ES457513A1 - Procedimiento para la preparacion de 2-(2,2-diciclohexiletilpiperidina. - Google Patents
Procedimiento para la preparacion de 2-(2,2-diciclohexiletilpiperidina.Info
- Publication number
- ES457513A1 ES457513A1 ES457513A ES457513A ES457513A1 ES 457513 A1 ES457513 A1 ES 457513A1 ES 457513 A ES457513 A ES 457513A ES 457513 A ES457513 A ES 457513A ES 457513 A1 ES457513 A1 ES 457513A1
- Authority
- ES
- Spain
- Prior art keywords
- dicyclohexylethyl
- piperidine
- preparing
- diphenylethenyl
- pyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Procedimiento para la preparación de 2-(2,2-diciclohexiletil)piperidina, caracterizado porque comprende la operación de reducir una mezcla de 2-(2,2difenilatenil)piridina o una de sus sales, en un disolvente, seleccionado del grupo consistente en ácido acético o un alcanol inferior teniendo de 1 a 4 átomos de carbono con hidrógeno a una presión de 14 a 140 atmósferas y a una temperatura desde 90 a 200ºC, en presencia de un catalizador soportador de rodio, porque dicho catalizador está presente en una proporción de por lo menos 0,15 partes de rodio a 100 partes de dicha 2-(2,2-difeniletenil)piridina y recuperando la 2-(2,2-diciclohexiletil)piperidina obtenido por ello.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/677,036 US4191828A (en) | 1976-04-14 | 1976-04-14 | Process for preparing 2-(2,2-dicyclohexylethyl)piperidine |
Publications (1)
Publication Number | Publication Date |
---|---|
ES457513A1 true ES457513A1 (es) | 1978-03-16 |
Family
ID=24717044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES457513A Expired ES457513A1 (es) | 1976-04-14 | 1977-04-04 | Procedimiento para la preparacion de 2-(2,2-diciclohexiletilpiperidina. |
Country Status (19)
Country | Link |
---|---|
US (1) | US4191828A (es) |
JP (1) | JPS52125173A (es) |
AR (1) | AR211572A1 (es) |
AU (1) | AU506052B2 (es) |
BE (1) | BE853433A (es) |
CA (1) | CA1066288A (es) |
CH (1) | CH629189A5 (es) |
DE (1) | DE2714081A1 (es) |
DK (1) | DK156647C (es) |
ES (1) | ES457513A1 (es) |
FR (1) | FR2348199A1 (es) |
GB (1) | GB1513713A (es) |
IE (1) | IE44619B1 (es) |
IL (1) | IL51551A (es) |
NL (1) | NL7702823A (es) |
NO (1) | NO149845C (es) |
PH (1) | PH11876A (es) |
SE (1) | SE436201B (es) |
ZA (1) | ZA771115B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR79426B (es) * | 1982-11-16 | 1984-10-22 | Lilly Co Eli | |
DE4439822A1 (de) * | 1994-11-08 | 1996-08-29 | Bayer Ag | Verfahren zur Herstellung von Benzyl-piperidylmethyl-indanonen |
US6080863A (en) * | 1999-05-26 | 2000-06-27 | Phillips Petroleum Company | Process for producing piperidine |
ITMI20042415A1 (it) * | 2004-12-17 | 2005-03-17 | Clariant Lsm Italia Spa | Sintesi di alfa-aril-alfa-piperid-2-il-acetammidi e loro idrolisi acida |
SI2007752T1 (sl) | 2006-03-31 | 2010-12-31 | Janssen Pharmaceutica Nv | Benzoimidazol-2-il pirimidini in pirazini kot modulatorji histamin H4 receptorja |
US9371311B2 (en) | 2008-06-30 | 2016-06-21 | Janssen Pharmaceutica Nv | Benzoimidazol-2-yl pyrimidine derivatives |
ME02154B (me) | 2008-06-30 | 2015-10-20 | Janssen Pharmaceutica Nv | Proces za pripremu supstituisanih derivata pirimidina |
