ES2196640T3 - Dispositivo terapeutico transdermico con capsaicina y analogos de capsaicina. - Google Patents
Dispositivo terapeutico transdermico con capsaicina y analogos de capsaicina.Info
- Publication number
- ES2196640T3 ES2196640T3 ES98962908T ES98962908T ES2196640T3 ES 2196640 T3 ES2196640 T3 ES 2196640T3 ES 98962908 T ES98962908 T ES 98962908T ES 98962908 T ES98962908 T ES 98962908T ES 2196640 T3 ES2196640 T3 ES 2196640T3
- Authority
- ES
- Spain
- Prior art keywords
- capsaicine
- analogs
- therapeutic device
- capsaicin
- transdermal therapeutic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Un parche transdérmico para el tratamiento del dolor neuropático en un paciente humano, comprendiendo dicho parche una formulación que comprende capsaicina, un análogo de capsaicina o una mezcla de los mismos, a una concentración total de más de 5% en peso a 10% en peso de la formulación.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/990,633 US6239180B1 (en) | 1995-11-08 | 1997-12-15 | Transdermal therapeutic device and method with capsaicin and capsaicin analogs |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2196640T3 true ES2196640T3 (es) | 2003-12-16 |
Family
ID=25536360
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES03005137T Expired - Lifetime ES2272827T3 (es) | 1997-12-15 | 1998-12-08 | Parche terapeutico transdermico con capsaicina y analogos de capsaicina. |
ES98962908T Expired - Lifetime ES2196640T3 (es) | 1997-12-15 | 1998-12-08 | Dispositivo terapeutico transdermico con capsaicina y analogos de capsaicina. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES03005137T Expired - Lifetime ES2272827T3 (es) | 1997-12-15 | 1998-12-08 | Parche terapeutico transdermico con capsaicina y analogos de capsaicina. |
Country Status (11)
Country | Link |
---|---|
US (2) | US6239180B1 (es) |
EP (2) | EP1039802B1 (es) |
AT (2) | ATE344023T1 (es) |
CA (1) | CA2314326C (es) |
CY (1) | CY1107582T1 (es) |
DE (2) | DE69836352T2 (es) |
DK (2) | DK1316308T3 (es) |
ES (2) | ES2272827T3 (es) |
HK (1) | HK1030853A1 (es) |
PT (1) | PT1039802E (es) |
WO (1) | WO1999030560A1 (es) |
Families Citing this family (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6239180B1 (en) * | 1995-11-08 | 2001-05-29 | The Regents Of The University Of California | Transdermal therapeutic device and method with capsaicin and capsaicin analogs |
US6383511B1 (en) * | 1999-10-25 | 2002-05-07 | Epicept Corporation | Local prevention or amelioration of pain from surgically closed wounds |
GB2355934B (en) * | 1999-11-05 | 2003-11-05 | Lohmann Gmbh & Co Kg | Wound dressing |
AUPQ622600A0 (en) * | 2000-03-15 | 2000-04-06 | Unisearch Limited | Treatment and/or prevention of ocular pain |
DE10056009A1 (de) * | 2000-11-11 | 2002-05-16 | Beiersdorf Ag | Hautfreundliches Wirkstoffpflaster zur transdermalen Verabreichung hyperämisierender Wirkstoffe |
WO2003015698A2 (en) * | 2001-08-13 | 2003-02-27 | University Of Pittsburgh | Application of lipid vehicles and use for drug delivery |
US8110217B2 (en) * | 2001-08-13 | 2012-02-07 | University Of Pittsburgh | Sphingomyelin liposomes for the treatment of hyperactive bladder disorders |
EP1450824A4 (en) * | 2001-11-02 | 2005-09-28 | Elan Corp Plc | PHARMACEUTICAL COMPOSITION |
PT1539124T (pt) * | 2002-09-05 | 2018-10-22 | Vanderbilt Royalty Sub L P | Composições e kits para a remoção de compostos irritantes de superfícies corporais |
