ES2606173T3 - Composición farmacéutica para el tratamiento y/o la prevención del cáncer - Google Patents

Composición farmacéutica para el tratamiento y/o la prevención del cáncer Download PDF

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Publication number
ES2606173T3
ES2606173T3 ES11739881.8T ES11739881T ES2606173T3 ES 2606173 T3 ES2606173 T3 ES 2606173T3 ES 11739881 T ES11739881 T ES 11739881T ES 2606173 T3 ES2606173 T3 ES 2606173T3
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fragment
lys
antibody
acid sequence
amino acid
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ES11739881.8T
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English (en)
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Shinichi Kobayashi
Fumiyoshi Okano
Takanori Saito
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Toray Industries Inc
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Toray Industries Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Un anticuerpo o un fragmento del mismo, en donde el anticuerpo o el fragmento tienen una actividad citotóxica contra una célula cancerosa que expresa una proteína CAPRIN-1 y: (a) se unen a un polipéptido que consiste en la secuencia de aminoácidos representada por la SEQ ID NO: 37; o (b) reconocen un fragmento que consiste en entre 7 y 12 aminoácidos de la secuencia de aminoácidos de la SEQ ID NO: 37, con la condición de que el anticuerpo o el fragmento del mismo no se unan a un polipéptido que consiste en la secuencia de aminoácidos Arg-Asn-Leu-Glu-Lys-Lys-Lys-Gly-Lys-Leu-Asp-Asp-Tyr-Gln o a un fragmento que consiste en entre 7 y 12 aminoácidos de la misma.

Description

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Claims (1)

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ES11739881.8T 2010-02-04 2011-02-04 Composición farmacéutica para el tratamiento y/o la prevención del cáncer Active ES2606173T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2010023453 2010-02-04
JP2010023453 2010-02-04
JP2010183161 2010-08-18
JP2010183161 2010-08-18
PCT/JP2011/052412 WO2011096533A1 (ja) 2010-02-04 2011-02-04 癌の治療及び／又は予防用医薬組成物

Publications (1)

Publication Number Publication Date
ES2606173T3 true ES2606173T3 (es) 2017-03-23

Family

ID=44355527

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11739881.8T Active ES2606173T3 (es) 2010-02-04 2011-02-04 Composición farmacéutica para el tratamiento y/o la prevención del cáncer

Country Status (16)

Country Link
US (1) US8937160B2 (es)
EP (1) EP2532366B1 (es)
JP (1) JP5742713B2 (es)
KR (1) KR101801667B1 (es)
CN (1) CN102821789B (es)
AU (1) AU2011211698B2 (es)
BR (1) BR112012018951C8 (es)
CA (1) CA2788716C (es)
DK (1) DK2532366T3 (es)
ES (1) ES2606173T3 (es)
HU (1) HUE030742T2 (es)
MX (1) MX342291B (es)
PL (1) PL2532366T3 (es)
PT (1) PT2532366T (es)
RU (1) RU2597971C2 (es)
WO (1) WO2011096533A1 (es)

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HUE027332T2 (en) 2008-08-05 2016-09-28 Toray Industries Cancer Detection Method
PT2322221E (pt) 2008-08-05 2014-09-19 Toray Industries Composição farmacêutica para tratamento e prevenção de cancro
DK2532366T3 (da) 2010-02-04 2017-01-02 Toray Industries Farmaceutisk sammensætning til behandling og/eller forebyggelse af cancer
PT2532743E (pt) 2010-02-04 2015-08-04 Toray Industries Composição farmacêutica para o tratamento e/ou a prevenção de cancro
ES2583777T3 (es) 2010-02-04 2016-09-22 Toray Industries, Inc. Composición farmacéutica que comprende anticuerpos anti CAPRIN-1 para el tratamiento y/o la prevención del cáncer
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PT3351630T (pt) 2011-08-04 2019-12-30 Toray Industries Composição farmacêutica compreendendo anticorpos anti caprin-1 para tratar e/ou prevenir o cancro
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WO2019189780A1 (ja) 2018-03-30 2019-10-03 東レ株式会社 癌の治療及び／又は予防用医薬組成物
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EP4119157A4 (en) 2020-03-12 2024-03-27 Toray Industries MEDICINE FOR THE TREATMENT AND/OR PREVENTION OF CANCER
WO2021182572A1 (ja) 2020-03-12 2021-09-16 東レ株式会社 癌の治療及び／又は予防のための医薬品
BR112022018161A2 (pt) 2020-03-12 2022-10-25 Toray Industries Medicamento para o tratamento e/ou prevenção do câncer, agentes que aumentam a eficácia de um fármaco e método para o tratamento e/ou prevenção do câncer
WO2021182573A1 (ja) 2020-03-12 2021-09-16 東レ株式会社 癌の治療及び／又は予防のための医薬品
KR20220152309A (ko) 2020-03-12 2022-11-15 도레이 카부시키가이샤 암의 치료 및/또는 예방을 위한 의약품
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Also Published As

Publication number Publication date
EP2532366A4 (en) 2013-12-04
MX2012009000A (es) 2012-08-31
JP5742713B2 (ja) 2015-07-01
BR112012018951B1 (pt) 2020-05-12
EP2532366B1 (en) 2016-09-07
US8937160B2 (en) 2015-01-20
MX342291B (es) 2016-09-23
CN102821789A (zh) 2012-12-12
AU2011211698A1 (en) 2012-08-23
KR101801667B1 (ko) 2017-11-27
CN102821789B (zh) 2016-03-02
AU2011211698B2 (en) 2015-07-16
HUE030742T2 (en) 2017-06-28
RU2597971C2 (ru) 2016-09-20
BR112012018951A2 (pt) 2017-06-27
KR20130033347A (ko) 2013-04-03
EP2532366A1 (en) 2012-12-12
CA2788716C (en) 2019-06-18
US20130045210A1 (en) 2013-02-21
CA2788716A1 (en) 2011-08-11
BR112012018951C8 (pt) 2020-06-23
BR112012018951B8 (pt) 2020-06-09
WO2011096533A1 (ja) 2011-08-11
DK2532366T3 (da) 2017-01-02
PT2532366T (pt) 2016-12-20
BR112012018951A8 (pt) 2020-03-31
RU2012137504A (ru) 2014-03-10
JPWO2011096533A1 (ja) 2013-06-13
PL2532366T3 (pl) 2017-02-28

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