen
independently represent
methyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486612A
Other languages
Spanish (es)
Other versions
ES486612A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Montedison SpA
Original Assignee
Montedison SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT30618/78A external-priority patent/IT1100788B/en
Priority claimed from IT26734/79A external-priority patent/IT1125577B/en
Application filed by Montedison SpA filed Critical Montedison SpA
Publication of ES486612A0 publication Critical patent/ES486612A0/en
Publication of ES8101560A1 publication Critical patent/ES8101560A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C21/00Acyclic unsaturated compounds containing halogen atoms
    • C07C21/02Acyclic unsaturated compounds containing halogen atoms containing carbon-to-carbon double bonds
    • C07C21/04Chloro-alkenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/26Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/272Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by addition reactions
    • C07C17/275Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by addition reactions of hydrocarbons and halogenated hydrocarbons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C21/00Acyclic unsaturated compounds containing halogen atoms
    • C07C21/02Acyclic unsaturated compounds containing halogen atoms containing carbon-to-carbon double bonds
    • C07C21/14Acyclic unsaturated compounds containing halogen atoms containing carbon-to-carbon double bonds containing bromine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C21/00Acyclic unsaturated compounds containing halogen atoms
    • C07C21/02Acyclic unsaturated compounds containing halogen atoms containing carbon-to-carbon double bonds
    • C07C21/18Acyclic unsaturated compounds containing halogen atoms containing carbon-to-carbon double bonds containing fluorine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30Nitrogen atoms not forming part of a nitro radical
    • C07D235/32Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Benzimidazole-carbamates endowed with anthelmintic activity have the general formula: < IMAGE > in which: R represents an alkyl group having 1 to 4 carbon atoms, R<1> and R<2> independently represent a hydrogen or halogen atom or a methyl group optionally substituted with one or more halogen atoms, R<3> and R<4> independently represent a hydrogen or chlorine atom or a methyl group, and X represents O, S, SO or SO2.
ES486612A 1978-12-06 1979-12-05 Benzimidazole-carbamates Expired ES8101560A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT30618/78A IT1100788B (en) 1978-12-06 1978-12-06 Benzimidazole-carbamates
IT26734/79A IT1125577B (en) 1979-10-24 1979-10-24 5(6)-Substd. benzimidazole-2-carbamate ester(s)

Publications (2)

Publication Number Publication Date
ES486612A0 ES486612A0 (en) 1980-12-16
ES8101560A1 true ES8101560A1 (en) 1980-12-16

Family

ID=26328693

Family Applications (1)

Application Number Title Priority Date Filing Date
ES486612A Expired ES8101560A1 (en) 1978-12-06 1979-12-05 Benzimidazole-carbamates

Country Status (22)

Country Link
AR (1) AR222847A1 (en)
AT (1) AT364832B (en)
AU (1) AU536133B2 (en)
BR (1) BR7907892A (en)
CA (1) CA1150280A (en)
CS (1) CS242859B2 (en)
DD (1) DD147539A5 (en)
DE (1) DE2948885A1 (en)
DK (1) DK157547C (en)
ES (1) ES8101560A1 (en)
FR (2) FR2443461A1 (en)
GB (1) GB2037758B (en)
HU (1) HU183093B (en)
IE (1) IE49976B1 (en)
IL (1) IL58885A (en)
KE (1) KE3326A (en)
MX (1) MX6197E (en)
NL (1) NL7908719A (en)
NZ (1) NZ192311A (en)
PL (1) PL126932B1 (en)
SE (1) SE445641B (en)
SU (1) SU1169532A3 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU628671B2 (en) * 1989-10-12 1992-09-17 Michael John Crooks Non-aqueous micellar solutions of various drugs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929821A (en) * 1972-12-29 1975-12-30 Syntex Inc 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives
DE2334631A1 (en) * 1973-07-07 1975-03-27 Hoechst Ag 5-PHENYLSULFINYL-2-BENZIMIDAZOLE CARBAMIC ACID ESTERS AND THE METHOD FOR THEIR MANUFACTURE
US3915986A (en) * 1974-06-19 1975-10-28 Smithkline Corp Methyl 5-propylthio-2-benzimidazolecarbamate
IT1076022B (en) * 1977-04-20 1985-04-22 Montedison Spa ANTIELMINTIC BENZIMIDAZOLCARBAMMATES
HU177182B (en) * 1977-05-10 1981-08-28 Chinoin Gyogyszer Es Vegyeszet Process for producing tetraamino-diphenyl-disulfide derivatives
AU4185678A (en) * 1978-01-09 1979-07-19 Squibb & Sons Inc Derivatives of benzimidazoles

Also Published As

Publication number Publication date
GB2037758A (en) 1980-07-16
PL220185A1 (en) 1980-12-01
HU183093B (en) 1984-04-28
ES486612A0 (en) 1980-12-16
FR2445306B1 (en) 1982-12-10
GB2037758B (en) 1983-05-05
AU536133B2 (en) 1984-04-19
FR2445306A1 (en) 1980-07-25
AU5341779A (en) 1980-06-12
AR222847A1 (en) 1981-06-30
IL58885A0 (en) 1980-03-31
FR2443461A1 (en) 1980-07-04
BR7907892A (en) 1980-07-22
SU1169532A3 (en) 1985-07-23
ATA770279A (en) 1981-04-15
SE445641B (en) 1986-07-07
FR2443461B1 (en) 1983-05-13
DE2948885A1 (en) 1980-06-19
NZ192311A (en) 1982-12-21
CS242859B2 (en) 1986-05-15
DK157547B (en) 1990-01-22
SE7909932L (en) 1980-06-07
DK512179A (en) 1980-06-07
IL58885A (en) 1985-01-31
DE2948885C2 (en) 1990-05-23
IE49976B1 (en) 1986-01-22
CS839779A2 (en) 1985-08-15
CA1150280A (en) 1983-07-19
DK157547C (en) 1990-06-25
NL7908719A (en) 1980-06-10
IE792347L (en) 1980-06-06
AT364832B (en) 1981-11-25
KE3326A (en) 1983-09-16
MX6197E (en) 1984-12-13
DD147539A5 (en) 1981-04-08
PL126932B1 (en) 1983-09-30

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506