CA2499994C (en) * | 2002-09-23 | 2012-07-10 | Verion, Inc. | Abuse-resistant pharmaceutical compositions |
US7687080B2 (en) * | 2002-11-25 | 2010-03-30 | Taraxos Inc. | Treatment of neuropathy |
WO2004058286A1 (en) | 2002-12-18 | 2004-07-15 | Algorx Pharmaceuticals, Inc. | Administration of capsaicinoids |
WO2004056305A2 (en) * | 2002-12-18 | 2004-07-08 | Algorx | Administration of capsaicinoids |
US7235270B2 (en) | 2003-03-10 | 2007-06-26 | Mayeux Jerry V | Pain balm |
NZ542887A (en) * | 2003-04-08 | 2008-05-30 | Algorx Pharmaceuticals Inc | Preparation and purification of synthetic capsaicin |
EP1610742B1 (en) | 2003-04-10 | 2015-01-21 | Neurogesx, Inc. | Uses and compositions for administration of capsaicin |
NZ541956A (en) | 2003-04-14 | 2008-09-26 | Lohmann Therapie Syst Lts | Therapeutic patch with polysiloxane matrix comprising capsaicin |
DE102004009904A1 (de) * | 2004-02-26 | 2005-09-22 | Grünenthal GmbH | Kit aus einem gegebenenfalls wirkstoffhaltigen Pflaster und einem Hautirritationen verhindernden Mittel |
AU2005249572A1 (en) * | 2004-06-02 | 2005-12-15 | Neurogesx, Inc. | Formulations comprising a capsaicinoid a local anesthetic and/or an antipruritic agent for the treatment of pain |
US7704522B2 (en) * | 2004-09-08 | 2010-04-27 | Clyde Morgan | Topical medicament |
EP1827405A2 (en) * | 2004-11-24 | 2007-09-05 | Algorx Pharmaceuticals, Inc. | Capsaicinoid gel formulation and uses thereof |
JP2006206471A (ja) * | 2005-01-26 | 2006-08-10 | Nitto Denko Corp | テープ製剤 |
EP1858495A2 (en) * | 2005-02-14 | 2007-11-28 | Neurogesx, Inc. | Device for delivery of trpv1 agonists |
WO2006099541A2 (en) * | 2005-03-15 | 2006-09-21 | Richard Daniel Carliss | Therapeutic wound care product |
EP1865933B1 (en) * | 2005-03-30 | 2015-11-04 | Vanderbilt Royalty Sub L.P. | Low-concentration capsaicin patch and methods for treating neuropathic pain |
EP1865941B8 (en) * | 2005-04-01 | 2010-12-22 | Neurogesx, Inc. | Oils of capsaicinoids and methods of making and using the same |
US7282224B1 (en) | 2006-06-09 | 2007-10-16 | Guthy-Renker Corporation | Pain relief composition |
US7943666B2 (en) * | 2006-07-24 | 2011-05-17 | Trinity Laboratories, Inc. | Esters of capsaicin for treating pain |
US7645767B2 (en) * | 2006-08-31 | 2010-01-12 | Trinity Laboratories, Inc. | Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy |
US20080107747A1 (en) * | 2006-10-23 | 2008-05-08 | Roederer Joy E | Pain relief composition |
KR101572634B1 (ko) | 2008-04-04 | 2015-12-01 | 포사이트 비젼4, 인크. | 통증 관리 및 시력을 위한 치료 장치 |
US8987328B2 (en) * | 2008-10-30 | 2015-03-24 | Trinity Laboratories, Inc. | Esters of capsaicinoids as dietary supplements |
EP2490620A4 (en) | 2009-10-23 | 2017-03-22 | Forsight Labs, Llc | Conformable therapeutic shield for vision and pain |
EP2490635B1 (en) | 2009-10-23 | 2017-09-06 | Nexisvision, Inc. | Corneal denervation for treatment of ocular pain |
US8591025B1 (en) | 2012-09-11 | 2013-11-26 | Nexisvision, Inc. | Eye covering and refractive correction methods for LASIK and other applications |
KR20130107321A (ko) | 2010-10-25 | 2013-10-01 | 넥시스비젼, 인코포레이티드 | 시력용 눈 보호막을 인식하기 위한 방법 및 장치 |
AU2012249773A1 (en) | 2011-04-28 | 2013-11-07 | Nexisvision, Inc. | Eye covering and refractive correction methods and apparatus having improved tear flow, comfort, and/or applicability |
JP6228540B2 (ja) | 2011-09-09 | 2017-11-08 | ヴィズリ・ヘルス・サイエンスィズ・エルエルシー | Trpv1選択的アゴニストを含む疼痛軽減組成物、ならびにその製造および使用 |
