ES472297A1 - Procedimiento para la preparacion de 1-metil-isoguanosina - Google Patents
Procedimiento para la preparacion de 1-metil-isoguanosinaInfo
- Publication number
- ES472297A1 ES472297A1 ES472297A ES472297A ES472297A1 ES 472297 A1 ES472297 A1 ES 472297A1 ES 472297 A ES472297 A ES 472297A ES 472297 A ES472297 A ES 472297A ES 472297 A1 ES472297 A1 ES 472297A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- methylisoguanosin
- intermediates
- processes
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se ha descubierto que la 1-metil-isoguanosina está contenida en bajas cantidades en organismos marinos, particularmente en esponjas pertenecientes al género Tedania, que pueden recogerse en las costas marítimas australianas. Por consiguiente, el invento se refiere en un aspecto al aislamiento de 1-metil-isoguanosina de fuentes naturales, particularmente de organismos marinos, especialmente esponjas del género Tedania. Por consiguiente constituye una característica adicional del presente invento la 1-metil-isoguanosina en forma sustancialmente pura, o sea libre de sub-productos que se encuentran en estado natural. La 1-metil-isoguanosina puede aislarse de la fuente natural, por ejemplo de esponjas, por ejemplo mediante extracción con DMSO, agua y/o un disolvente hidroxílico orgánico, tal como un alcanol inferior, por ejemplo metanol o etanol.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU77910 | 1977-08-03 | ||
US87676978A | 1978-02-10 | 1978-02-10 | |
US05/876,768 US4148993A (en) | 1978-02-10 | 1978-02-10 | Process to produce 1-methyl isoguanosine |
GB7826761A GB2001955A (en) | 1977-08-03 | 1978-06-13 | 1-Methyl-isoguanine |
Publications (1)
Publication Number | Publication Date |
---|---|
ES472297A1 true ES472297A1 (es) | 1979-02-16 |
Family
ID=27449076
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES472297A Expired ES472297A1 (es) | 1977-08-03 | 1978-08-02 | Procedimiento para la preparacion de 1-metil-isoguanosina |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0000770A3 (es) |
JP (1) | JPS5448794A (es) |
AU (1) | AU3840678A (es) |
DE (1) | DE2833887A1 (es) |
DK (1) | DK343578A (es) |
ES (1) | ES472297A1 (es) |
FI (1) | FI782298A (es) |
FR (1) | FR2399441A1 (es) |
IL (1) | IL55240A0 (es) |
IT (1) | IT1202760B (es) |
MC (1) | MC1200A1 (es) |
NO (1) | NO782648L (es) |
PT (1) | PT68377A (es) |
SE (1) | SE7808350L (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108864234B (zh) * | 2018-07-06 | 2020-06-26 | 厦门医学院 | 一种从皱瘤海鞘中分离肌苷的方法 |
-
1978
- 1978-07-20 FI FI782298A patent/FI782298A/fi not_active Application Discontinuation
- 1978-07-27 AU AU38406/78A patent/AU3840678A/en active Pending
- 1978-07-28 IL IL55240A patent/IL55240A0/xx unknown
- 1978-07-31 MC MC781317A patent/MC1200A1/xx unknown
- 1978-08-01 JP JP9323178A patent/JPS5448794A/ja active Pending
- 1978-08-02 ES ES472297A patent/ES472297A1/es not_active Expired
- 1978-08-02 DK DK343578A patent/DK343578A/da unknown
- 1978-08-02 DE DE19782833887 patent/DE2833887A1/de not_active Withdrawn
- 1978-08-02 PT PT68377A patent/PT68377A/pt unknown
- 1978-08-02 SE SE7808350A patent/SE7808350L/xx unknown
- 1978-08-02 NO NO782648A patent/NO782648L/no unknown
- 1978-08-02 EP EP78100579A patent/EP0000770A3/de not_active Withdrawn
- 1978-08-03 IT IT26445/78A patent/IT1202760B/it active
- 1978-08-03 FR FR7822976A patent/FR2399441A1/fr active Pending
Also Published As
Publication number | Publication date |
---|---|
PT68377A (en) | 1978-09-01 |
AU3840678A (en) | 1980-01-31 |
IL55240A0 (en) | 1978-09-29 |
EP0000770A2 (de) | 1979-02-21 |
IT1202760B (it) | 1989-02-09 |
MC1200A1 (fr) | 1979-03-19 |
DK343578A (da) | 1979-02-04 |
EP0000770A3 (de) | 1979-06-13 |
SE7808350L (sv) | 1979-02-04 |
JPS5448794A (en) | 1979-04-17 |
FR2399441A1 (fr) | 1979-03-02 |
NO782648L (no) | 1979-02-06 |
DE2833887A1 (de) | 1979-02-22 |
FI782298A (fi) | 1979-02-04 |
IT7826445A0 (it) | 1978-08-03 |
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