ES2506168T3 - Polipéptido que tiene actividad antibacteriana y actividad que induce la angiogénesis y fármacos que contienen dicho polipéptido que curan heridas - Google Patents

Polipéptido que tiene actividad antibacteriana y actividad que induce la angiogénesis y fármacos que contienen dicho polipéptido que curan heridas Download PDF

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Publication number
ES2506168T3
ES2506168T3 ES10780549.1T ES10780549T ES2506168T3 ES 2506168 T3 ES2506168 T3 ES 2506168T3 ES 10780549 T ES10780549 T ES 10780549T ES 2506168 T3 ES2506168 T3 ES 2506168T3
Authority
ES
Spain
Prior art keywords
polypeptide
activity
drugs containing
heal wounds
induces angiogenesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10780549.1T
Other languages
English (en)
Inventor
Takefumi Gemba
Hideki Tomioka
Nao Tamura
Ryoko Sata
Akito Maeda
Akiko Tenma
Toshihide Kanamori
Yoshimi Saito
Shintaro Komaba
Ryuichi Morishita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anges Inc
Original Assignee
Anges MG Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anges MG Inc filed Critical Anges MG Inc
Application granted granted Critical
Publication of ES2506168T3 publication Critical patent/ES2506168T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Un polipéptido cuya secuencia de aminoácidos se muestra en una cualquiera de SEQ ID NOs: 8 y 10; en donde el ácido amino 17º en la SEQ ID NO: 8 es D-Lys y el aminoácido 18º en la SEC ID NO: 10 es D-Lys.

Description

31
41
ES10780549.1T 2009-05-25 2010-05-25 Polipéptido que tiene actividad antibacteriana y actividad que induce la angiogénesis y fármacos que contienen dicho polipéptido que curan heridas Active ES2506168T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009125072 2009-05-25
JP2009125072 2009-05-25
PCT/JP2010/058838 WO2010137594A1 (ja) 2009-05-25 2010-05-25 血管新生誘導活性及び抗菌活性を有するポリペプチドおよびそれを含有する創傷治療剤

Publications (1)

Publication Number Publication Date
ES2506168T3 true ES2506168T3 (es) 2014-10-13

Family

ID=43222702

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10780549.1T Active ES2506168T3 (es) 2009-05-25 2010-05-25 Polipéptido que tiene actividad antibacteriana y actividad que induce la angiogénesis y fármacos que contienen dicho polipéptido que curan heridas

Country Status (5)

Country Link
US (2) US8969311B2 (es)
EP (1) EP2436688B1 (es)
JP (1) JP5750766B2 (es)
ES (1) ES2506168T3 (es)
WO (1) WO2010137594A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9376470B2 (en) 2008-11-28 2016-06-28 Funpep Inc. Polypeptide having angiogenesis-inducing activity and antibacterial activity, and use thereof for medical purposes
JP5750765B2 (ja) 2009-03-06 2015-07-22 株式会社ファンペップ ポリペプチド及びその抗菌または消毒用途
JP6042106B2 (ja) * 2011-06-10 2016-12-14 株式会社ファンペップ メチオニン・スルホキシドを含む新規ポリペプチド
JP6319911B2 (ja) * 2013-03-29 2018-05-09 国立大学法人大阪大学 抗老化作用を有するペプチドおよびその利用
US10112978B2 (en) 2014-09-26 2018-10-30 Osaka University Peptide and use thereof
WO2017164409A1 (ja) * 2016-03-25 2017-09-28 国立大学法人大阪大学 疾患の要因となる生体内タンパク質を標的とするコンジュゲートワクチン

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4939224A (en) 1987-02-26 1990-07-03 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
AU7470400A (en) 1999-08-18 2001-03-13 Regents Of The University Of California, The Cathelicidin-derived peptides with broad spectrum antimicrobial activity
WO2005049819A1 (ja) 2003-10-29 2005-06-02 Toagosei Co., Ltd. 抗菌ペプチド及びその利用
US20050214321A1 (en) 2003-12-01 2005-09-29 Dow Global Technologies Inc. Recombinant icosahedral virus like particle production in pseudomonads
US7807176B2 (en) 2004-03-19 2010-10-05 Genomidea, Inc. Polypeptide promoting vascular endothelial cell growth
US7452856B2 (en) 2004-07-06 2008-11-18 Seikagaku Corporation Antibacterial peptide
SE0402807D0 (sv) 2004-11-17 2004-11-17 Dermagen Ab Novel antimicrobial peptides
US20080025962A1 (en) 2004-11-30 2008-01-31 Angesmg,Inc. Remedy for Alzheimer's Disease
JP4730584B2 (ja) 2004-12-06 2011-07-20 東亞合成株式会社 抗菌ペプチド及びその利用
WO2006132204A1 (ja) 2005-06-06 2006-12-14 Anges Mg, Inc. 転写因子デコイ
JP5134964B2 (ja) 2005-10-05 2013-01-30 ジェノミディア株式会社 単離されたヒト細胞、その取得方法及び用途
US20100167390A1 (en) 2005-12-22 2010-07-01 Toshohiro Nakajima Novel Oligonucleotide and NF-kB Decoy Comprising the Same
WO2008096816A1 (ja) * 2007-02-09 2008-08-14 Genomidea Inc. 血管新生誘導剤及びそれに用いられるポリペプチド
JP5384948B2 (ja) * 2007-02-09 2014-01-08 ジェノミディア株式会社 新規ポリペプチド及びそれを有効成分として含有する抗菌剤
US9376470B2 (en) * 2008-11-28 2016-06-28 Funpep Inc. Polypeptide having angiogenesis-inducing activity and antibacterial activity, and use thereof for medical purposes
JP5750765B2 (ja) 2009-03-06 2015-07-22 株式会社ファンペップ ポリペプチド及びその抗菌または消毒用途

Also Published As

Publication number Publication date
US20150133365A1 (en) 2015-05-14
EP2436688A1 (en) 2012-04-04
JP5750766B2 (ja) 2015-07-22
EP2436688A4 (en) 2013-01-16
US8969311B2 (en) 2015-03-03
EP2436688B1 (en) 2014-07-09
US9695219B2 (en) 2017-07-04
WO2010137594A1 (ja) 2010-12-02
JPWO2010137594A1 (ja) 2012-11-15
US20120172287A1 (en) 2012-07-05

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