ES2192014T3 - Formulaciones de clorhexidina y nuevas sales de clorhexidina. - Google Patents
Formulaciones de clorhexidina y nuevas sales de clorhexidina.Info
- Publication number
- ES2192014T3 ES2192014T3 ES99123468T ES99123468T ES2192014T3 ES 2192014 T3 ES2192014 T3 ES 2192014T3 ES 99123468 T ES99123468 T ES 99123468T ES 99123468 T ES99123468 T ES 99123468T ES 2192014 T3 ES2192014 T3 ES 2192014T3
- Authority
- ES
- Spain
- Prior art keywords
- chlorhexidine
- acid
- lactone
- gamma
- formulations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
Abstract
Formulación de clorhexidina en forma de una mezcla pulverulenta hidrosoluble, compuesta por base de clorhexidina, uno o más ácidos sacáricos o sus lactonas de la serie de ácido glucónico o gluconolactona, ácido lactobiónico (I), D-galacton-gamma-lactona (II), ácido L-manónico-gamma-lactona (III), ácido D-(-)-gulónicory-lactona (IV), ácido D-(+)-galacturónico (V) y ácido alfa-D-hepta-glucónico-gamma-lactona (VI), en la cual la relación molar de base de clorhexidina a ácido sacárico o una lactona del mismo es 1 a igual o mayor que 2, y 0 hasta 10 % en peso de coadyuvantes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19857151A DE19857151A1 (de) | 1998-12-11 | 1998-12-11 | Chlorhexidin-Formulierungen, neue Chlorhexidinsalze, sie enthaltende Lösungen und deren Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2192014T3 true ES2192014T3 (es) | 2003-09-16 |
Family
ID=7890710
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES99123468T Expired - Lifetime ES2192014T3 (es) | 1998-12-11 | 1999-11-25 | Formulaciones de clorhexidina y nuevas sales de clorhexidina. |
Country Status (12)
Country | Link |
---|---|
US (1) | US6500466B2 (es) |
EP (1) | EP1018337B1 (es) |
JP (1) | JP2000178189A (es) |
AU (1) | AU751521B2 (es) |
BR (1) | BR9905832A (es) |
CA (1) | CA2292226C (es) |
DE (2) | DE19857151A1 (es) |
DK (1) | DK1018337T3 (es) |
ES (1) | ES2192014T3 (es) |
IL (1) | IL133395A (es) |
PL (1) | PL200514B1 (es) |
ZA (1) | ZA997575B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10052322A1 (de) | 2000-10-21 | 2002-05-02 | Degussa | Wasserlösliche chlorhexidinhaltige Zusammensetzungen und deren Verwendung |
GB0211576D0 (en) * | 2002-05-21 | 2002-06-26 | Cheetham J K | A novel formula for modification of chemical compounds on flavour solubility and stability |
US7074459B2 (en) * | 2003-05-23 | 2006-07-11 | Stockel Richard F | Method for preserving wood |
US20050114266A1 (en) * | 2003-11-26 | 2005-05-26 | Lingan Satkunanathan | System and method for managing licenses using interactive wizards |
JP2009545783A (ja) * | 2006-07-31 | 2009-12-24 | 株式会社東芝 | 不揮発性メモリシステム、及びそのデータ読み出し/書き込み制御方法 |
WO2010080936A2 (en) | 2009-01-07 | 2010-07-15 | Entrotech, Inc. | Chlorhexidine-containing antimicrobial laminates |
US20130065965A1 (en) * | 2009-11-18 | 2013-03-14 | Medichem S.A. | Di(4-chloro-phenyldiguanido) derivative which is free of potential genotoxicity and a process for reducing the residual amount of p-chloroaniline in said di(4-chloro-phenyldiguanido) derivative |
WO2012100244A2 (en) | 2011-01-21 | 2012-07-26 | Avery Dennison Corporation | Chlorhexidine gluconate containing solvent adhesive |
EP2710085B1 (en) | 2011-05-16 | 2018-09-26 | Avery Dennison Corporation | Adhesive containing microparticles |
WO2014124232A2 (en) | 2013-02-07 | 2014-08-14 | Avery Dennison Corporation | Antimicrobial adhesives having improved properties |
US11213432B2 (en) | 2013-03-15 | 2022-01-04 | Avery Dennison Corporation | Transparent cover dressing application system and inclusion of label strip |
EP3131540B1 (en) | 2014-04-18 | 2023-11-22 | Entrotech, Inc. | Methods of processing chlorhexidine-containing polymerizable compositions and antimicrobial articles formed thereby |
