ES2312150T3 - Derivados de 4-tetrazolil-4-fenilpiperidina para el tratamiento del dolor. - Google Patents

Derivados de 4-tetrazolil-4-fenilpiperidina para el tratamiento del dolor. Download PDF

Info

Publication number: ES2312150T3
Authority: ES; Spain
Prior art keywords: phenylpiperidine; tetrazolyl; compounds; alkyl; formula
Prior art date: 2002-11-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

ES07006697T

Other languages

English (en)

Spanish (es)

Inventor

Zhengming Chen

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Euro Celtique SA

Original Assignee

Euro Celtique SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-18

Filing date

2003-11-17

Publication date

2009-02-16

2003-11-17 Application filed by Euro Celtique SA filed Critical Euro Celtique SA

2009-02-16 Application granted granted Critical

2009-02-16 Publication of ES2312150T3 publication Critical patent/ES2312150T3/es

2023-11-17 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

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OGPKTRWLBLRODW-UHFFFAOYSA-N 4-phenyl-4-(2h-tetrazol-5-yl)piperidine Chemical compound C1CNCCC1(C=1C=CC=CC=1)C1=NNN=N1 OGPKTRWLBLRODW-UHFFFAOYSA-N 0.000 description 498
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
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- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
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- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

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Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
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ES07006697T 2002-11-18 2003-11-17 Derivados de 4-tetrazolil-4-fenilpiperidina para el tratamiento del dolor. Expired - Lifetime ES2312150T3 (es)

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
US42738102P	2002-11-18	2002-11-18
US427381P		2002-11-18
US46027803P	2003-04-03	2003-04-03
US460278P		2003-04-03
US48848803P	2003-07-17	2003-07-17
US488488P		2003-07-17
US10/714,066 US7202259B2 (en)	2002-11-18	2003-11-13	Therapeutic agents useful for treating pain
US714066		2003-11-13

Publications (1)

Publication Number	Publication Date
ES2312150T3 true ES2312150T3 (es)	2009-02-16

Family

ID=32777221

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES07006697T Expired - Lifetime ES2312150T3 (es)	2002-11-18	2003-11-17	Derivados de 4-tetrazolil-4-fenilpiperidina para el tratamiento del dolor.
ES03789796T Expired - Lifetime ES2285235T3 (es)	2002-11-18	2003-11-17	Derivados de 4-tetrazolil-4-fenilpiperidina para el tratamiento del dolor.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES03789796T Expired - Lifetime ES2285235T3 (es)	2002-11-18	2003-11-17	Derivados de 4-tetrazolil-4-fenilpiperidina para el tratamiento del dolor.

Country Status (37)

Country	Link
US (3)	US7202259B2 (sr)
EP (2)	EP1803718B1 (sr)
JP (2)	JP4601429B2 (sr)
KR (1)	KR20050115221A (sr)
CN (2)	CN100567288C (sr)
AP (1)	AP2210A (sr)
AR (1)	AR047008A1 (sr)
AT (2)	ATE402167T1 (sr)
AU (2)	AU2003294313B2 (sr)
BR (1)	BR0316305A (sr)
CA (1)	CA2506242C (sr)
CO (1)	CO5690588A2 (sr)
CR (2)	CR7877A (sr)
CY (2)	CY1107682T1 (sr)
DE (2)	DE60322451D1 (sr)
DK (2)	DK1562932T3 (sr)
EA (1)	EA008621B1 (sr)
EC (1)	ECSP055840A (sr)
ES (2)	ES2312150T3 (sr)
GE (1)	GEP20084539B (sr)
HK (1)	HK1086829A1 (sr)
IL (1)	IL209352A0 (sr)
IS (2)	IS2720B (sr)
MA (1)	MA27565A1 (sr)
ME (1)	MEP48108A (sr)
MX (1)	MXPA05004669A (sr)
MY (1)	MY135647A (sr)
NI (1)	NI200500087A (sr)
NO (1)	NO20052894D0 (sr)
NZ (2)	NZ572685A (sr)
OA (1)	OA13010A (sr)
PT (2)	PT1562932E (sr)
RS (1)	RS51047B (sr)
SG (1)	SG165998A1 (sr)
SI (2)	SI1803718T1 (sr)
TW (2)	TW200819436A (sr)
WO (1)	WO2004046132A1 (sr)

