ES464149A1 - Piperidine derivatives - Google Patents

Piperidine derivatives

Info

Publication number
ES464149A1
ES464149A1 ES464149A ES464149A ES464149A1 ES 464149 A1 ES464149 A1 ES 464149A1 ES 464149 A ES464149 A ES 464149A ES 464149 A ES464149 A ES 464149A ES 464149 A1 ES464149 A1 ES 464149A1
Authority
ES
Spain
Prior art keywords
group
cycloalkyl
derived
carbon atoms
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES464149A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anphar SA
Original Assignee
Anphar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anphar SA filed Critical Anphar SA
Publication of ES464149A1 publication Critical patent/ES464149A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedure for the preparation of piperidine derivatives of general formula ** (Formula) where R represents a halogen atom or a hydroxy or lower alkynyloxy group, or a lower acyloxy group in which the acyl group is derived from a carboxylic acid or an aralkyloxy group R1 and R2 equal or different from each other, are halogen, sulfonamido, amino, lower alkylamino, dialkylamino lower, lower alkylsulfonyl, lower alkylsulfonamido, or lower acylamino group in which the acyl group is derived from a carboxylic acid, including trifluoroacetic acid with the group represented by R1 in. 3 or 4 position of the benzene ring, except that R1 and R2 do not represent hydrogen atoms at the same time; R3 represents a hydrogen atom, a lower alkyl or lower alkenyl group, a phenyl group or a cycloalkyl or cycloalkenyl group with 3 to 7 ring carbon atoms; R4 represents a cycloalkyl or cycloalkenyl group of 3 to 7 ring carbon atoms, an aroyl, aryl or heterocyclic group; R5, R6 and R7 each represent a hydrogen atom, a lower alkyl, lower alkenyl or benzyl group, and W represents a single bond or a lower alkylene or lower alkenylene group. (Machine-translation by Google Translate, not legally binding)
ES464149A 1976-11-16 1977-11-15 Piperidine derivatives Expired ES464149A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4773876A GB1575310A (en) 1976-11-16 1976-11-16 Piperidine derivatives

Publications (1)

Publication Number Publication Date
ES464149A1 true ES464149A1 (en) 1978-09-01

Family

ID=10446083

Family Applications (2)

Application Number Title Priority Date Filing Date
ES464148A Expired ES464148A1 (en) 1976-11-16 1977-11-15 Piperidine derivatives
ES464149A Expired ES464149A1 (en) 1976-11-16 1977-11-15 Piperidine derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES464148A Expired ES464148A1 (en) 1976-11-16 1977-11-15 Piperidine derivatives

Country Status (5)

Country Link
JP (1) JPS5387364A (en)
DE (1) DE2751181A1 (en)
ES (2) ES464148A1 (en)
FR (1) FR2370731A1 (en)
GB (1) GB1575310A (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3003843A1 (en) * 1980-02-02 1981-08-13 Chemische Werke Hüls AG, 4370 Marl METHOD FOR PRODUCING 4-AMINO-2,2,6,6-TETRAMETHYL PIPERIDINE
US4962115A (en) * 1981-10-01 1990-10-09 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US5057525A (en) * 1981-10-01 1991-10-15 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl) benzamide derivatives
US5137896A (en) * 1981-10-01 1992-08-11 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)benzamide derivatives
FR2534255B1 (en) * 1982-10-11 1985-07-12 Delalande Sa NOVEL 4-AROYLAMINO PIPERIDINE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC APPLICATION THEREOF
FR2546169B1 (en) * 1983-05-20 1986-03-21 Delalande Sa N-OXIDES OF AMINOCYCLIC DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS
FI95572C (en) * 1987-06-22 1996-02-26 Eisai Co Ltd Process for the preparation of a medicament useful as a piperidine derivative or its pharmaceutical salt
US6517811B2 (en) 1993-05-06 2003-02-11 Research Corporation Technologies, Inc. Compounds for cancer imaging and therapy
JP3235913B2 (en) * 1993-07-30 2001-12-04 エーザイ株式会社 Aminobenzoic acid derivative
AU1057101A (en) * 1999-11-17 2001-05-30 Kissei Pharmaceutical Co. Ltd. Hydroxyethoxybenzamide derivatives and drugs containing the same
TW200800953A (en) 2002-10-30 2008-01-01 Theravance Inc Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine
WO2004046110A1 (en) * 2002-11-15 2004-06-03 Yamanouchi Pharmaceutical Co., Ltd. Antagonist to melanin-concentrating hormone receptor
WO2005007645A1 (en) 2003-07-11 2005-01-27 Theravance, Inc. Substituted 4-amino-1-benzylpiperidine compounds
US8673920B2 (en) 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9073882B2 (en) 2010-10-27 2015-07-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9056859B2 (en) 2010-10-29 2015-06-16 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2744499B1 (en) 2011-08-19 2016-09-28 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
TW201317213A (en) 2011-09-16 2013-05-01 Merck Sharp & Dohme Inhibitors of the renal outer medullary potassium channel
US8999991B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2013062892A1 (en) 2011-10-25 2013-05-02 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2773206B1 (en) 2011-10-31 2018-02-21 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2013066718A2 (en) 2011-10-31 2013-05-10 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9139585B2 (en) 2011-10-31 2015-09-22 Merck Sharp & Dohme Corp. Inhibitors of the Renal Outer Medullary Potassium channel
WO2013090271A1 (en) 2011-12-16 2013-06-20 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
AR092031A1 (en) 2012-07-26 2015-03-18 Merck Sharp & Dohme INHIBITORS OF THE EXTERNAL RENAL MEDULAR POTASSIUM CHANNEL
EP2925322B1 (en) 2012-11-29 2018-10-24 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2934533B1 (en) 2012-12-19 2017-11-15 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9604998B2 (en) 2013-02-18 2017-03-28 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2968288B1 (en) 2013-03-15 2018-07-04 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9751881B2 (en) 2013-07-31 2017-09-05 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2016127358A1 (en) 2015-02-12 2016-08-18 Merck Sharp & Dohme Corp. Inhibitors of renal outer medullary potassium channel

Also Published As

Publication number Publication date
DE2751181A1 (en) 1978-05-24
JPS5387364A (en) 1978-08-01
FR2370731A1 (en) 1978-06-09
FR2370731B1 (en) 1980-05-16
GB1575310A (en) 1980-09-17
ES464148A1 (en) 1978-09-01

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