ES406726A1 - A procedure for preparing substituted benzoic acid dimetilsulfoxidos and dimetilsulfonas. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for preparing substituted benzoic acid dimetilsulfoxidos and dimetilsulfonas. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES406726A1 ES406726A1 ES406726A ES406726A ES406726A1 ES 406726 A1 ES406726 A1 ES 406726A1 ES 406726 A ES406726 A ES 406726A ES 406726 A ES406726 A ES 406726A ES 406726 A1 ES406726 A1 ES 406726A1
- Authority
- ES
- Spain
- Prior art keywords
- benzoic acid
- formula
- translation
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
A method of preparing dimethylsulfoxide and dimethylsufones of substituted benzoic acid of formula (IX) **(See formula)** where R1 is one or more alkoxy groups, preferably containing 1 to 4 carbon atoms (eg methoxy, ethoxy, n-propoxy, t-butoxy), R2 is an optional substituent, such as a halogen atom, especially chlorine, bromine or iodine, an alcohol group, preferably containing from 1 to 4 carbon atoms (eg, methyl, ethyl, propyl or butyl), an amido group or an amino group, and n is 1 or 2, which comprises making react a benzoic acid derivative of formula (VIII) **(See formula)** where R1 and R2 are as defined above and R is an alcohol group preferably having 1 to 4 carbon atoms, with a compound of formula (VII) CH3.SOn.CH3 (VII) where n is 1 or 2, in the presence of a base, strong enough to provide the appropriate carbanion in a suitable amount, for the reaction. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2517169 | 1969-05-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES406726A1 true ES406726A1 (en) | 1975-10-01 |
Family
ID=10223379
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES379700A Expired ES379700A1 (en) | 1969-05-16 | 1970-05-14 | A procedure for preparing beta-amino-alpha-bencilacrilic nitril derivatives. (Machine-translation by Google Translate, not legally binding) |
ES406725A Expired ES406725A1 (en) | 1969-05-16 | 1972-09-15 | A procedure for preparing a substitute 2,4-diamino-5-bencilpirimidine. (Machine-translation by Google Translate, not legally binding) |
ES406726A Expired ES406726A1 (en) | 1969-05-16 | 1972-09-15 | A procedure for preparing substituted benzoic acid dimetilsulfoxidos and dimetilsulfonas. (Machine-translation by Google Translate, not legally binding) |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES379700A Expired ES379700A1 (en) | 1969-05-16 | 1970-05-14 | A procedure for preparing beta-amino-alpha-bencilacrilic nitril derivatives. (Machine-translation by Google Translate, not legally binding) |
ES406725A Expired ES406725A1 (en) | 1969-05-16 | 1972-09-15 | A procedure for preparing a substitute 2,4-diamino-5-bencilpirimidine. (Machine-translation by Google Translate, not legally binding) |
Country Status (14)
Country | Link |
---|---|
JP (1) | JPS505184B1 (en) |
AT (1) | AT308082B (en) |
BR (1) | BR6915082D0 (en) |
CA (1) | CA994812A (en) |
CH (1) | CH544071A (en) |
DE (1) | DE2023977C2 (en) |
ES (3) | ES379700A1 (en) |
FI (1) | FI56375C (en) |
FR (1) | FR2070070A1 (en) |
IL (1) | IL34433A (en) |
IT (1) | IT1021507B (en) |
NL (2) | NL173395C (en) |
PL (1) | PL92440B1 (en) |
SE (2) | SE400777B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1469521A (en) * | 1973-01-05 | 1977-04-06 | Wellcome Found | Antimicrobial preparations |
US4687861A (en) * | 1984-11-28 | 1987-08-18 | Ciba-Geigy Corporation | Microbicidal compositions |
PT1725540E (en) * | 2004-03-05 | 2012-11-29 | Hoffmann La Roche | Diaminopyrimidines as p2x3 and p2x2/3 antagonists |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3049544A (en) * | 1962-08-14 | Method for the preparation of | ||
DE1103931B (en) | 1957-02-21 | 1961-04-06 | Wellcome Found | Process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives |
DE1303727B (en) | 1959-09-03 | 1976-02-05 | Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London | Alpha-arylidene-substituted propioni-iriles |
NL122146C (en) * | 1960-09-02 | |||
DE1620729A1 (en) | 1965-07-08 | 1970-08-20 | Wellcome Found | Process for the preparation of substituted benzylpyrimidines |
GB1261455A (en) | 1969-03-06 | 1972-01-26 | Burroughs Wellcome Co | Improvements in or relating to substituted acrylonitriles |
-
1969
- 1969-12-12 BR BR215082/69A patent/BR6915082D0/en unknown
-
1970
- 1970-03-05 PL PL1970177150A patent/PL92440B1/en unknown
- 1970-03-06 AT AT100472A patent/AT308082B/en active
- 1970-05-01 IL IL34433A patent/IL34433A/en unknown
- 1970-05-13 FI FI1338/70A patent/FI56375C/en active
- 1970-05-14 ES ES379700A patent/ES379700A1/en not_active Expired
- 1970-05-15 SE SE7006713A patent/SE400777B/en unknown
- 1970-05-15 JP JP45041540A patent/JPS505184B1/ja active Pending
- 1970-05-15 IT IT50715/70A patent/IT1021507B/en active
- 1970-05-15 CH CH732370A patent/CH544071A/en not_active IP Right Cessation
- 1970-05-15 DE DE2023977A patent/DE2023977C2/en not_active Expired
- 1970-05-15 NL NLAANVRAGE7007108,A patent/NL173395C/en not_active IP Right Cessation
- 1970-05-15 FR FR7017799A patent/FR2070070A1/en active Granted
- 1970-05-19 CA CA083,401A patent/CA994812A/en not_active Expired
-
1972
- 1972-09-15 ES ES406725A patent/ES406725A1/en not_active Expired
- 1972-09-15 ES ES406726A patent/ES406726A1/en not_active Expired
-
1973
- 1973-06-07 SE SE7308030A patent/SE398878B/en unknown
-
1980
- 1980-08-25 NL NL8004796A patent/NL8004796A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL34433A (en) | 1971-10-20 |
IT1021507B (en) | 1978-02-20 |
DE2023977C2 (en) | 1984-03-15 |
CH544071A (en) | 1973-11-15 |
DE2023977A1 (en) | 1971-02-18 |
ES406725A1 (en) | 1975-10-01 |
SE400777B (en) | 1978-04-10 |
ES379700A1 (en) | 1973-01-16 |
NL173395C (en) | 1984-01-16 |
FR2070070A1 (en) | 1971-09-10 |
NL7007108A (en) | 1970-11-18 |
FR2070070B1 (en) | 1974-10-11 |
NL173395B (en) | 1983-08-16 |
FI56375C (en) | 1980-01-10 |
PL92440B1 (en) | 1977-04-30 |
FI56375B (en) | 1979-09-28 |
NL8004796A (en) | 1980-11-28 |
SE398878B (en) | 1978-01-23 |
JPS505184B1 (en) | 1975-02-28 |
IL34433A0 (en) | 1970-07-19 |
AT308082B (en) | 1973-06-25 |
CA994812A (en) | 1976-08-10 |
BR6915082D0 (en) | 1973-03-08 |
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