ES447490A1 - Glutamine derivatives process for their preparation and pharmaceutical compositions containing them - Google Patents
Glutamine derivatives process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- ES447490A1 ES447490A1 ES447490A ES447490A ES447490A1 ES 447490 A1 ES447490 A1 ES 447490A1 ES 447490 A ES447490 A ES 447490A ES 447490 A ES447490 A ES 447490A ES 447490 A1 ES447490 A1 ES 447490A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- general formula
- mineral
- substituted
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Process for obtaining new N-acetyl glutamines, of general formula i: ** (see formula) ** Wherein a is a hexagonal cyclic radical, selected from the group consisting of cyclohexyl and phenyl radicals, B is a hexagonal cyclic radical selected from the group consisting of cyclohexyl, cyclohexenyl, cyclohexadionyl, phenyl and phenyl radicals substituted by one or more halogens, a trifluoromethyl radical, a trifluoromethoxy radical, a trifluoromethylthio radical, a lower alkoxy, a methylenedioxy, a (lower alkyl) thio, a lower alkenyloxy or a lower alkyl, R is hydrogen or a lower allocyl radical, and R1 is hydrogen, a monovalent cation derived from a therapeutically compatible mineral or organic base, a lower alkyl or an alkyl radical substituted by one or more hydroxyls, one or more aminated groups, characterized in that a substituted acetic acid of general formula ii is condensed: ** (see formula) ** Wherein the substituents a, b and r have the meaning given above, or one of their functional derivatives, with glutamine or one of its functional derivatives of general formula iii: ** (see formula) ** Wherein r-1 has the meanings given above, to form a compound of general formula i, which may, if necessary, be salified by addition of a mineral or organic base or by the addition of a mineral or organic acid. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1805975A GB1522212A (en) | 1975-04-30 | 1975-04-30 | Glutamine derivatives process for their preparation and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES447490A1 true ES447490A1 (en) | 1977-07-01 |
Family
ID=10105943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES447490A Expired ES447490A1 (en) | 1975-04-30 | 1976-04-29 | Glutamine derivatives process for their preparation and pharmaceutical compositions containing them |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS527940A (en) |
| AU (1) | AU500221B2 (en) |
| BE (1) | BE841302A (en) |
| CA (1) | CA1091249A (en) |
| CH (1) | CH608785A5 (en) |
| DE (1) | DE2618936C3 (en) |
| ES (1) | ES447490A1 (en) |
| FR (1) | FR2309221A1 (en) |
| GB (1) | GB1522212A (en) |
| NL (1) | NL7604502A (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4250192A (en) * | 1977-05-11 | 1981-02-10 | Ciba-Geigy Corporation | Novel substituted phenylacetic acid amide compounds |
| LU78106A1 (en) * | 1977-05-11 | 1979-05-23 | Ciba Geigy Ag | PROCESS FOR PREPARING NEW SUBSTITUTED PHENYL ACID AMIDE COMPOUNDS |
| US5646182A (en) * | 1992-06-15 | 1997-07-08 | Burzynski; Stanislaw R. | Methods for treating autoimmune diseases |
| ATE159713T1 (en) * | 1992-12-09 | 1997-11-15 | Kyowa Hakko Kogyo Kk | N-ACYLGLUTAMINE DERIVATIVES |
| WO1997003171A1 (en) * | 1995-07-12 | 1997-01-30 | Kyowa Hakko Kogyo Co., Ltd. | Detergent composition |
-
1975
- 1975-04-30 CH CH765473A patent/CH608785A5/en not_active IP Right Cessation
- 1975-04-30 GB GB1805975A patent/GB1522212A/en not_active Expired
-
1976
- 1976-04-22 FR FR7611812A patent/FR2309221A1/en active Granted
- 1976-04-26 CA CA251,068A patent/CA1091249A/en not_active Expired
- 1976-04-28 NL NL7604502A patent/NL7604502A/en not_active Application Discontinuation
- 1976-04-28 JP JP4931376A patent/JPS527940A/en active Pending
- 1976-04-29 DE DE19762618936 patent/DE2618936C3/en not_active Expired
- 1976-04-29 ES ES447490A patent/ES447490A1/en not_active Expired
- 1976-04-29 BE BE166593A patent/BE841302A/en unknown
- 1976-04-29 AU AU13470/76A patent/AU500221B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2618936B2 (en) | 1978-09-07 |
| JPS527940A (en) | 1977-01-21 |
| FR2309221A1 (en) | 1976-11-26 |
| NL7604502A (en) | 1976-11-02 |
| BE841302A (en) | 1976-10-29 |
| FR2309221B1 (en) | 1982-08-20 |
| GB1522212A (en) | 1978-08-23 |
| AU1347076A (en) | 1977-11-03 |
| DE2618936A1 (en) | 1976-11-04 |
| DE2618936C3 (en) | 1979-05-03 |
| CH608785A5 (en) | 1979-01-31 |
| CA1091249A (en) | 1980-12-09 |
| AU500221B2 (en) | 1979-05-17 |
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