ES464642A1 - Preparations of 3-n-pyrrolidino-4-phenoxy-5-sulphamyl-benzolc acid and process for their manufacture - Google Patents

Preparations of 3-n-pyrrolidino-4-phenoxy-5-sulphamyl-benzolc acid and process for their manufacture

Info

Publication number
ES464642A1
ES464642A1 ES464642A ES464642A ES464642A1 ES 464642 A1 ES464642 A1 ES 464642A1 ES 464642 A ES464642 A ES 464642A ES 464642 A ES464642 A ES 464642A ES 464642 A1 ES464642 A1 ES 464642A1
Authority
ES
Spain
Prior art keywords
pyrrolidino
phenoxy
preparations
active substance
sulphamyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES464642A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES464642A1 publication Critical patent/ES464642A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Process for the preparation of forms of preparations of 3-N-pyrrolidino-4-phenoxy-5-sulfamylbenzoic acid with delayed release characterized in that particles containing active substance are provided with coatings that dissolve in a weakly acidic medium which lead to the release of active substance in vitro in the passage element according to dibbernal for 75 minutes in a buffer solution of ph 55a not more than 25% of the content of active substance. (Machine-translation by Google Translate, not legally binding)
ES464642A 1976-12-07 1977-12-01 Preparations of 3-n-pyrrolidino-4-phenoxy-5-sulphamyl-benzolc acid and process for their manufacture Expired ES464642A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762655331 DE2655331A1 (en) 1976-12-07 1976-12-07 PREPARATION FORMS OF 3-N-PYRROLIDINO-4-PHENOXY-5-SULFAMYL-BENZOESIC ACID AND METHOD FOR THE PRODUCTION THEREOF

Publications (1)

Publication Number Publication Date
ES464642A1 true ES464642A1 (en) 1978-09-01

Family

ID=5994862

Family Applications (1)

Application Number Title Priority Date Filing Date
ES464642A Expired ES464642A1 (en) 1976-12-07 1977-12-01 Preparations of 3-n-pyrrolidino-4-phenoxy-5-sulphamyl-benzolc acid and process for their manufacture

Country Status (15)

Country Link
JP (1) JPS5372815A (en)
AT (1) AT355216B (en)
AU (1) AU513409B2 (en)
BE (1) BE861608A (en)
DE (1) DE2655331A1 (en)
DK (1) DK542877A (en)
ES (1) ES464642A1 (en)
FR (1) FR2373280A1 (en)
GB (1) GB1569018A (en)
IE (1) IE46005B1 (en)
IL (1) IL53539A0 (en)
NL (1) NL7713392A (en)
NZ (1) NZ185855A (en)
PT (1) PT67370B (en)
ZA (1) ZA777204B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0243891B1 (en) * 1986-04-29 1991-08-14 Hoechst-Roussel Pharmaceuticals Incorporated A laminar structure for administering a chemical at a controlled release rate
SE460947B (en) * 1986-08-26 1989-12-11 Lejus Medical Ab A MULTIPLE-UNIT DOS COMPOSITION OF L-DOPA
DK0812320T3 (en) * 1995-02-22 2003-04-14 Aventis Pharma Ltd Amorphous pyrethanide, polymorphic forms thereof, process for their preparation and their use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE33874B1 (en) * 1968-12-24 1974-11-27 Leo Pharm Prod Ltd New sulphamyl-benzoic acid derivatives

Also Published As

Publication number Publication date
PT67370A (en) 1978-01-01
DE2655331A1 (en) 1978-06-08
BE861608A (en) 1978-06-07
IL53539A0 (en) 1978-03-10
IE46005B1 (en) 1983-01-26
NL7713392A (en) 1978-06-09
ATA873777A (en) 1979-07-15
NZ185855A (en) 1979-10-25
GB1569018A (en) 1980-06-11
AU513409B2 (en) 1980-11-27
PT67370B (en) 1979-09-20
AT355216B (en) 1980-02-25
ZA777204B (en) 1978-10-25
FR2373280A1 (en) 1978-07-07
DK542877A (en) 1978-06-08
AU3127477A (en) 1979-06-14
FR2373280B1 (en) 1980-06-20
IE46005L (en) 1978-06-07
JPS5372815A (en) 1978-06-28

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