ES514633A0 - "metodo de preparar compuestos esteroidicos antiinflamatorios". - Google Patents
"metodo de preparar compuestos esteroidicos antiinflamatorios".Info
- Publication number
- ES514633A0 ES514633A0 ES514633A ES514633A ES514633A0 ES 514633 A0 ES514633 A0 ES 514633A0 ES 514633 A ES514633 A ES 514633A ES 514633 A ES514633 A ES 514633A ES 514633 A0 ES514633 A0 ES 514633A0
- Authority
- ES
- Spain
- Prior art keywords
- preparing anti
- steroid compounds
- inflammatory steroid
- inflammatory
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16845380A | 1980-07-10 | 1980-07-10 | |
US26578581A | 1981-05-21 | 1981-05-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES514633A0 true ES514633A0 (es) | 1983-06-16 |
ES8306767A1 ES8306767A1 (es) | 1983-06-16 |
Family
ID=26864131
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES504340A Granted ES504340A0 (es) | 1980-07-10 | 1981-07-10 | Procedimiento de preparar esteroides e intermedios de este- roides antiinflamatorios |
ES514633A Expired ES8306767A1 (es) | 1980-07-10 | 1982-08-02 | "metodo de preparar compuestos esteroidicos antiinflamatorios". |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES504340A Granted ES504340A0 (es) | 1980-07-10 | 1981-07-10 | Procedimiento de preparar esteroides e intermedios de este- roides antiinflamatorios |
Country Status (17)
Country | Link |
---|---|
KR (2) | KR860000266B1 (es) |
AT (1) | AT379816B (es) |
AU (1) | AU540898B2 (es) |
CA (1) | CA1174667A (es) |
CH (1) | CH648856A5 (es) |
DE (1) | DE3126732C2 (es) |
DK (1) | DK165837C (es) |
ES (2) | ES504340A0 (es) |
FI (1) | FI71748C (es) |
FR (1) | FR2486529A1 (es) |
GB (1) | GB2079755B (es) |
IT (1) | IT1205446B (es) |
NL (1) | NL192343C (es) |
NO (1) | NO163285C (es) |
PH (1) | PH25874A (es) |
PT (1) | PT73348B (es) |
SE (1) | SE449106B (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2137206B (en) * | 1980-02-15 | 1985-04-03 | Glaxo Group Ltd | Androstane 17-carbothioc acid derivatives |
JPS6041607A (ja) * | 1983-08-12 | 1985-03-05 | Otsuka Pharmaceut Co Ltd | 軟膏基剤 |
SE8501693D0 (sv) * | 1985-04-04 | 1985-04-04 | Draco Ab | Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters |
IL78144A0 (en) * | 1985-04-04 | 1986-07-31 | Draco Ab | Novel androstane-17beta-carboxylic acid esters |
ATE90355T1 (de) * | 1987-10-13 | 1993-06-15 | Nicholas S Bodor | Weiche steroide mit anti-entzuendungswirkung. |
DE4025342A1 (de) * | 1990-08-10 | 1992-02-13 | Hoechst Ag | In 17-stellung substituierte corticoid-17-alkylcarbonate, verfahren zu deren herstellung und diese enthaltende arzneimittel |
EP0998484B1 (en) * | 1997-06-30 | 2004-03-03 | Glaxo Group Limited | Method of identifying compounds having reduced systemic effects |
AR032471A1 (es) | 2000-08-05 | 2003-11-12 | Glaxo Group Ltd | Derivado de androstano y solvatos del mismo, su uso para la fabricacion de medicamentos, composiciones farmaceuticas que los comprenden, procesos para preparar tales derivados, intermediarios utiles en la preparacion de tales derivados, procesos para preparar tales intermediarios, y compuestos inter |
US6858596B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivative |
US6759398B2 (en) | 2000-08-05 | 2004-07-06 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative |
GB0019172D0 (en) | 2000-08-05 | 2000-09-27 | Glaxo Group Ltd | Novel compounds |
US6750210B2 (en) | 2000-08-05 | 2004-06-15 | Smithkline Beecham Corporation | Formulation containing novel anti-inflammatory androstane derivative |
