ES493915A0 - Un procedimiento para preparar una sal de tetrahidropiridi- nio - Google Patents

Un procedimiento para preparar una sal de tetrahidropiridi- nio

Info

Publication number
ES493915A0
ES493915A0 ES493915A ES493915A ES493915A0 ES 493915 A0 ES493915 A0 ES 493915A0 ES 493915 A ES493915 A ES 493915A ES 493915 A ES493915 A ES 493915A ES 493915 A0 ES493915 A0 ES 493915A0
Authority
ES
Spain
Prior art keywords
tetrahydropiridium
salt
preparing
procedure
tetrahydropiridium salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES493915A
Other languages
English (en)
Other versions
ES8200664A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES493915A0 publication Critical patent/ES493915A0/es
Publication of ES8200664A1 publication Critical patent/ES8200664A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES493915A 1978-11-29 1980-07-31 Un procedimiento para preparar una sal de tetrahidropiridi- nio Expired ES8200664A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/965,137 US4284635A (en) 1978-11-29 1978-11-29 Analgesic 1,2,4,5-tetra-alkyl-4-arylpiperidines

Publications (2)

Publication Number Publication Date
ES493915A0 true ES493915A0 (es) 1981-11-16
ES8200664A1 ES8200664A1 (es) 1981-11-16

Family

ID=25509504

Family Applications (2)

Application Number Title Priority Date Filing Date
ES486425A Expired ES8101551A1 (es) 1978-11-29 1979-11-28 Un procedimiento para preparar nuevas 4-arilpiperinas.
ES493915A Expired ES8200664A1 (es) 1978-11-29 1980-07-31 Un procedimiento para preparar una sal de tetrahidropiridi- nio

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES486425A Expired ES8101551A1 (es) 1978-11-29 1979-11-28 Un procedimiento para preparar nuevas 4-arilpiperinas.

Country Status (26)

Country Link
US (1) US4284635A (es)
EP (1) EP0013078A3 (es)
JP (1) JPS5573657A (es)
KR (1) KR830001214A (es)
AR (1) AR224138A1 (es)
AT (1) ATA750879A (es)
AU (1) AU529136B2 (es)
BE (1) BE880220A (es)
CA (1) CA1121357A (es)
DD (1) DD147537A5 (es)
DK (1) DK504979A (es)
EG (1) EG14137A (es)
ES (2) ES8101551A1 (es)
FI (1) FI793663A (es)
FR (2) FR2442836A1 (es)
GB (1) GB2038812B (es)
GR (1) GR72292B (es)
HU (1) HU178532B (es)
IL (1) IL58793A0 (es)
IT (1) IT1126406B (es)
LU (1) LU81923A1 (es)
PH (1) PH15420A (es)
PL (1) PL123672B1 (es)
PT (1) PT70486A (es)
SU (1) SU967275A3 (es)
ZA (1) ZA796336B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5212183A (en) * 1981-11-14 1993-05-18 Basf Aktiengesellschaft 4-(p-tert.-butylphenyl)-3-methylpiperidines substituted at the nitrogen, their quaternary salts and their use as fungicides
US4485109A (en) * 1982-05-07 1984-11-27 E. I. Du Pont De Nemours And Company 4-Aryl-4-piperidinecarbinols
US4581456A (en) * 1983-09-21 1986-04-08 Eli Lilly And Company Processes for preparing picenadol precursors and novel intermediates thereof
ZW10287A1 (en) * 1986-07-15 1988-01-13 Hoffmann La Roche Tetrahydronaphthaline and indane derivatives
EP0299549A3 (en) * 1987-07-09 1989-02-08 Duphar International Research B.V Tertiary 2,5-dialkyl-3-phenyl-piperidine derivatives having opiate-antagonistic activity
CA1337418C (en) * 1988-03-28 1995-10-24 Engelbert Ciganek 4-aryl-4-piperiding (or pyrrolidine or hexahydroazepine) carbinols and heterocyclic analogs thereof
US5136040A (en) * 1991-02-26 1992-08-04 Eli Lilly And Company Preparation of substituted tetrahydropyridines
US5270328A (en) * 1991-03-29 1993-12-14 Eli Lilly And Company Peripherally selective piperidine opioid antagonists
US5250542A (en) * 1991-03-29 1993-10-05 Eli Lilly And Company Peripherally selective piperidine carboxylate opioid antagonists
US5159081A (en) * 1991-03-29 1992-10-27 Eli Lilly And Company Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists
GB9912416D0 (en) * 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy
GB9912411D0 (en) 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy
GB9912413D0 (en) 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy
GB9912415D0 (en) 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy
GB9912417D0 (en) 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy
GB9912410D0 (en) 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2892842A (en) * 1959-06-30 Their preparation
US2956058A (en) * 1957-08-19 1960-10-11 Lilly Co Eli Novel substituted piperidines and pyrrolidines
US3043845A (en) * 1958-12-29 1962-07-10 Abbott Lab Phenylmethylpiperidine derivatives
US3080372A (en) * 1960-03-25 1963-03-05 Res Lab Dr C Janssen 1-aroylalkyl-4-arylpiperidine derivatives
NL123743C (es) * 1963-09-18
BE720927A (es) * 1967-09-27 1969-03-03
US3936468A (en) * 1969-10-27 1976-02-03 Sumitomo Chemical Company, Ltd. Phenylbutanol derivatives
GB1403942A (en) * 1973-04-05 1975-08-28 Ciba Geigy Ag Piperidine derivatives
AR206937A1 (es) * 1974-09-06 1976-08-31 Lilly Co Eli Procedimiento para preparar compuestos de 1-sustituido-4-alquil-4-fenil-piperidina
US4115400A (en) * 1976-05-27 1978-09-19 Eli Lilly And Company 1-Azoniabicyclo[3.1.0]hexanes
ZA777356B (en) * 1976-12-17 1979-01-31 Rohm & Haas Arthropod repellents

Also Published As

Publication number Publication date
FI793663A (fi) 1980-05-30
LU81923A1 (fr) 1980-04-22
EP0013078A3 (en) 1980-10-01
JPS5573657A (en) 1980-06-03
IT1126406B (it) 1986-05-21
ATA750879A (de) 1983-03-15
FR2442836B1 (es) 1983-07-29
EP0013078A2 (en) 1980-07-09
GB2038812A (en) 1980-07-30
DD147537A5 (de) 1981-04-08
IL58793A0 (en) 1980-02-29
SU967275A3 (ru) 1982-10-15
US4284635A (en) 1981-08-18
EG14137A (en) 1983-09-30
FR2442836A1 (fr) 1980-06-27
GR72292B (es) 1983-10-17
HU178532B (en) 1982-05-28
AU5310079A (en) 1980-05-29
AR224138A1 (es) 1981-10-30
ZA796336B (en) 1981-06-24
FR2453154B1 (es) 1983-05-27
PL123672B1 (en) 1982-11-30
AU529136B2 (en) 1983-05-26
IT7927614A0 (it) 1979-11-27
GB2038812B (en) 1983-01-06
ES8200664A1 (es) 1981-11-16
CA1121357A (en) 1982-04-06
BE880220A (fr) 1980-05-23
FR2453154A1 (fr) 1980-10-31
PL219885A1 (es) 1980-12-01
KR830001214A (ko) 1983-04-29
ES486425A0 (es) 1980-12-16
PT70486A (en) 1979-12-01
PH15420A (en) 1983-01-07
DK504979A (da) 1980-05-30
ES8101551A1 (es) 1980-12-16

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