ES439430A1 - Stilbene derivatives - Google Patents

Stilbene derivatives

Info

Publication number
ES439430A1
ES439430A1 ES439430A ES439430A ES439430A1 ES 439430 A1 ES439430 A1 ES 439430A1 ES 439430 A ES439430 A ES 439430A ES 439430 A ES439430 A ES 439430A ES 439430 A1 ES439430 A1 ES 439430A1
Authority
ES
Spain
Prior art keywords
defined above
stilbene derivatives
general formula
lower alcohol
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES439430A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of ES439430A1 publication Critical patent/ES439430A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/194—Radicals derived from thio- or thiono carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/794—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring
    • C07C49/796—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/42—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A procedure that prepares new stilbene derivatives represented by the general formula (I) ** (See formula) ** wherein R1 and R2 are independently hydrogen, lower alcohol, lower alkoxy, halogen, or haloalkoxy, and R3 is hydrogen or lower alcohol, which comprises hydrolyzing the compounds represented by the general formula (II) where R1 and R2 are as defined above and M is -HC (R3) CN, where R3 is as defined above, -CH2C (S) B, where B is amino, -HC (R3) C00A, where R3 is as defined above and A, is alcoholic, or -C (R3) (C00A) 2 where R3 and A are as defined above, in water, an organic solvent, or a mixture of the same, in the presence of acid or alkali, and then decarboxylate when M is -C (R3) (C00A) 2. (Machine-translation by Google Translate, not legally binding)
ES439430A 1974-07-16 1975-07-15 Stilbene derivatives Expired ES439430A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49081299A JPS5111748A (en) 1974-07-16 1974-07-16 Suchirubenjudotaino seizoho

Publications (1)

Publication Number Publication Date
ES439430A1 true ES439430A1 (en) 1977-02-01

Family

ID=13742501

Family Applications (1)

Application Number Title Priority Date Filing Date
ES439430A Expired ES439430A1 (en) 1974-07-16 1975-07-15 Stilbene derivatives

Country Status (12)

Country Link
JP (1) JPS5111748A (en)
AR (1) AR205387A1 (en)
AU (1) AU470771B2 (en)
CA (1) CA1053257A (en)
CH (1) CH610582A5 (en)
DE (1) DE2531456A1 (en)
ES (1) ES439430A1 (en)
FR (1) FR2278332A1 (en)
GB (1) GB1465661A (en)
NL (1) NL7507803A (en)
PH (1) PH11312A (en)
SE (1) SE409452B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2832213A1 (en) * 1978-07-21 1980-01-31 Bayer Ag STILEN DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS INSECTICIDES
DE2944428C2 (en) * 1979-11-03 1984-08-30 Trützschler GmbH & Co KG, 4050 Mönchengladbach Device for production control and sliver regulation of a card
FR2492815A1 (en) * 1980-10-23 1982-04-30 Sori Soc Rech Ind NEW CINNAMOYL-CINNAMIC ACID DERIVATIVE, PREPARATION METHOD AND THERAPEUTIC APPLICATION THEREOF
SE8400239D0 (en) * 1984-01-19 1984-01-19 Pharmacia Ab NEW ARYLETIC ACID DERIVATIVES
CH659814A5 (en) * 1984-03-27 1987-02-27 Ciba Geigy Ag STYLE DERIVATIVES.
TWI262185B (en) * 1999-10-01 2006-09-21 Eisai Co Ltd Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives
CA2393297C (en) * 1999-12-06 2010-10-05 Welichem Biotech Inc. Polyhydroxystilbenes as antipsoriatic agents and protein kinase inhibitors
US7321050B2 (en) 1999-12-06 2008-01-22 Welichem Biotech Inc. Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues
ITMI20012434A1 (en) * 2001-11-20 2003-05-20 Dompe Spa 2-ARYL-PROPIONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
AU2016263161B2 (en) 2015-05-21 2019-02-28 Dermavant Sciences GmbH Topical pharmaceutical compositions
US11617724B2 (en) 2015-05-21 2023-04-04 Dermavant Sciences GmbH Topical pharmaceutical compositions
CN111511357B (en) 2017-11-10 2024-04-09 德玛万科学有限责任公司 Process for preparing tazicar
US11497718B2 (en) 2018-11-13 2022-11-15 Dermavant Sciences GmbH Use of tapinarof for the treatment of atopic dermatitis

Also Published As

Publication number Publication date
SE409452B (en) 1979-08-20
CA1053257A (en) 1979-04-24
AR205387A1 (en) 1976-04-30
SE7508074L (en) 1976-01-19
AU8215275A (en) 1976-03-25
GB1465661A (en) 1977-02-23
PH11312A (en) 1977-11-02
DE2531456A1 (en) 1976-02-05
FR2278332B1 (en) 1980-05-16
CH610582A5 (en) 1979-04-30
JPS5111748A (en) 1976-01-30
FR2278332A1 (en) 1976-02-13
AU470771B2 (en) 1976-03-25
JPS5227B2 (en) 1977-01-05
NL7507803A (en) 1976-01-20

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