ES401541A1 - Un procedimiento de preparacion de quinoleinas sustituidas. - Google Patents
Un procedimiento de preparacion de quinoleinas sustituidas.Info
- Publication number
- ES401541A1 ES401541A1 ES401541A ES401541A ES401541A1 ES 401541 A1 ES401541 A1 ES 401541A1 ES 401541 A ES401541 A ES 401541A ES 401541 A ES401541 A ES 401541A ES 401541 A1 ES401541 A1 ES 401541A1
- Authority
- ES
- Spain
- Prior art keywords
- alcohol
- formula
- radical
- see formula
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000005011 4-aminoquinolines Chemical class 0.000 title 1
- -1 alcohol radical Chemical class 0.000 abstract 10
- 125000004432 carbon atom Chemical group C* 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- 229910052801 chlorine Inorganic materials 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- 125000003158 alcohol group Chemical group 0.000 abstract 2
- 239000002585 base Substances 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 2
- 150000003254 radicals Chemical class 0.000 abstract 2
- WNXJIVFYUVYPPR-UHFFFAOYSA-N 1,3-dioxolane Chemical compound C1COCO1 WNXJIVFYUVYPPR-UHFFFAOYSA-N 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 229940111121 antirheumatic drug quinolines Drugs 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 150000002148 esters Chemical group 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 238000005809 transesterification reaction Methods 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7112460A FR2132545B1 (es) | 1971-04-08 | 1971-04-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES401541A1 true ES401541A1 (es) | 1975-02-16 |
Family
ID=9074974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES401541A Expired ES401541A1 (es) | 1971-04-08 | 1972-04-07 | Un procedimiento de preparacion de quinoleinas sustituidas. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3808216A (es) |
| JP (1) | JPS558985B1 (es) |
| AT (1) | AT317216B (es) |
| BE (1) | BE781741A (es) |
| CA (1) | CA956633A (es) |
| CH (2) | CH552620A (es) |
| DD (1) | DD97211A5 (es) |
| DK (1) | DK136038B (es) |
| ES (1) | ES401541A1 (es) |
| FR (1) | FR2132545B1 (es) |
| GB (1) | GB1387595A (es) |
| HU (1) | HU167367B (es) |
| IE (1) | IE36270B1 (es) |
| IL (1) | IL39081A (es) |
| NL (1) | NL173957C (es) |
| SE (1) | SE372944B (es) |
| ZA (1) | ZA722298B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2341313A1 (fr) * | 1976-02-23 | 1977-09-16 | Roussel Uclaf | Nouvelles quinoleines substituees, leur procede de preparation et leur application comme medicament |
| FR2503163A1 (fr) * | 1981-04-03 | 1982-10-08 | Roussel Uclaf | Nouveaux derives de l'acide 3-/4-quinoleinyl-amino/2-thiophene carboxylique, leur procede de preparation et leur application comme medicament |
| AU2011272857A1 (en) * | 2010-06-30 | 2013-01-10 | Amgen Inc. | Quinolines as P13K inhibitors |
-
1971
- 1971-04-08 FR FR7112460A patent/FR2132545B1/fr not_active Expired
-
1972
- 1972-03-26 IL IL39081A patent/IL39081A/xx unknown
- 1972-04-05 DK DK161972AA patent/DK136038B/da not_active IP Right Cessation
- 1972-04-05 US US00241405A patent/US3808216A/en not_active Expired - Lifetime
- 1972-04-05 ZA ZA722298A patent/ZA722298B/xx unknown
- 1972-04-06 NL NLAANVRAGE7204621,A patent/NL173957C/xx not_active IP Right Cessation
- 1972-04-06 BE BE781741A patent/BE781741A/xx not_active IP Right Cessation
- 1972-04-06 CH CH837473A patent/CH552620A/fr not_active IP Right Cessation
- 1972-04-06 CH CH506072A patent/CH552619A/fr not_active IP Right Cessation
- 1972-04-07 SE SE7204543A patent/SE372944B/xx unknown
- 1972-04-07 HU HURO654A patent/HU167367B/hu unknown
- 1972-04-07 CA CA139,249*7A patent/CA956633A/en not_active Expired
- 1972-04-07 JP JP3451772A patent/JPS558985B1/ja active Pending
- 1972-04-07 DD DD162138A patent/DD97211A5/xx unknown
- 1972-04-07 ES ES401541A patent/ES401541A1/es not_active Expired
- 1972-04-10 AT AT308672A patent/AT317216B/de not_active IP Right Cessation
- 1972-04-10 IE IE462/72A patent/IE36270B1/xx unknown
- 1972-04-10 GB GB1648972A patent/GB1387595A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL7204621A (es) | 1972-10-10 |
| GB1387595A (en) | 1975-03-19 |
| IE36270B1 (en) | 1976-09-29 |
| NL173957C (nl) | 1984-04-02 |
| NL173957B (nl) | 1983-11-01 |
| BE781741A (fr) | 1972-10-06 |
| CH552620A (fr) | 1974-08-15 |
| IE36270L (en) | 1972-10-08 |
| AT317216B (de) | 1974-08-26 |
| DK136038B (da) | 1977-08-01 |
| SU440835A3 (es) | 1974-08-25 |
| IL39081A (en) | 1975-11-25 |
| SE372944B (es) | 1975-01-20 |
| IL39081A0 (en) | 1972-05-30 |
| US3808216A (en) | 1974-04-30 |
| CA956633A (en) | 1974-10-22 |
| ZA722298B (en) | 1973-06-27 |
| HU167367B (es) | 1975-09-27 |
| CH552619A (fr) | 1974-08-15 |
| DE2216212B2 (de) | 1975-11-27 |
| FR2132545A1 (es) | 1972-11-24 |
| FR2132545B1 (es) | 1974-08-02 |
| DD97211A5 (es) | 1973-04-20 |
| DK136038C (es) | 1978-01-02 |
| DE2216212A1 (de) | 1972-10-19 |
| JPS558985B1 (es) | 1980-03-07 |
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