ES2519690T3 - Método de tratamiento de envenenamiento por organosfósforo - Google Patents

Método de tratamiento de envenenamiento por organosfósforo Download PDF

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Publication number
ES2519690T3
ES2519690T3 ES05812994.1T ES05812994T ES2519690T3 ES 2519690 T3 ES2519690 T3 ES 2519690T3 ES 05812994 T ES05812994 T ES 05812994T ES 2519690 T3 ES2519690 T3 ES 2519690T3
Authority
ES
Spain
Prior art keywords
poisoning
treatment
organosphorus
galantamine
exposure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES05812994.1T
Other languages
English (en)
Inventor
Edson X. Albuquerque
Michael Adler
Edna F. R. Pereira
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Maryland at Baltimore
US Government
US Department of Army
Original Assignee
University of Maryland at Baltimore
US Government
US Department of Army
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Maryland at Baltimore, US Government, US Department of Army filed Critical University of Maryland at Baltimore
Application granted granted Critical
Publication of ES2519690T3 publication Critical patent/ES2519690T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Galantamina y agente antimuscarinico para su uso en la prevencion o el tratamiento de envenenamiento por organofósforo (OP), que comprende administrar una cantidad de galantamina de inhibición del envenenamiento por OP a un mamifero despues de la exposición a un OP y administrar ademas una cantidad eficaz de un agente antimuscarinico despues de la exposición a un OP y antes de o de manera simultanea a la galantamina.

Description

imagen1
imagen2
imagen3

Claims (1)

  1. imagen1
ES05812994.1T 2004-09-24 2005-09-23 Método de tratamiento de envenenamiento por organosfósforo Active ES2519690T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61312104P 2004-09-24 2004-09-24
US613121P 2004-09-24
PCT/US2005/033789 WO2006036686A2 (en) 2004-09-24 2005-09-23 Method of treating organophosphorous poisoning

Publications (1)

Publication Number Publication Date
ES2519690T3 true ES2519690T3 (es) 2014-11-07

Family

ID=36119406

Family Applications (2)

Application Number Title Priority Date Filing Date
ES05812994.1T Active ES2519690T3 (es) 2004-09-24 2005-09-23 Método de tratamiento de envenenamiento por organosfósforo
ES14002959.6T Active ES2662868T3 (es) 2004-09-24 2005-09-23 Procedimiento para el tratamiento de una intoxicación por una sustancia organofosforada

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES14002959.6T Active ES2662868T3 (es) 2004-09-24 2005-09-23 Procedimiento para el tratamiento de una intoxicación por una sustancia organofosforada

Country Status (10)

Country Link
US (2) US7888346B2 (es)
EP (2) EP1791904B1 (es)
JP (2) JP5710092B2 (es)
CN (1) CN101044200A (es)
AU (1) AU2005289808B2 (es)
CA (1) CA2583439C (es)
ES (2) ES2519690T3 (es)
IL (2) IL182048A0 (es)
PL (2) PL1791904T3 (es)
WO (1) WO2006036686A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9132135B2 (en) * 2004-09-24 2015-09-15 University Of Maryland, Baltimore Method of treating organophosphorous poisoning
WO2008022365A2 (de) * 2006-08-24 2008-02-28 Sanochemia Ltd. Mittel zum beeinflussen der wirkungen von organophosphorverbindungen und verwendung von galanthamin, dessen derivaten und analoga zum herstellen solcher mittel
US20140120157A1 (en) 2012-09-19 2014-05-01 Georgetown University Targeted liposomes
EP2711000B1 (en) * 2012-09-19 2019-04-03 Georgetown University Targeted Liposomes
CN103041368B (zh) * 2013-01-18 2014-04-02 新乡医学院 藻蓝蛋白在制备防治有机磷农药所致胚胎毒性的药物中的应用

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RU2057531C1 (ru) 1986-07-01 1996-04-10 Всероссийский научный центр по безопасности биологически активных веществ Средство для стимуляции обучения и памяти
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
US5480651A (en) 1992-03-16 1996-01-02 Regents Of The University Of California Composition and method for treating nicotine craving in smoking cessation
DE4342173A1 (de) 1993-12-10 1995-06-14 Lohmann Therapie Syst Lts Pharmazeutische Formulierung zur Prophylaxe bzw. Vorbehandlung einer Vergiftung durch phosphororganische Cholinesterasehemmer
DE4342174C1 (de) * 1993-12-10 1995-05-11 Lohmann Therapie Syst Lts Transdermales therapeutisches System sowie ein Verfahren zur Herstellung eines transdermalen therapeutischen Systems zur kombinierten transdermalen Anwendung von Physostigmin und Scopolamin für die Prophylaxe und zur Vorbehandlung einer Vergiftung durch hochtoxische phosphororganische Nervengifte, insbesondere Soman und seine Verwendung
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Also Published As

Publication number Publication date
US20080070900A1 (en) 2008-03-20
WO2006036686A2 (en) 2006-04-06
EP1791904B1 (en) 2014-08-27
AU2005289808A2 (en) 2008-07-31
JP5710092B2 (ja) 2015-04-30
US8703762B2 (en) 2014-04-22
CA2583439A1 (en) 2006-04-06
PL1791904T3 (pl) 2015-02-27
EP1791904A2 (en) 2007-06-06
WO2006036686A3 (en) 2007-02-22
US20110144093A1 (en) 2011-06-16
JP2013173773A (ja) 2013-09-05
AU2005289808B2 (en) 2011-11-03
ES2662868T3 (es) 2018-04-10
EP2813225A1 (en) 2014-12-17
EP2813225B1 (en) 2017-12-13
IL182048A0 (en) 2007-07-24
IL218241A0 (en) 2012-04-30
PL2813225T3 (pl) 2018-11-30
CA2583439C (en) 2016-05-10
AU2005289808A1 (en) 2006-04-06
EP1791904A4 (en) 2009-01-21
JP2008514609A (ja) 2008-05-08
CN101044200A (zh) 2007-09-26
US7888346B2 (en) 2011-02-15
IL218241A (en) 2016-03-31

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