JP6338435B2 (ja) * | 2014-04-25 | 2018-06-06 | 日本ゼトック株式会社 | 皮膚外用剤 |
US11337940B2 (en) | 2014-06-05 | 2022-05-24 | Avery Dennison Corporation | Articles with active agent concentrated at the substrate contacting surface and related methods |
RU2696259C2 (ru) * | 2017-10-23 | 2019-08-01 | Общество С Ограниченной Ответственностью "Сан Системз" | Солюбилизация хлоргексидина основания, антисептическая и дезинфицирующая композиции |
DE102019000322A1 (de) | 2019-01-14 | 2020-07-16 | Beuth Hochschule Für Technik Berlin | Polymerzusammensetzung mit antiseptischen Eigenschaften und Verfahren zur Herstellung |
DE102019000321A1 (de) | 2019-01-14 | 2020-07-16 | Beuth Hochschule Für Technik Berlin | Orale Polymerzusammensetzung mit verzögerter Freisetzung |
US20240197938A1 (en) * | 2021-01-04 | 2024-06-20 | Harcros Chemicals, Inc. | Antimicrobial compounds based on glucoheptonic acids and their salts |
CN114391550B (zh) * | 2022-01-06 | 2022-11-22 | 江南大学 | 一种水溶性氯己定类抗菌剂及其制备方法和应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5726612A (en) * | 1980-07-24 | 1982-02-12 | Lion Corp | Preparation of oral composition |
GB8427499D0 (en) * | 1984-10-31 | 1984-12-05 | Stafford Miller Ltd | Oral hygiene products |
JPS61130210A (ja) * | 1984-11-28 | 1986-06-18 | Sunstar Inc | クロルヘキシジンを安定に配合したパスタ |
FR2579979B1 (es) * | 1985-04-05 | 1987-06-26 | Pf Cosmetique | |
US5389677B1 (en) * | 1986-12-23 | 1997-07-15 | Tristrata Inc | Method of treating wrinkles using glycalic acid |
US6051609A (en) * | 1997-09-09 | 2000-04-18 | Tristrata Technology, Inc. | Additives enhancing the effect of therapeutic agents |
SE465905B (sv) * | 1989-03-15 | 1991-11-18 | Gunnar Roella | Tandvaardsmedel som innehaaller ett acetat- eller glukonatsalt av en antimikrobiell bisbiguanid |
JP3305108B2 (ja) * | 1994-03-30 | 2002-07-22 | サンスター株式会社 | 歯磨組成物 |
JPH09301858A (ja) * | 1996-05-13 | 1997-11-25 | Senju Pharmaceut Co Ltd | グルコン酸クロルヘキシジン安定化水性薬剤 |
FR2752731B1 (fr) * | 1996-08-28 | 2001-04-27 | Pioch Michel | Composition utile notamment en chirurgie dentaire |
US5877212A (en) * | 1997-04-16 | 1999-03-02 | Yu; Ruey J. | Molecular complex and control-release of alpha hydroxyacids |
-
1998
- 1998-12-11 DE DE19857151A patent/DE19857151A1/de not_active Withdrawn
-
1999
- 1999-11-25 EP EP99123468A patent/EP1018337B1/de not_active Expired - Lifetime
- 1999-11-25 ES ES99123468T patent/ES2192014T3/es not_active Expired - Lifetime
- 1999-11-25 DE DE59904218T patent/DE59904218D1/de not_active Expired - Lifetime
- 1999-11-25 DK DK99123468T patent/DK1018337T3/da active
- 1999-12-09 ZA ZA9907575A patent/ZA997575B/xx unknown
- 1999-12-09 IL IL13339599A patent/IL133395A/en not_active IP Right Cessation
- 1999-12-10 JP JP11352069A patent/JP2000178189A/ja not_active Ceased
- 1999-12-10 AU AU64454/99A patent/AU751521B2/en not_active Ceased
- 1999-12-10 CA CA002292226A patent/CA2292226C/en not_active Expired - Fee Related
- 1999-12-10 PL PL337107A patent/PL200514B1/pl unknown
- 1999-12-13 BR BR9905832-4A patent/BR9905832A/pt not_active Application Discontinuation
- 1999-12-13 US US09/458,717 patent/US6500466B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
PL337107A1 (en) | 2000-06-19 |
US20020018814A1 (en) | 2002-02-14 |
AU751521B2 (en) | 2002-08-22 |
PL200514B1 (pl) | 2009-01-30 |
CA2292226A1 (en) | 2000-06-11 |
DE59904218D1 (de) | 2003-03-13 |
CA2292226C (en) | 2009-02-10 |
IL133395A0 (en) | 2001-04-30 |
IL133395A (en) | 2004-06-20 |
EP1018337A2 (de) | 2000-07-12 |
BR9905832A (pt) | 2000-08-29 |
EP1018337B1 (de) | 2003-02-05 |
JP2000178189A (ja) | 2000-06-27 |
DE19857151A1 (de) | 2000-06-15 |
ZA997575B (en) | 2000-06-12 |
AU6445499A (en) | 2000-06-15 |
EP1018337A3 (de) | 2001-01-03 |
DK1018337T3 (da) | 2003-05-05 |
US6500466B2 (en) | 2002-12-31 |
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