ES551547A0 - Un procedimiento para la preparacion de dihidro piridin lactonas - Google Patents
Un procedimiento para la preparacion de dihidro piridin lactonasInfo
- Publication number
- ES551547A0 ES551547A0 ES551547A ES551547A ES551547A0 ES 551547 A0 ES551547 A0 ES 551547A0 ES 551547 A ES551547 A ES 551547A ES 551547 A ES551547 A ES 551547A ES 551547 A0 ES551547 A0 ES 551547A0
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- atoms
- chain
- optionally
- interrupted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/16—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrane Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Endoscopes (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polyesters Or Polycarbonates (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843410645 DE3410645A1 (de) | 1984-03-23 | 1984-03-23 | L-alkylsubstituierte 1,4-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8704174A1 ES8704174A1 (es) | 1987-03-16 |
ES551547A0 true ES551547A0 (es) | 1987-03-16 |
Family
ID=6231357
Family Applications (9)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES541309A Expired ES8607309A1 (es) | 1984-03-23 | 1985-03-15 | Dihidropiridinlactonas |
ES551545A Expired ES8702417A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551543A Expired ES8702415A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551547A Expired ES8704174A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551548A Expired ES8702418A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551541A Expired ES8702413A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551542A Expired ES8702414A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551544A Expired ES8702416A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551546A Expired ES8704173A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES541309A Expired ES8607309A1 (es) | 1984-03-23 | 1985-03-15 | Dihidropiridinlactonas |
ES551545A Expired ES8702417A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551543A Expired ES8702415A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
Family Applications After (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES551548A Expired ES8702418A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551541A Expired ES8702413A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551542A Expired ES8702414A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551544A Expired ES8702416A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
ES551546A Expired ES8704173A1 (es) | 1984-03-23 | 1986-01-31 | Un procedimiento para la preparacion de dihidro piridin lactonas |
Country Status (24)
Country | Link |
---|---|
US (1) | US5026714A (es) |
EP (1) | EP0158138B1 (es) |
JP (1) | JPS60209584A (es) |
KR (1) | KR850006439A (es) |
AT (1) | ATE37880T1 (es) |
AU (1) | AU569783B2 (es) |
CA (1) | CA1249270A (es) |
CS (1) | CS250681B2 (es) |
DD (1) | DD234424A5 (es) |
DE (2) | DE3410645A1 (es) |
DK (1) | DK158517C (es) |
EG (1) | EG16785A (es) |
ES (9) | ES8607309A1 (es) |
FI (1) | FI83651C (es) |
GR (1) | GR850719B (es) |
HU (1) | HU191167B (es) |
IL (1) | IL74659A (es) |
NO (1) | NO161259C (es) |
NZ (1) | NZ211512A (es) |
PH (3) | PH23826A (es) |
PL (1) | PL143884B1 (es) |
PT (1) | PT80146B (es) |
SU (1) | SU1319785A3 (es) |
ZA (1) | ZA852172B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3521761A1 (de) * | 1985-06-19 | 1987-01-02 | Bayer Ag | Neue 1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln |
US5162338A (en) * | 1986-01-11 | 1992-11-10 | Bayer Aktiengesellschaft | Circulation active 4-aminoaryldihydropryidine lactones |
DE3600596A1 (de) * | 1986-01-11 | 1987-07-16 | Bayer Ag | 4-aminoaryldihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
DE3629545A1 (de) * | 1986-08-30 | 1988-03-10 | Bayer Ag | Dihydropyridinverbindungen, verfahren zu ihrer herstellung und ihre verwendung |
DE3706204A1 (de) * | 1987-02-26 | 1988-09-08 | Bayer Ag | Benzylaminoaryl-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
GB8716971D0 (en) * | 1987-07-17 | 1987-08-26 | Pfizer Ltd | Therapeutic agents |
DE4430092A1 (de) * | 1994-08-25 | 1996-02-29 | Bayer Ag | 2,3-Cyclisch kondensierte 1,4-Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
WO2005025507A2 (en) * | 2003-09-10 | 2005-03-24 | Synta Phamaceuticals Corp. | Dihydropyridine compounds for treating or preventing metabolic disorders |