US6787532B2 (en) | 2000-08-05 | 2004-09-07 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivatives |
US6777399B2 (en) | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
US6858593B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
US6777400B2 (en) | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
UA77656C2 (en) | 2001-04-07 | 2007-01-15 | Glaxo Group Ltd | S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent |
GB2389530B (en) | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
UA82323C2 (uk) * | 2002-08-09 | 2008-04-10 | Меда Фарма Гмбх & Ко. Кг | Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань |
GB0316290D0 (en) | 2003-07-11 | 2003-08-13 | Glaxo Group Ltd | Novel compounds |
JP5281291B2 (ja) | 2005-01-10 | 2013-09-04 | グラクソ グループ リミテッド | 新規化合物 |
TWI374147B (en) * | 2006-01-27 | 2012-10-11 | Sun Pharma Advance Res Company Ltd | Novel 11β-hydroxyandrosta-4-ene-3-ones |
US7687484B2 (en) * | 2006-05-25 | 2010-03-30 | Bodor Nicholas S | Transporter enhanced corticosteroid activity |
US7691811B2 (en) * | 2006-05-25 | 2010-04-06 | Bodor Nicholas S | Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye |
CN101942001B (zh) * | 2010-08-24 | 2013-02-06 | 山东省医药工业研究所 | 一种氯替泼诺的提纯方法 |
CN103183714A (zh) * | 2011-12-29 | 2013-07-03 | 山东方明药业集团股份有限公司 | 一种氯替泼诺的合成方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1384372A (en) * | 1971-01-20 | 1975-02-19 | Glaxo Lab Ltd | Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids |
GB1438940A (en) * | 1972-07-19 | 1976-06-09 | Glaxo Lab Ltd | 17beta-haloalkoxycarbonyl-17alpha-oxysteroids |
GB1514476A (en) * | 1974-08-30 | 1978-06-14 | Glaxo Lab Ltd | Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates |
DE2735110A1 (de) * | 1977-08-04 | 1979-02-15 | Hoechst Ag | Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung |
IT1114534B (it) * | 1978-02-08 | 1986-01-27 | Glaxo Group Ltd | Steroide anti-infiammatorio della serie dell'androstano composizioni che lo contengono e procedimento per produrlo |
US4188385A (en) * | 1978-04-05 | 1980-02-12 | Syntex (U.S.A.) Inc. | Thioetianic acid derivatives |
DE2817988A1 (de) * | 1978-04-25 | 1979-11-08 | Hoechst Ag | Corticoid 17-alkylcarbonate und verfahren zu deren herstellung |
-
1981
- 1981-07-02 SE SE8104132A patent/SE449106B/sv not_active IP Right Cessation
- 1981-07-06 AU AU72591/81A patent/AU540898B2/en not_active Expired
- 1981-07-06 GB GB8120864A patent/GB2079755B/en not_active Expired
- 1981-07-07 DE DE3126732A patent/DE3126732C2/de not_active Expired
- 1981-07-08 PH PH25877A patent/PH25874A/en unknown
- 1981-07-08 CH CH4497/81A patent/CH648856A5/de not_active IP Right Cessation
- 1981-07-08 CA CA000381293A patent/CA1174667A/en not_active Expired
- 1981-07-08 DK DK302181A patent/DK165837C/da not_active IP Right Cessation
- 1981-07-09 IT IT05186/81A patent/IT1205446B/it active
- 1981-07-09 FI FI812175A patent/FI71748C/fi not_active IP Right Cessation
- 1981-07-09 NO NO812344A patent/NO163285C/no unknown
- 1981-07-10 NL NL8103315A patent/NL192343C/nl not_active IP Right Cessation
- 1981-07-10 FR FR8113607A patent/FR2486529A1/fr active Granted
- 1981-07-10 AT AT0307081A patent/AT379816B/de not_active IP Right Cessation
- 1981-07-10 PT PT73348A patent/PT73348B/pt unknown
- 1981-07-10 ES ES504340A patent/ES504340A0/es active Granted
- 1981-07-10 KR KR1019810002502A patent/KR860000266B1/ko active
-
1982
- 1982-08-02 ES ES514633A patent/ES8306767A1/es not_active Expired
-
1984
- 1984-09-25 KR KR1019840005874A patent/KR860000452B1/ko not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20030211 |