ES368730A1 - Benzodioxole compounds - Google Patents

Abstract

Pharmaceutical compositions, which may be administered orally, parenterally or by pellet implantation contain as active ingredients novel benzodioxole derivatives of the formula wherein R1 is NH 2 , alkylamino, dialkylamino, morpholino, piperidino, pyrrolidino or dialkylaminoalkylamino, or OR9 wherein R9 is H, C 1-4 alkyl or a pharmaceutically acceptable inorganic or organic cation, R2 and R3 are the same or different and each is H or C 1-4 alkyl, R4, R5 and R6 are the same or different and each one is H, F, Cl, CF 3 , NO 2 or OH, C 1-4 alkyl, or C 1-4 alkoxy, R7 is H or C 1-4 alkyl, R8 is alkyl, alkenyl or cycloalkyl containing up to eight carbon atoms, optionally substituted with Cl, OH or C 1-4 alkoxy or an aryl group optionally substituted with not more than three equal or different substituents selected from Cl, F, CF 3 , NO 2 , OH, C 1-4 alkyl and C 1-4 alkoxy or R8 forms together with R7 and the carbon atom to which they are attached a cycloaliphatic ring containing up to seven carbon atoms, and pharmaceutically acceptable carriers. The above compositions, which may also contain other active ingredients such as analgesics, tranquillizers, steroids or hormones, have anti-inflammatory and/or analgesic and/or anti-pyretic activity.