US9465233B2 (en) | 2012-04-20 | 2016-10-11 | Nexisvision, Inc. | Bimodular contact lenses |
CN104335104B (zh) | 2012-04-20 | 2017-06-09 | 内希斯视觉股份有限公司 | 用于屈光矫正的接触透镜 |
WO2013175357A2 (en) | 2012-05-23 | 2013-11-28 | Mahesh Kandula | Compositions and methods for the treatment of inflammatory bowel disease |
EP2852569B1 (en) | 2012-05-23 | 2020-10-14 | Cellixbio Private Limited | Compositions and methods for the treatment of multiple sclerosis |
JP6310072B2 (ja) | 2013-06-26 | 2018-04-11 | ネクシスビジョン, インコーポレイテッド | 屈折矯正のためのコンタクトレンズ |
US9341864B2 (en) | 2013-11-15 | 2016-05-17 | Nexisvision, Inc. | Contact lenses having a reinforcing scaffold |
WO2015116559A1 (en) | 2014-01-29 | 2015-08-06 | Nexisvision, Inc. | Multifocal bimodulus contact lenses |
BR112016023815A2 (pt) | 2014-04-15 | 2017-08-15 | Vizuri Health Sciences Llc | composições tópicas para o alívio da dor, produção e uso |
CA2976314C (en) | 2014-09-26 | 2021-02-23 | Cellix Bio Private Limited | Compositions and methods for the treatment of epilepsy and neurological disorders |
CA2967908C (en) | 2014-09-29 | 2020-11-17 | Mahesh Kandula | Compositions and methods for the treatment of multiple sclerosis |
WO2016098119A1 (en) | 2014-10-27 | 2016-06-23 | Cellix Bio Private Limited | Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis |
WO2016067297A1 (en) | 2014-10-27 | 2016-05-06 | Cellix Bio Private Limited | Salts of valproic acid with piperazine, ethylenediamine, lysine and/or eicosapentaenoic ecid (epa) amine derivatives for the treatment of epilepsy |
CA2969330A1 (en) | 2014-12-01 | 2016-06-09 | Cellix Bio Private Limited | Compositions and methods for the treatment of multiple sclerosis |
JP6698669B2 (ja) | 2015-02-09 | 2020-05-27 | セリックス バイオ プライヴェート リミテッドCellix Bio Private Limited | 粘膜炎の治療のための組成物及び方法 |
WO2017020125A1 (en) | 2015-07-31 | 2017-02-09 | Delivra Inc. | Transdermal formulations for delivery of capsaicinoids |
RU2751770C2 (ru) | 2016-08-11 | 2021-07-16 | Селликс Био Прайвет Лимитед | Композиции и способы лечения синдрома раздраженного кишечника |
DK3522873T3 (da) | 2016-10-04 | 2022-06-20 | Cellix Bio Private Ltd | Sammensætninger og fremgangsmåder til behandlingen af xerostomi |
EP3554494A4 (en) | 2016-12-19 | 2021-02-17 | Cellixbio Private Limited | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION |
WO2019023605A1 (en) | 2017-07-27 | 2019-01-31 | Allergan, Inc. | PROSTACYCLINE RECEPTOR AGONISTS FOR BODY GREASE REDUCTION |
RU2761436C1 (ru) | 2017-11-17 | 2021-12-08 | Целликс Био Прайвет Лимитед | Композиции и способы лечения нарушений со стороны органа зрения |
RU2020119228A (ru) | 2017-11-17 | 2021-12-20 | Целликс Био Прайвет Лимитед | Соединения, композиции и способы лечения нарушений со стороны органа зрения и заболеваний кожи |
EP4121027A1 (en) | 2020-03-17 | 2023-01-25 | Grünenthal GmbH | Repeated topical application of capsaicin patch for treating initial non-responders |
KR20220164022A (ko) | 2020-04-03 | 2022-12-12 | 그뤼넨탈 게엠베하 | 캡사이신 패치의 반복된 국소 적용 요법 |
RU2755206C1 (ru) | 2020-05-20 | 2021-09-14 | Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) | Средство пролонгированного анальгетического действия и лекарственный препарат на его основе |
US11234947B2 (en) * | 2020-06-30 | 2022-02-01 | Imperial College Innovations Limited | Treatment of peripheral neuropathy induced by cancer chemotherapy |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4486450B1 (en) | 1980-07-14 | 1998-07-28 | Joel E Bernstein | Method of treating psoriatic skin and composition |
