ES2512141T3 - Análogo peptídico de oxintomodulina - Google Patents

Análogo peptídico de oxintomodulina Download PDF

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Publication number
ES2512141T3
ES2512141T3 ES10799178.8T ES10799178T ES2512141T3 ES 2512141 T3 ES2512141 T3 ES 2512141T3 ES 10799178 T ES10799178 T ES 10799178T ES 2512141 T3 ES2512141 T3 ES 2512141T3
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ES
Spain
Prior art keywords
peptide analog
cys
oxintomodulin peptide
oxintomodulin
peg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10799178.8T
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English (en)
Inventor
Jorge Alsina-Fernandez
Wayne David Kohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
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Eli Lilly and Co
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43568014&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2512141(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
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Publication of ES2512141T3 publication Critical patent/ES2512141T3/es
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Un análogo peptídico de oxintomodulina que comprende la secuencia de aminoácidos:**Fórmula** en la que Xaa38 es Cys, Cys-PEG, o está ausente; Xaa39 es Cys, Cys-PEG, o está ausente; y en el que el aminoácido C-terminal está amidado opcionalmente.

Description

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Claims (1)

  1. imagen1
ES10799178.8T 2009-12-22 2010-12-15 Análogo peptídico de oxintomodulina Active ES2512141T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US28888409P 2009-12-22 2009-12-22
US288884P 2009-12-22
US35256910P 2010-06-08 2010-06-08
US352569P 2010-06-08
PCT/US2010/060380 WO2011087671A1 (en) 2009-12-22 2010-12-15 Oxyntomodulin peptide analogue

Publications (1)

Publication Number Publication Date
ES2512141T3 true ES2512141T3 (es) 2014-10-23

Family

ID=43568014

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10799178.8T Active ES2512141T3 (es) 2009-12-22 2010-12-15 Análogo peptídico de oxintomodulina

Country Status (27)

Country Link
US (1) US8415296B2 (es)
EP (1) EP2515927B1 (es)
JP (1) JP5717758B2 (es)
KR (1) KR101399692B1 (es)
CN (1) CN102665752B (es)
AR (1) AR079344A1 (es)
AU (1) AU2010341650B2 (es)
BR (1) BR112012017054A2 (es)
CA (1) CA2784668C (es)
CL (1) CL2012001685A1 (es)
CO (1) CO6551737A2 (es)
CR (1) CR20120339A (es)
DO (1) DOP2012000175A (es)
EA (1) EA201290557A1 (es)
EC (1) ECSP12011988A (es)
ES (1) ES2512141T3 (es)
GT (1) GT201200205A (es)
HK (1) HK1170943A1 (es)
MA (1) MA33826B1 (es)
MX (1) MX2012007449A (es)
NZ (1) NZ600732A (es)
PE (1) PE20121721A1 (es)
SG (1) SG181872A1 (es)
TN (1) TN2012000303A1 (es)
TW (1) TWI451873B (es)
UA (1) UA106399C2 (es)
WO (1) WO2011087671A1 (es)

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Also Published As

Publication number Publication date
CN102665752A (zh) 2012-09-12
TWI451873B (zh) 2014-09-11
US8415296B2 (en) 2013-04-09
EP2515927A1 (en) 2012-10-31
ECSP12011988A (es) 2012-07-31
CA2784668C (en) 2015-05-05
UA106399C2 (ru) 2014-08-26
DOP2012000175A (es) 2012-08-31
EP2515927B1 (en) 2014-08-06
HK1170943A1 (en) 2013-03-15
SG181872A1 (en) 2012-07-30
AU2010341650A1 (en) 2012-06-07
PE20121721A1 (es) 2012-12-17
KR20120096023A (ko) 2012-08-29
CL2012001685A1 (es) 2012-11-23
MA33826B1 (fr) 2012-12-03
KR101399692B1 (ko) 2014-05-27
MX2012007449A (es) 2012-11-23
AU2010341650B2 (en) 2014-03-27
CN102665752B (zh) 2015-01-21
WO2011087671A1 (en) 2011-07-21
JP5717758B2 (ja) 2015-05-13
TW201143792A (en) 2011-12-16
US20110152181A1 (en) 2011-06-23
NZ600732A (en) 2014-06-27
JP2013515055A (ja) 2013-05-02
EA201290557A1 (ru) 2012-12-28
GT201200205A (es) 2014-04-08
BR112012017054A2 (pt) 2016-11-22
CR20120339A (es) 2012-10-02
CO6551737A2 (es) 2012-10-31
CA2784668A1 (en) 2011-07-21
AR079344A1 (es) 2012-01-18
TN2012000303A1 (en) 2013-12-12

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