ES8101539A1 - Un procedimiento para la preparacion de derivados de la in- danona. - Google Patents
Un procedimiento para la preparacion de derivados de la in- danona.Info
- Publication number
- ES8101539A1 ES8101539A1 ES481102A ES481102A ES8101539A1 ES 8101539 A1 ES8101539 A1 ES 8101539A1 ES 481102 A ES481102 A ES 481102A ES 481102 A ES481102 A ES 481102A ES 8101539 A1 ES8101539 A1 ES 8101539A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- lower alkyl
- medicaments containing
- indanamine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE LA INDANONA. CONSISTE EN SOMETER UN COMPUESTO HIDROXILIMINO DE FORMULA GENERAL (I) A UNA HIDROGENACION CATOLITICA EN PRESENCIA DE NIQUEL RAMY, OXIDO DE PT, CARBON PALADICO, EN UN DISOLVENTE ORGANICO, TAL COMO ACIDO ACETICO, ETANOL, METANOL. LA HIDROGENACION SE LLEVA A CABO BAJO PRESION DE 20 A 50 ATMOSFERAS Y A UNA TEMPERATURA DE 50 A 100GC, DURANTE UN TEMPO DE 2 A 10 HORAS. SE OBTIENE UN COMPUESTO (II), QUE PUEDE SER TRANSFORMADOR POR HIDROLISIS EN PRESENCIA DE NACH O KOH EN UN DISOLVENTE ORGANICO, TAL COMO ETILENGLICOL A REFLUJO MEDIANTE CALENTAMEITNO; LA REACCION DURA DE 5 A 48 HORAS. *FORMULA* ACTIVIDAD ANALGESICA.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6382178A JPS54157551A (en) | 1978-05-30 | 1978-05-30 | Indanamine derivative |
JP6382278A JPS54157552A (en) | 1978-05-30 | 1978-05-30 | Indanamine derivative |
JP54034349A JPS581102B2 (ja) | 1979-03-26 | 1979-03-26 | インダナミン誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8101539A1 true ES8101539A1 (es) | 1980-12-16 |
ES481102A0 ES481102A0 (es) | 1980-12-16 |
Family
ID=27288395
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES481102A Granted ES481102A0 (es) | 1978-05-30 | 1979-05-30 | Un procedimiento para la preparacion de derivados de la in- danona. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0005821B1 (es) |
CA (1) | CA1109080A (es) |
DE (1) | DE2964198D1 (es) |
DK (1) | DK225279A (es) |
ES (1) | ES481102A0 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2603035B1 (fr) * | 1986-08-21 | 1988-12-09 | Roussel Uclaf | Nouveaux derives de l'indane, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
FR2617480B1 (fr) * | 1987-07-03 | 1990-12-07 | Roussel Uclaf | Nouveaux derives de l'indane, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
CA1245663A (en) * | 1983-03-04 | 1988-11-29 | Yasuo Oshiro | 1-nitrogen containing-7-hydroxy-indone derivatives and salts thereof |
DE3781627T2 (de) * | 1986-08-21 | 1993-05-06 | Roussel Uclaf | Indanderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, diese enthaltende pharmazeutische zusammensetzungen und erhaltene zwischenprodukte. |
FR2640625B2 (fr) * | 1986-08-21 | 1993-05-21 | Roussel Uclaf | Nouveaux composes optiquement actifs derives de l'indane, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
US4876269A (en) * | 1986-09-10 | 1989-10-24 | E. I. Du Pont De Nemours And Company | Benoz-fused cycloalkane trans-1,2-diamine derivatives |
JPH0542252Y2 (es) * | 1986-11-11 | 1993-10-25 | ||
DK626889A (da) * | 1988-12-16 | 1990-06-17 | Roussel Uclaf | Indanderivater, deres fremstilling samt laegemidler med indhold deraf |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3142619A (en) * | 1961-07-24 | 1964-07-28 | Ciba Geigy Corp | Amino compounds |
US3196181A (en) * | 1963-03-01 | 1965-07-20 | Ciba Geigy Corp | Catalytic reduction of 2-oximinoindane to 2-amino-indane |
DE1443664A1 (de) * | 1964-09-10 | 1968-11-07 | Albert Ag Chem Werke | Verfahren zur Herstellung von pharmazeutisch wirksamen Derivaten des 2-Aminoindans |
US3770828A (en) * | 1967-10-20 | 1973-11-06 | Mead Johnson & Co | Substituted 3-phenylindan-1-one oximes |
US3746495A (en) * | 1971-06-01 | 1973-07-17 | American Home Prod | Anti-ulcer therapy |
-
1979
- 1979-05-28 CA CA328,466A patent/CA1109080A/en not_active Expired
- 1979-05-29 EP EP19790101641 patent/EP0005821B1/de not_active Expired
- 1979-05-29 DE DE7979101641T patent/DE2964198D1/de not_active Expired
- 1979-05-30 DK DK225279A patent/DK225279A/da not_active Application Discontinuation
- 1979-05-30 ES ES481102A patent/ES481102A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
EP0005821B1 (de) | 1982-12-08 |
DK225279A (da) | 1979-12-01 |
DE2964198D1 (en) | 1983-01-13 |
EP0005821A1 (de) | 1979-12-12 |
ES481102A0 (es) | 1980-12-16 |
CA1109080A (en) | 1981-09-15 |
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