ES2189154T3 - Composiciones oftalmicas polimerizables in vivo. - Google Patents
Composiciones oftalmicas polimerizables in vivo.Info
- Publication number
- ES2189154T3 ES2189154T3 ES98915491T ES98915491T ES2189154T3 ES 2189154 T3 ES2189154 T3 ES 2189154T3 ES 98915491 T ES98915491 T ES 98915491T ES 98915491 T ES98915491 T ES 98915491T ES 2189154 T3 ES2189154 T3 ES 2189154T3
- Authority
- ES
- Spain
- Prior art keywords
- ophthalmic compositions
- vivo
- polymerizable ophthalmic
- vivo polymerizable
- fluorophobic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
- C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
- C08F20/04—Acids, Metal salts or ammonium salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/25—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
- C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
- C08F20/10—Esters
- C08F20/22—Esters containing halogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F22/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides or nitriles thereof
- C08F22/10—Esters
- C08F22/1006—Esters of polyhydric alcohols or polyhydric phenols, e.g. ethylene glycol dimethacrylate
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/3154—Of fluorinated addition polymer from unsaturated monomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Materials For Medical Uses (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Paints Or Removers (AREA)
- Medicinal Preparation (AREA)
- Prostheses (AREA)
Abstract
Esta invención se refiere a composiciones oftálmicas que contienen sustancias de mesofase anfipáticas polimerizables bioadhesivas y biocompatibles, que sirven para reparar los desgarros de los tejidos de la retina o los desprendimientos de la retina. En un modo de realización, estas sustancias polimerizables, que contienen monómeros fluoroalquilo o perfluoroalquilo sustituidos que presentan funciones de agentes tensioactivos aniónico, catiónico y/o iónico en los extremos fluorófobos insaturados, se polimerizan in vivo para garantizar una distribución eficaz de larga duración de los tejidos de la retina desgarrados, rotos o desprendidos. Las aplicaciones oftálmicas de estas sustancias no se limitan a la reparación de la retina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/833,635 US5858345A (en) | 1996-04-08 | 1997-04-08 | In vivo polymerizable ophthalmic compositions |
US09/012,836 US6124037A (en) | 1996-04-08 | 1998-01-23 | Articles coated with in vivo polymerizable ophthalmic compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2189154T3 true ES2189154T3 (es) | 2003-07-01 |
Family
ID=26684066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98915491T Expired - Lifetime ES2189154T3 (es) | 1997-04-08 | 1998-04-07 | Composiciones oftalmicas polimerizables in vivo. |
Country Status (11)
Country | Link |
---|---|
US (1) | US6124037A (es) |
EP (1) | EP0973514B1 (es) |
JP (1) | JP2001519816A (es) |
AT (1) | ATE233555T1 (es) |
AU (1) | AU725045B2 (es) |
CA (1) | CA2272625A1 (es) |
DE (1) | DE69811875T2 (es) |
DK (1) | DK0973514T3 (es) |
ES (1) | ES2189154T3 (es) |
PT (1) | PT973514E (es) |
WO (1) | WO1998044915A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2305349A1 (en) * | 1997-10-27 | 1999-05-06 | Alexander R. Irvine | Methods and pharmaceutical compositions for the closure of retinal breaks |
JP5915222B2 (ja) | 2012-02-09 | 2016-05-11 | 株式会社Ihi | 内径測定装置 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5527356A (en) * | 1994-08-02 | 1996-06-18 | Syntec, Inc. | Retinal plug |
DE19532408A1 (de) * | 1995-09-01 | 1997-03-06 | Basf Ag | Polymerisierbare flüssigkristalline Verbindungen |
US5858345A (en) * | 1996-04-08 | 1999-01-12 | Alcon Laboratories, Inc. | In vivo polymerizable ophthalmic compositions |
US5905127A (en) * | 1996-04-08 | 1999-05-18 | The University Of Southern Mississippi | Polymerizable mesophases based on substituted unsaturated carboxylic acids |
-
1998
- 1998-01-23 US US09/012,836 patent/US6124037A/en not_active Expired - Fee Related
- 1998-04-07 CA CA 2272625 patent/CA2272625A1/en not_active Abandoned
- 1998-04-07 JP JP54317098A patent/JP2001519816A/ja not_active Ceased
- 1998-04-07 DK DK98915491T patent/DK0973514T3/da active
- 1998-04-07 AT AT98915491T patent/ATE233555T1/de not_active IP Right Cessation
- 1998-04-07 WO PCT/US1998/007280 patent/WO1998044915A1/en active IP Right Grant
- 1998-04-07 AU AU69663/98A patent/AU725045B2/en not_active Ceased
- 1998-04-07 EP EP19980915491 patent/EP0973514B1/en not_active Expired - Lifetime
- 1998-04-07 DE DE69811875T patent/DE69811875T2/de not_active Expired - Fee Related
- 1998-04-07 PT PT98915491T patent/PT973514E/pt unknown
- 1998-04-07 ES ES98915491T patent/ES2189154T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1998044915A1 (en) | 1998-10-15 |
JP2001519816A (ja) | 2001-10-23 |
DE69811875T2 (de) | 2003-08-28 |
EP0973514A1 (en) | 2000-01-26 |
CA2272625A1 (en) | 1998-10-15 |
AU725045B2 (en) | 2000-10-05 |
DE69811875D1 (de) | 2003-04-10 |
EP0973514B1 (en) | 2003-03-05 |
DK0973514T3 (da) | 2003-06-23 |
US6124037A (en) | 2000-09-26 |
AU6966398A (en) | 1998-10-30 |
PT973514E (pt) | 2003-06-30 |
ATE233555T1 (de) | 2003-03-15 |
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