US4313958A (en) | 1980-10-24 | 1982-02-02 | The Procter & Gamble Company | Method of producing analgesia |
US4424205A (en) | 1982-03-18 | 1984-01-03 | The Procter & Gamble Company | Hydroxyphenylacetamides having analgesic and anti-irritant activity |
US4536404A (en) | 1983-06-16 | 1985-08-20 | Dermatological Enterprises, Ltd. | Method and composition for treating post-herpetic neuralgia |
US4532139A (en) | 1983-07-14 | 1985-07-30 | The Procter & Gamble Company | Compounds and compositions useful for producing analgesia |
US4544668A (en) | 1983-07-14 | 1985-10-01 | The Procter & Gamble Company | Compounds and compositions useful for producing analgesia |
US4544669A (en) | 1983-07-14 | 1985-10-01 | The Procter & Gamble Company | Compounds and compositions useful for producing analgesia |
US4592912A (en) | 1983-10-31 | 1986-06-03 | Harriet Nickolaus | Ache and pain relieving and preventing composition |
US4681897A (en) | 1984-01-16 | 1987-07-21 | The Procter & Gamble Company | Pharmaceutical products providing enhanced analgesia |
US4898887A (en) * | 1984-12-20 | 1990-02-06 | The Procter & Gamble Company | Compounds and compositions having anti-inflammatory and analgesic activity |
US4971800A (en) | 1988-07-08 | 1990-11-20 | The Regents Of The University Of California | Method and compositions for enhancing the cutaneous penetration of pharmacologically active agents |
US4939149A (en) | 1988-10-24 | 1990-07-03 | The United States Of America As Represented By The Department Of Health And Human Services | Resiniferatoxin and analogues thereof to cause sensory afferent C-fiber and thermoregulatory desensitization |
US4997853A (en) | 1988-12-02 | 1991-03-05 | Galenpharma, Inc. | Method and compositions utilizing capsaicin as an external analgesic |
CA1338779C (en) | 1989-03-17 | 1996-12-10 | Harry Hind | Method for treating pain associated with herpes-zoster and post-herpetic neuralgia by topical application of local anesthetics |
US5411738A (en) | 1989-03-17 | 1995-05-02 | Hind Health Care, Inc. | Method for treating nerve injury pain associated with shingles (herpes-zoster and post-herpetic neuralgia) by topical application of lidocaine |
AU5744490A (en) | 1989-05-15 | 1990-12-18 | Afferon Corporation | Composition and method for neural desensitization |
US5063060A (en) | 1989-12-19 | 1991-11-05 | Cisco Limited Partnership | Compositions and method for treating painful, inflammatory or allergic disorders |
JP2748199B2 (ja) * | 1991-08-27 | 1998-05-06 | 泰一郎 岩倉 | 気管支喘息発作の予防と治療貼付剤 |
US5260313A (en) | 1992-03-12 | 1993-11-09 | National Pain Institute, Inc. | Diagnosis and treatment of various neuralgias |
US5431914A (en) | 1992-04-17 | 1995-07-11 | Adekunle; Michael | Method of treating an internal condition by external application of capsaicin without the need for systemic absorption |
JP3414423B2 (ja) * | 1992-11-27 | 2003-06-09 | 積水化学工業株式会社 | 眠気防止用外用剤及び貼付剤 |
US5665360A (en) | 1993-05-14 | 1997-09-09 | Mann; Richard H. | Method of treating peripheral neuropathies of the feet and legs |
US5910512A (en) | 1994-04-18 | 1999-06-08 | Healthline Laboratories, Inc. | Topical analgesic using water soluble capsaicin |
DE4414502A1 (de) * | 1994-04-26 | 1995-11-02 | Edda Scholten | Salbe zur äußerlichen Anwendung bei Schmerzen |
