ES380579A1 - Un procedimiento para la preparacion de un n-(5(6)-acil-2- bencimidazolil) carbamato de alquilo. - Google Patents
Un procedimiento para la preparacion de un n-(5(6)-acil-2- bencimidazolil) carbamato de alquilo.Info
- Publication number
- ES380579A1 ES380579A1 ES380579A ES380579A ES380579A1 ES 380579 A1 ES380579 A1 ES 380579A1 ES 380579 A ES380579 A ES 380579A ES 380579 A ES380579 A ES 380579A ES 380579 A1 ES380579 A1 ES 380579A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- phenyl
- compound
- group
- member selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BHFLSZOGGDDWQM-UHFFFAOYSA-N 1h-benzimidazole;carbamic acid Chemical class NC(O)=O.C1=CC=C2NC=NC2=C1 BHFLSZOGGDDWQM-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83524669A | 1969-06-20 | 1969-06-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES380579A1 true ES380579A1 (es) | 1973-04-01 |
Family
ID=25269027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES380579A Expired ES380579A1 (es) | 1969-06-20 | 1970-06-09 | Un procedimiento para la preparacion de un n-(5(6)-acil-2- bencimidazolil) carbamato de alquilo. |
Country Status (20)
Country | Link |
---|---|
US (1) | US3657267A (es) |
JP (1) | JPS501272B1 (es) |
AT (2) | AT307798B (es) |
BE (1) | BE752089A (es) |
CH (1) | CH520684A (es) |
CS (1) | CS201522B2 (es) |
DK (2) | DK134602B (es) |
ES (1) | ES380579A1 (es) |
FI (1) | FI52719C (es) |
FR (1) | FR2052988B1 (es) |
GB (1) | GB1307306A (es) |
HK (1) | HK77976A (es) |
IL (1) | IL34746A (es) |
IT (1) | IT1035027B (es) |
MY (1) | MY7300477A (es) |
NL (1) | NL147139B (es) |
PL (1) | PL72724B1 (es) |
SE (1) | SE366045B (es) |
YU (1) | YU34195B (es) |
ZA (1) | ZA704191B (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2201208A1 (de) * | 1972-01-12 | 1973-08-02 | Basf Ag | Verfahren zur herstellung von aromatischen ketonen |
US3929821A (en) * | 1972-12-29 | 1975-12-30 | Syntex Inc | 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives |
US4258198A (en) * | 1973-05-29 | 1981-03-24 | Smithkline Corporation | 5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles |
US3969526A (en) * | 1973-05-29 | 1976-07-13 | Smithkline Corporation | Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles |
DE2443297A1 (de) * | 1974-09-10 | 1976-03-18 | Hoechst Ag | Anthelminthisch wirksame basisch substituierte 2-carbalkoxy-amino-benzimidazolyl-5(6)-phenylaether und -ketone sowie verfahren zu ihrer herstellung |
US4026936A (en) * | 1975-08-07 | 1977-05-31 | Hoffmann-La Roche Inc. | Anthelmintic pyridine and thiazole substituted benzimidazole carbamates |
US4031234A (en) * | 1975-08-18 | 1977-06-21 | Syntex (U.S.A.) Inc. | 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US4032536A (en) * | 1976-07-22 | 1977-06-28 | Janssen Pharmaceutica N.V. | (1h-benzimidazol-2-yl)carbamates |
IT1076022B (it) * | 1977-04-20 | 1985-04-22 | Montedison Spa | Benzimidazolcarbammati antielmintici |
JPS5535611A (en) * | 1978-08-31 | 1980-03-12 | Matsushita Electric Works Ltd | Instrument with mouth washing instrument |
US4299837A (en) | 1979-12-05 | 1981-11-10 | Montedison S.P.A. | Anthelmintic benzimidazole-carbamates |
US4435418A (en) | 1982-12-13 | 1984-03-06 | Smithkline Beckman Corporation | 5-Phenylethenylbenzimidazoles |
US4438135A (en) | 1983-01-07 | 1984-03-20 | Smithkline Beckman Corporation | 1-(3,4-Bis-(3-(lower alkoxycarbonyl)-2-thioureido)-phenyl-1-phenylthylenes |
US5256681A (en) * | 1989-03-15 | 1993-10-26 | Janssen Pharmaceutica N.V. | [5(6)-(benzisoxa-,benzisothia-or indazol-3-yl)-1H-benzimidazol-2-yl]carbamates |
WO1990010630A1 (en) * | 1989-03-15 | 1990-09-20 | Janssen Pharmaceutica N.V. | [5(6)-(benzisoxa-, benzisothia- or indazol-3-yl)-1h-benzimidazol-2-yl] carbamates |
NZ232785A (en) * | 1989-03-15 | 1991-03-26 | Janssen Pharmaceutica Nv | 5-(1,2 benzisoxazol-, benzimidazol and benzisothiazol-3- yl)-1h-benzimadazol-2-yl carbamic acid ester derivatives preparatory processes, intermediates and anthelmintic compositions |