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2003
- 2003-11-13 US US10/714,066 patent/US7202259B2/en active Active
- 2003-11-17 DK DK03789796T patent/DK1562932T3/da active
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- 2003-11-17 DK DK07006697T patent/DK1803718T3/da active
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- 2003-11-17 NZ NZ572685A patent/NZ572685A/en not_active IP Right Cessation
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- 2003-11-17 SI SI200331358T patent/SI1803718T1/sl unknown
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- 2003-11-17 RS YUP-2005/0375A patent/RS51047B/sr unknown
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- 2003-11-17 CN CN200910173679A patent/CN101648941A/zh active Pending
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2005
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2006
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2007
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2008
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2009
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2010
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Publication number	Publication date
CA2506242A1 (en)	2004-06-03
CR7877A (es)	2005-11-30
TW200418828A (en)	2004-10-01
CY1107682T1 (el)	2013-04-18
EP1803718A1 (en)	2007-07-04
ECSP055840A (es)	2005-08-11
EA200500726A1 (ru)	2005-10-27
KR20050115221A (ko)	2005-12-07
DK1803718T3 (da)	2008-10-27
JP2010163452A (ja)	2010-07-29
NO20052894L (no)	2005-06-14
CR11037A (es)	2009-10-29
ATE402167T1 (de)	2008-08-15
CN101648941A (zh)	2010-02-17
NZ540068A (en)	2007-07-27
AU2010246411A1 (en)	2010-12-16
JP4601429B2 (ja)	2010-12-22
HK1086829A1 (en)	2006-09-29
US20100069437A1 (en)	2010-03-18
PT1803718E (pt)	2008-09-26
TW200819436A (en)	2008-05-01
IS2720B (is)	2011-02-15
CN1711256A (zh)	2005-12-21
ATE358674T1 (de)	2007-04-15
MEP48108A (en)	2011-02-10
US7687518B2 (en)	2010-03-30
ES2285235T3 (es)	2007-11-16
AR047008A1 (es)	2006-01-04
EP1562932B1 (en)	2007-04-04
EP1562932B9 (en)	2007-09-12
US20070179141A1 (en)	2007-08-02
AU2003294313A1 (en)	2004-06-15
OA13010A (en)	2006-11-10
BR0316305A (pt)	2005-09-27
RS20050375A (en)	2007-11-15
US8026254B2 (en)	2011-09-27
DK1562932T3 (da)	2007-08-13
PT1562932E (pt)	2007-07-02
AP2210A (en)	2011-02-25
IL209352A0 (en)	2011-01-31
SI1803718T1 (sl)	2008-12-31
EP1803718B1 (en)	2008-07-23
IS8913A (is)	2010-07-21
DE60313021D1 (de)	2007-05-16
RS51047B (sr)	2010-10-31
CN100567288C (zh)	2009-12-09
DE60322451D1 (de)	2008-09-04
US20040152689A1 (en)	2004-08-05
NZ572685A (en)	2010-06-25
SG165998A1 (en)	2010-11-29
CY1108422T1 (el)	2014-04-09
JP2006525944A (ja)	2006-11-16
CO5690588A2 (es)	2006-10-31
DE60313021T2 (de)	2007-12-13
EA008621B1 (ru)	2007-06-29
AP2005003297A0 (en)	2005-06-30
SI1562932T1 (sl)	2007-08-31
CA2506242C (en)	2011-07-05
EP1562932A1 (en)	2005-08-17
AU2003294313B2 (en)	2010-08-26
GEP20084539B (en)	2008-11-25
NO20052894D0 (no)	2005-06-14
MY135647A (en)	2008-06-30
US7202259B2 (en)	2007-04-10
MXPA05004669A (es)	2005-06-08
WO2004046132A1 (en)	2004-06-03
MA27565A1 (fr)	2005-10-03
TWI343917B (en)	2011-06-21
IS7812A (is)	2005-04-19
NI200500087A (es)	2007-07-24

Publication	Publication Date	Title
ES2312150T3 (es)	2009-02-16	Derivados de 4-tetrazolil-4-fenilpiperidina para el tratamiento del dolor.
ES2312584T3 (es)	2009-03-01	Compuestos de espiropirazol.
ES2316559T3 (es)	2009-04-16	Compuestos espiroindeno y espiroindano.
ES2323876T3 (es)	2009-07-27	Derivados de 1-(4-piperidinil)-1,3-dihidro-2h-benzoxazol-2-ona y compuestos relacionados como analogos de la nociceptina y ligandos de orl1 para el tratamiento del dolor.
ES2340441T3 (es)	2010-06-02	Compuestos de octahidrobencimidazolona como analgesicos.
US7414062B2 (en)	2008-08-19	Triazaspiro compounds useful for treating or preventing pain
JP2005506302A (ja)	2005-03-03	ノシセプチン類似体
ES2382712T3 (es)	2012-06-12	Compuestos de 4-oxadiazolil-piperidina y uso de los mismos