US5665378A (en) | 1994-09-30 | 1997-09-09 | Davis; Roosevelt | Transdermal therapeutic formulation |
US5762963A (en) | 1995-06-07 | 1998-06-09 | Emory University | Method and compositions for controlling oral and pharyngeal pain using capsaicinoids |
US5788982A (en) | 1995-06-16 | 1998-08-04 | Nadoolman; Wolffe | Method and composition for treating oral pain using capsaicin |
US6239180B1 (en) * | 1995-11-08 | 2001-05-29 | The Regents Of The University Of California | Transdermal therapeutic device and method with capsaicin and capsaicin analogs |
US5854291A (en) | 1996-04-23 | 1998-12-29 | Medical Merchandising, Inc. | Pain reliever and method of use |
US5856361A (en) | 1996-04-23 | 1999-01-05 | Medical Merchandising, Inc. | Pain reliever and method of use |
US5869533A (en) | 1996-04-23 | 1999-02-09 | Holt; Stephen D. | Non-irritating capsaicin formulations and applicators therefor |
ATE219674T1 (de) | 1997-03-13 | 2002-07-15 | James N Campbell | Zusammensetzung enthaltend capsaicin oder seine analogen und lokalanästhetika |
CA2309903C (en) | 1998-01-22 | 2012-03-27 | The Regents Of The University Of California | Nucleic acid sequences encoding capsaicin receptor |
MXPA00008273A (es) | 1998-02-24 | 2002-04-24 | Univ Wake Forest | Metodo para el tratamiento del dolor, incluyendo el dolor cronico y especifico de la mujer. |
-
1997
- 1997-12-15 US US08/990,633 patent/US6239180B1/en not_active Expired - Lifetime
-
1998
- 1998-12-08 DE DE69836352T patent/DE69836352T2/de not_active Expired - Lifetime
- 1998-12-08 WO PCT/US1998/025794 patent/WO1999030560A1/en active IP Right Grant
- 1998-12-08 CA CA002314326A patent/CA2314326C/en not_active Expired - Lifetime
- 1998-12-08 EP EP98962908A patent/EP1039802B1/en not_active Expired - Lifetime
- 1998-12-08 AT AT03005137T patent/ATE344023T1/de active
- 1998-12-08 AT AT98962908T patent/ATE240723T1/de active
- 1998-12-08 ES ES03005137T patent/ES2272827T3/es not_active Expired - Lifetime
- 1998-12-08 ES ES98962908T patent/ES2196640T3/es not_active Expired - Lifetime
- 1998-12-08 EP EP03005137A patent/EP1316308B1/en not_active Expired - Lifetime
- 1998-12-08 PT PT98962908T patent/PT1039802E/pt unknown
- 1998-12-08 DK DK03005137T patent/DK1316308T3/da active
- 1998-12-08 DK DK98962908T patent/DK1039802T3/da active
- 1998-12-08 DE DE69814917T patent/DE69814917T2/de not_active Expired - Lifetime
-
2001
- 2001-01-25 US US09/769,596 patent/US20010002406A1/en not_active Abandoned
- 2001-02-28 HK HK01101441A patent/HK1030853A1/xx not_active IP Right Cessation
-
2007
- 2007-01-25 CY CY20071100093T patent/CY1107582T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2314326A1 (en) | 1999-06-24 |
DE69814917T2 (de) | 2004-02-12 |
ATE344023T1 (de) | 2006-11-15 |
CA2314326C (en) | 2008-11-18 |
EP1316308A1 (en) | 2003-06-04 |
EP1039802A1 (en) | 2000-10-04 |
ATE240723T1 (de) | 2003-06-15 |
US20010002406A1 (en) | 2001-05-31 |
DE69836352T2 (de) | 2007-05-24 |
EP1316308B1 (en) | 2006-11-02 |
DK1039802T3 (da) | 2003-09-22 |
US6239180B1 (en) | 2001-05-29 |
DE69814917D1 (de) | 2003-06-26 |
DE69836352D1 (de) | 2006-12-14 |
ES2272827T3 (es) | 2007-05-01 |
DK1316308T3 (da) | 2007-03-05 |
EP1039802A4 (en) | 2002-01-23 |
EP1039802B1 (en) | 2003-05-21 |
PT1039802E (pt) | 2003-10-31 |
HK1030853A1 (en) | 2001-05-25 |
WO1999030560A1 (en) | 1999-06-24 |
CY1107582T1 (el) | 2013-03-13 |
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