ES8101539A1 - Un procedimiento para la preparacion de derivados de la in- danona. - Google Patents

Un procedimiento para la preparacion de derivados de la in- danona.

Info

Publication number
ES8101539A1
ES8101539A1 ES481102A ES481102A ES8101539A1 ES 8101539 A1 ES8101539 A1 ES 8101539A1 ES 481102 A ES481102 A ES 481102A ES 481102 A ES481102 A ES 481102A ES 8101539 A1 ES8101539 A1 ES 8101539A1
Authority
ES
Spain
Prior art keywords
preparation
lower alkyl
medicaments containing
indanamine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES481102A
Other languages
English (en)
Other versions
ES481102A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Japan Co Ltd
Original Assignee
Hokuriku Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP6382178A external-priority patent/JPS54157551A/ja
Priority claimed from JP6382278A external-priority patent/JPS54157552A/ja
Priority claimed from JP54034349A external-priority patent/JPS581102B2/ja
Application filed by Hokuriku Pharmaceutical Co Ltd filed Critical Hokuriku Pharmaceutical Co Ltd
Publication of ES8101539A1 publication Critical patent/ES8101539A1/es
Publication of ES481102A0 publication Critical patent/ES481102A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE LA INDANONA. CONSISTE EN SOMETER UN COMPUESTO HIDROXILIMINO DE FORMULA GENERAL (I) A UNA HIDROGENACION CATOLITICA EN PRESENCIA DE NIQUEL RAMY, OXIDO DE PT, CARBON PALADICO, EN UN DISOLVENTE ORGANICO, TAL COMO ACIDO ACETICO, ETANOL, METANOL. LA HIDROGENACION SE LLEVA A CABO BAJO PRESION DE 20 A 50 ATMOSFERAS Y A UNA TEMPERATURA DE 50 A 100GC, DURANTE UN TEMPO DE 2 A 10 HORAS. SE OBTIENE UN COMPUESTO (II), QUE PUEDE SER TRANSFORMADOR POR HIDROLISIS EN PRESENCIA DE NACH O KOH EN UN DISOLVENTE ORGANICO, TAL COMO ETILENGLICOL A REFLUJO MEDIANTE CALENTAMEITNO; LA REACCION DURA DE 5 A 48 HORAS. *FORMULA* ACTIVIDAD ANALGESICA.
ES481102A 1978-05-30 1979-05-30 Un procedimiento para la preparacion de derivados de la in- danona. Granted ES481102A0 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP6382178A JPS54157551A (en) 1978-05-30 1978-05-30 Indanamine derivative
JP6382278A JPS54157552A (en) 1978-05-30 1978-05-30 Indanamine derivative
JP54034349A JPS581102B2 (ja) 1979-03-26 1979-03-26 インダナミン誘導体

Publications (2)

Publication Number Publication Date
ES8101539A1 true ES8101539A1 (es) 1980-12-16
ES481102A0 ES481102A0 (es) 1980-12-16

Family

ID=27288395

Family Applications (1)

Application Number Title Priority Date Filing Date
ES481102A Granted ES481102A0 (es) 1978-05-30 1979-05-30 Un procedimiento para la preparacion de derivados de la in- danona.

Country Status (5)

Country Link
EP (1) EP0005821B1 (es)
CA (1) CA1109080A (es)
DE (1) DE2964198D1 (es)
DK (1) DK225279A (es)
ES (1) ES481102A0 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2603035B1 (fr) * 1986-08-21 1988-12-09 Roussel Uclaf Nouveaux derives de l'indane, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
FR2617480B1 (fr) * 1987-07-03 1990-12-07 Roussel Uclaf Nouveaux derives de l'indane, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
CA1245663A (en) * 1983-03-04 1988-11-29 Yasuo Oshiro 1-nitrogen containing-7-hydroxy-indone derivatives and salts thereof
DE3781627T2 (de) * 1986-08-21 1993-05-06 Roussel Uclaf Indanderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, diese enthaltende pharmazeutische zusammensetzungen und erhaltene zwischenprodukte.
FR2640625B2 (fr) * 1986-08-21 1993-05-21 Roussel Uclaf Nouveaux composes optiquement actifs derives de l'indane, leur application comme medicaments et les compositions pharmaceutiques les renfermant
US4876269A (en) * 1986-09-10 1989-10-24 E. I. Du Pont De Nemours And Company Benoz-fused cycloalkane trans-1,2-diamine derivatives
JPH0542252Y2 (es) * 1986-11-11 1993-10-25
DK626889A (da) * 1988-12-16 1990-06-17 Roussel Uclaf Indanderivater, deres fremstilling samt laegemidler med indhold deraf

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3142619A (en) * 1961-07-24 1964-07-28 Ciba Geigy Corp Amino compounds
US3196181A (en) * 1963-03-01 1965-07-20 Ciba Geigy Corp Catalytic reduction of 2-oximinoindane to 2-amino-indane
DE1443664A1 (de) * 1964-09-10 1968-11-07 Albert Ag Chem Werke Verfahren zur Herstellung von pharmazeutisch wirksamen Derivaten des 2-Aminoindans
US3770828A (en) * 1967-10-20 1973-11-06 Mead Johnson & Co Substituted 3-phenylindan-1-one oximes
US3746495A (en) * 1971-06-01 1973-07-17 American Home Prod Anti-ulcer therapy

Also Published As

Publication number Publication date
EP0005821B1 (de) 1982-12-08
DK225279A (da) 1979-12-01
DE2964198D1 (en) 1983-01-13
EP0005821A1 (de) 1979-12-12
ES481102A0 (es) 1980-12-16
CA1109080A (en) 1981-09-15

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