JP6471103B2 (ja) | 2013-03-06 | 2019-02-13 | ヤンセン ファーマシューティカ エヌ.ベー. | ヒスタミンh4受容体のベンゾイミダゾール−2−イルピリミジンモジュレータ |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2675390A (en) * | 1950-05-19 | 1954-04-13 | Edgar F Rosenblatt | Hydrogenation of cyclic-compounds |
GB904117A (en) * | 1960-01-21 | 1962-08-22 | Abbott Lab | Improvements in or relating to catalytic reduction of pyridine and pyridine salts |
US3252982A (en) * | 1963-10-16 | 1966-05-24 | Ciba Geigy Corp | Benzhydryl compounds |
BR6464291D0 (pt) * | 1963-11-26 | 1973-07-26 | Merrell Inc Richardson | Processo para preparar o novo composto quimico 1-1-di cloro-hexil-2-(2-piperidil)-etina |
DE2643473A1 (de) * | 1975-09-29 | 1977-04-14 | Btb Ind Chimica | Verfahren zur herstellung von 1,1-dicyclohexyl-2-(2'-piperidyl)- aethan |
-
1976
- 1976-04-14 US US05/677,036 patent/US4191828A/en not_active Expired - Lifetime
-
1977
- 1977-02-23 IE IE387/77A patent/IE44619B1/en not_active IP Right Cessation
- 1977-02-24 GB GB7759/77A patent/GB1513713A/en not_active Expired
- 1977-02-24 ZA ZA00771115A patent/ZA771115B/xx unknown
- 1977-02-25 IL IL51551A patent/IL51551A/xx unknown
- 1977-02-25 CA CA272,757A patent/CA1066288A/en not_active Expired
- 1977-03-03 AU AU22880/77A patent/AU506052B2/en not_active Expired
- 1977-03-10 DK DK105777A patent/DK156647C/da not_active IP Right Cessation
- 1977-03-16 NL NL7702823A patent/NL7702823A/xx active Search and Examination
- 1977-03-22 JP JP3051677A patent/JPS52125173A/ja active Granted
- 1977-03-23 AR AR266952A patent/AR211572A1/es active
- 1977-03-30 DE DE19772714081 patent/DE2714081A1/de active Granted
- 1977-04-01 PH PH19613A patent/PH11876A/en unknown
- 1977-04-04 ES ES457513A patent/ES457513A1/es not_active Expired
- 1977-04-08 BE BE176579A patent/BE853433A/xx not_active IP Right Cessation
- 1977-04-12 SE SE7704176A patent/SE436201B/xx not_active IP Right Cessation
- 1977-04-13 FR FR7711131A patent/FR2348199A1/fr active Granted
- 1977-04-13 NO NO771269A patent/NO149845C/no unknown
- 1977-04-13 CH CH459577A patent/CH629189A5/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IE44619L (en) | 1977-10-14 |
AU506052B2 (en) | 1979-12-13 |
IL51551A (en) | 1979-10-31 |
NO149845B (no) | 1984-03-26 |
DE2714081C2 (es) | 1987-02-05 |
AU2288077A (en) | 1978-09-07 |
DK156647C (da) | 1990-02-05 |
US4191828A (en) | 1980-03-04 |
IL51551A0 (en) | 1977-04-29 |
PH11876A (en) | 1978-08-11 |
BE853433A (fr) | 1977-08-01 |
IE44619B1 (en) | 1982-01-27 |
DK156647B (da) | 1989-09-18 |
FR2348199A1 (fr) | 1977-11-10 |
JPS52125173A (en) | 1977-10-20 |
FR2348199B1 (es) | 1980-09-05 |
NO771269L (no) | 1977-10-17 |
GB1513713A (en) | 1978-06-07 |
CA1066288A (en) | 1979-11-13 |
DK105777A (da) | 1977-10-15 |
SE436201B (sv) | 1984-11-19 |
AR211572A1 (es) | 1978-01-30 |
NL7702823A (nl) | 1977-10-18 |
DE2714081A1 (de) | 1977-11-03 |
ZA771115B (en) | 1978-01-25 |
CH629189A5 (de) | 1982-04-15 |
JPS6120547B2 (es) | 1986-05-22 |
SE7704176L (sv) | 1977-10-15 |
NO149845C (no) | 1984-07-04 |
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