US5278181A (en) * | 1992-05-12 | 1994-01-11 | Board Of Regents Acting On Behalf Of The University Of Michigan | Soluble alkyl[5-[amino (phenyl)methyl]-1H-benzimidazol-2-yl] carbamate anthelmintics |
PT1913009E (pt) * | 2005-07-28 | 2010-06-25 | Intervet Int Bv | Novos (tio)carbamatos de benzimidazole com actividade antiparasitária e sua síntese |
JP5406022B2 (ja) * | 2006-06-12 | 2014-02-05 | スミス アンド ネフュー インコーポレーテッド | 脛骨切除システム、方法、及び装置 |
MX2008015764A (es) | 2006-06-14 | 2009-01-07 | Intervet Int Bv | Suspension que comprende carbamato de bencimidazol y polisorbato. |
BR112014018149B1 (pt) | 2012-01-27 | 2020-09-29 | Siegfried Rhein S.A. De C.V | Composição farmacêutica de nitazoxanida |
MX340272B (es) | 2012-09-27 | 2016-06-30 | Rhein Siegfried Sa De Cv | Composicion sinergica de nitazoxanida y mebendazol, procesos para prepararla y el uso de dicha composicion para el tratamiento de la parasitosis humana. |
CN108884054B (zh) | 2015-11-30 | 2022-08-02 | 儿童医学中心公司 | 用于治疗增殖性疾病的化合物 |
WO2018235103A1 (en) | 2017-06-22 | 2018-12-27 | Cipla Limited | METHOD OF TREATING CANCER |
CN109467512B (zh) * | 2018-12-18 | 2021-06-08 | 苏州开元民生科技股份有限公司 | 一种3,4-二氨基-二苯甲酮的合成方法 |
CN113979949A (zh) * | 2021-12-17 | 2022-01-28 | 山东国邦药业有限公司 | 一种氟苯咪唑的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1111957A (en) * | 1966-05-20 | 1968-05-01 | Smith Kline French Lab | Improvements in or relating to anthelmintic compositions |
-
1969
- 1969-06-20 US US835246A patent/US3657267A/en not_active Expired - Lifetime
-
1970
- 1970-05-29 GB GB2604470A patent/GB1307306A/en not_active Expired
- 1970-05-29 CH CH809370A patent/CH520684A/fr not_active IP Right Cessation
- 1970-06-08 FR FR707021022A patent/FR2052988B1/fr not_active Expired
- 1970-06-09 ES ES380579A patent/ES380579A1/es not_active Expired
- 1970-06-16 PL PL1970141321A patent/PL72724B1/pl unknown
- 1970-06-17 BE BE752089D patent/BE752089A/xx not_active IP Right Cessation
- 1970-06-17 SE SE08385/70A patent/SE366045B/xx unknown
- 1970-06-18 FI FI701720A patent/FI52719C/fi active
- 1970-06-18 IL IL34746A patent/IL34746A/xx unknown
- 1970-06-18 IT IT51551/70A patent/IT1035027B/it active
- 1970-06-18 AT AT549770A patent/AT307798B/de not_active IP Right Cessation
- 1970-06-18 YU YU1544/70A patent/YU34195B/xx unknown
- 1970-06-18 AT AT825571A patent/AT302358B/de not_active IP Right Cessation
- 1970-06-19 ZA ZA704191A patent/ZA704191B/xx unknown
- 1970-06-19 JP JP45053435A patent/JPS501272B1/ja active Pending
- 1970-06-19 CS CS704330A patent/CS201522B2/cs unknown
- 1970-06-19 NL NL707009024A patent/NL147139B/xx not_active IP Right Cessation
- 1970-06-22 DK DK321770AA patent/DK134602B/da not_active IP Right Cessation
-
1973
- 1973-12-30 MY MY477/73A patent/MY7300477A/xx unknown
-
1975
- 1975-12-19 DK DK580275A patent/DK580275A/da unknown
-
1976
- 1976-12-09 HK HK779/76*UA patent/HK77976A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
FI52719C (fi) | 1977-11-10 |
CS201522B2 (en) | 1980-11-28 |
HK77976A (en) | 1976-12-17 |
FR2052988A1 (es) | 1971-04-16 |
MY7300477A (en) | 1973-12-31 |
YU34195B (en) | 1979-02-28 |
ZA704191B (en) | 1972-02-23 |
DK134602B (da) | 1976-12-06 |
YU154470A (en) | 1978-09-18 |
IL34746A (en) | 1973-01-30 |
PL72724B1 (es) | 1974-08-30 |
DK580275A (da) | 1975-12-19 |
SE366045B (es) | 1974-04-08 |
GB1307306A (en) | 1973-02-21 |
IT1035027B (it) | 1979-10-20 |
US3657267A (en) | 1972-04-18 |
JPS501272B1 (es) | 1975-01-16 |
IL34746A0 (en) | 1970-08-19 |
FR2052988B1 (es) | 1973-08-10 |
DK134602C (es) | 1977-06-27 |
NL147139B (nl) | 1975-09-15 |
DE2029637B2 (de) | 1976-09-23 |
DE2029637A1 (de) | 1971-02-18 |
CH520684A (fr) | 1972-03-31 |
AT307798B (de) | 1973-06-12 |
BE752089A (fr) | 1970-12-17 |
AT302358B (de) | 1972-10-10 |
NL7009024A (es) | 1970-12-22 |
FI52719B (es) | 1977-08-01 |
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