WO2021253180A1 (en) * | 2020-06-15 | 2021-12-23 | Novartis Ag | Methyl (r) -2- (fluoromethyl) -5-oxo-4-phenyl-4, 5, 6, 7-tetrahydro-1h-cyclopenta [b] pyridine-3-carboxylate and methyl (r) -2- (fluoromethyl) -5-oxo-4-phenyl-1, 4, 5, 7-tetrahydrofuro [3, 4-b] pyridine-3-carboxylate as cav1.2 activators |
KR20230022979A (ko) | 2020-06-16 | 2023-02-16 | 노파르티스 아게 | CAV1.2 활성제로서의 메틸 2-메틸-5-옥소-1,4,5,7-테트라하이드로푸로[3,4-b]피리딘-3-카르복실레이트 화합물 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2005116C3 (de) * | 1970-02-05 | 1980-02-14 | Bayer Ag, 5090 Leverkusen | Symmetrische 1,4-Dihydropyridin-3,5-dicarbonsäureester |
GB1552911A (en) * | 1975-07-02 | 1979-09-19 | Fujisawa Pharmaceutical Co | 1,4 dihydropyridine derivatives and the preparation thereof |
US4284634A (en) * | 1975-07-02 | 1981-08-18 | Fujisawa Pharmaceutical Co., Ltd. | 1,4-Dihydropyridine derivatives, and pharmaceutical method of the same |
US4253248A (en) | 1979-04-16 | 1981-03-03 | Cornish Judson E | Teaching machine apparatus |
DE3206671A1 (de) * | 1982-02-25 | 1983-09-01 | Bayer Ag, 5090 Leverkusen | Dihydropyridine mit positiv inotroper wirkung, neue verbindungen, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung |
DE3130041A1 (de) * | 1981-07-30 | 1983-02-17 | Bayer Ag, 5090 Leverkusen | Dihydropyridine mit positiv inotroper wirkung, neue verbindungen, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung |
NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
US4497808A (en) * | 1981-12-30 | 1985-02-05 | Ciba-Geigy Corporation | N-Oxide compounds useful in the treatment of cardiovascular ailments |
DE3209274A1 (de) * | 1982-03-13 | 1983-09-15 | Bayer Ag, 5090 Leverkusen | Pyridincarbonsaeureester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
DE3209276A1 (de) * | 1982-03-13 | 1983-09-15 | Bayer Ag, 5090 Leverkusen | Arzneimittel mit antihypoxischer und ischaemie-protektiver wirkung |
EP0111455A3 (de) * | 1982-12-10 | 1984-07-25 | Ciba-Geigy Ag | Ungesättigte Lactone |
DE3521761A1 (de) * | 1985-06-19 | 1987-01-02 | Bayer Ag | Neue 1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln |
DE3601226A1 (de) * | 1986-01-17 | 1987-07-23 | Bayer Ag | Dihydropyridinlactole, verfahren zur herstellung und ihre verwendung in arzneimitteln |
-
1984
- 1984-03-23 DE DE19843410645 patent/DE3410645A1/de not_active Withdrawn
-
1985
- 1985-02-28 PH PH31929A patent/PH23826A/en unknown
- 1985-03-06 NO NO850891A patent/NO161259C/no unknown
- 1985-03-12 DE DE8585102793T patent/DE3565541D1/de not_active Expired
- 1985-03-12 AT AT85102793T patent/ATE37880T1/de active
- 1985-03-12 EP EP85102793A patent/EP0158138B1/de not_active Expired
- 1985-03-15 SU SU853865401A patent/SU1319785A3/ru active
- 1985-03-15 ES ES541309A patent/ES8607309A1/es not_active Expired
- 1985-03-19 CS CS851923A patent/CS250681B2/cs unknown
- 1985-03-19 JP JP60053524A patent/JPS60209584A/ja active Pending
- 1985-03-20 HU HU851033A patent/HU191167B/hu not_active IP Right Cessation
- 1985-03-20 IL IL74659A patent/IL74659A/xx unknown
- 1985-03-20 EG EG182/85A patent/EG16785A/xx active
- 1985-03-20 NZ NZ211512A patent/NZ211512A/xx unknown
- 1985-03-21 GR GR850719A patent/GR850719B/el unknown
- 1985-03-21 KR KR1019850001857A patent/KR850006439A/ko not_active Application Discontinuation
- 1985-03-21 DD DD85274322A patent/DD234424A5/de not_active IP Right Cessation
- 1985-03-21 PT PT80146A patent/PT80146B/pt not_active IP Right Cessation
- 1985-03-21 FI FI851143A patent/FI83651C/fi not_active IP Right Cessation
- 1985-03-21 CA CA000477087A patent/CA1249270A/en not_active Expired
- 1985-03-22 DK DK131685A patent/DK158517C/da not_active IP Right Cessation
- 1985-03-22 ZA ZA852172A patent/ZA852172B/xx unknown
- 1985-03-22 PL PL1985252522A patent/PL143884B1/pl unknown
- 1985-03-25 AU AU40449/85A patent/AU569783B2/en not_active Ceased
-
1986
- 1986-01-31 ES ES551545A patent/ES8702417A1/es not_active Expired
- 1986-01-31 ES ES551543A patent/ES8702415A1/es not_active Expired
- 1986-01-31 ES ES551547A patent/ES8704174A1/es not_active Expired
- 1986-01-31 ES ES551548A patent/ES8702418A1/es not_active Expired
- 1986-01-31 ES ES551541A patent/ES8702413A1/es not_active Expired
- 1986-01-31 ES ES551542A patent/ES8702414A1/es not_active Expired
- 1986-01-31 ES ES551544A patent/ES8702416A1/es not_active Expired
- 1986-01-31 ES ES551546A patent/ES8704173A1/es not_active Expired
- 1986-03-18 PH PH33544A patent/PH23455A/en unknown
-
1987
- 1987-07-23 PH PH35576A patent/PH24347A/en unknown
-
1989
- 1989-11-13 US US07/436,157 patent/US5026714A/en not_active Expired - Fee Related
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19960603 |