ES2183999T3 - Estabilizacion de bilirrubina en sueros de control y en calibradores. - Google Patents

Estabilizacion de bilirrubina en sueros de control y en calibradores.

Info

Publication number
ES2183999T3
ES2183999T3 ES97104679T ES97104679T ES2183999T3 ES 2183999 T3 ES2183999 T3 ES 2183999T3 ES 97104679 T ES97104679 T ES 97104679T ES 97104679 T ES97104679 T ES 97104679T ES 2183999 T3 ES2183999 T3 ES 2183999T3
Authority
ES
Spain
Prior art keywords
bilirubin
iii
alkyl
bilirrubine
calibrators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97104679T
Other languages
English (en)
Inventor
Geoffrey Dr Burns
Martina Dr Junius-Comer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1996111458 external-priority patent/DE19611458A1/de
Priority claimed from DE1996123955 external-priority patent/DE19623955A1/de
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of ES2183999T3 publication Critical patent/ES2183999T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/728—Bilirubin; including biliverdin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31942—Of aldehyde or ketone condensation product
    • Y10T428/31949—Next to cellulosic
    • Y10T428/31957—Wood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/103332—Bilirubin or uric acid standard or control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/106664—Blood serum or blood plasma standard or control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/146666—Bile pigment
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2525—Stabilizing or preserving

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electrotherapy Devices (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)

Abstract

EL OBJETO DE LA INVENCION ES UN SUERO ESTABLE DE CONTROL O CALIBRACION QUE CONTIENE BILIRRUBINA PARA LA COMPROBACION ANALITICA DE LA EXACTITUD DEL METODO RESPECTO A ALGUNOS PARAMETROS EN SUEROS DE PACIENTES. EL SUERO DE CONTROL O CALIBRACION CONFORME AL METODO SE UTILIZA PARA ESTABILIZAR LA BILIRRUBINA EN SOLUCIONES Y PARA AUMENTAR EN GENERAL LA ESTABILIDAD DE SUEROS DE CONTROL O CALIBRACION.
ES97104679T 1996-03-22 1997-03-19 Estabilizacion de bilirrubina en sueros de control y en calibradores. Expired - Lifetime ES2183999T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1996111458 DE19611458A1 (de) 1996-03-22 1996-03-22 Stabilisierung von Bilirubin in Kontrollseren und Kalibratoren
DE1996123955 DE19623955A1 (de) 1996-06-15 1996-06-15 Stabilisierung von Bilirubin in Kontrollseren und Kalibratoren

Publications (1)

Publication Number Publication Date
ES2183999T3 true ES2183999T3 (es) 2003-04-01

Family

ID=26024054

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97104679T Expired - Lifetime ES2183999T3 (es) 1996-03-22 1997-03-19 Estabilizacion de bilirrubina en sueros de control y en calibradores.

Country Status (6)

Country Link
US (1) US5854073A (es)
EP (1) EP0797098B1 (es)
JP (1) JP3165654B2 (es)
AT (1) ATE225515T1 (es)
DE (1) DE59708347D1 (es)
ES (1) ES2183999T3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696297B2 (en) * 2001-02-13 2004-02-24 Medical Analysis Systems, Inc. Non-oxidizable bilirubin substitutes and uses therefor
EP1794596B1 (en) * 2004-09-01 2013-11-06 Maine Standards Company LLC Novel stable lipid standards
CN100430091C (zh) * 2005-03-04 2008-11-05 江西特康科技有限公司 胆红素标准液及其制备方法和保存方法
DE102005043096A1 (de) 2005-09-10 2007-03-15 Kreyenborg Verwaltungen Und Beteiligungen Gmbh & Co. Kg Vorrichtung zum Filtrieren eines Fluids, insbesondere für kunststoffverarbeitende Anlagen
GB0526515D0 (en) * 2005-12-28 2006-02-08 Merck Sharp & Dohme Modulation of signalling pathways

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716060C3 (de) * 1977-04-09 1980-06-12 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilisierte Schnelldiagnostica mit Oxydationsindikatoren
US4288343A (en) * 1978-07-17 1981-09-08 Beckman Instruments, Inc. Method for increasing shelf-life of a serum bilirubin reference composition and composition produced thereby
US4250051A (en) * 1978-12-26 1981-02-10 Coulter Electronics, Inc. Preservative for use in calibrator compositions for blood analysis
US4344864A (en) * 1980-10-30 1982-08-17 Beckman Instruments, Inc. Method for increasing shelf-life of a serum conjugated bilirubin reference composition and composition produced thereby
DE3225331A1 (de) * 1982-07-07 1984-01-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur bestimmung von direktem und gesamt-bilirubin sowie hierfuer geeignetes reagens
JPS59125899A (ja) * 1982-12-29 1984-07-20 Nippon Shoji Kk 酵素法による直接ビリルビン測定用試薬および測定法
AU8874591A (en) * 1990-10-22 1992-05-20 Abbott Laboratories Stabilized anoxic diagnostic reagent solution
US5278073A (en) * 1991-05-08 1994-01-11 Streck Laboratories, Inc. Method of bilirubin assay
DE4135404A1 (de) * 1991-10-26 1993-04-29 Boehringer Mannheim Gmbh Stabiles fluessiges kontroll- bzw. eichserum fuer die klinische diagnostik
US5296377A (en) * 1992-12-15 1994-03-22 Boehringer Mannheim Corporation Control reagent containing a hydroxylamine or an antioxidant

Also Published As

Publication number Publication date
ATE225515T1 (de) 2002-10-15
JPH102901A (ja) 1998-01-06
DE59708347D1 (de) 2002-11-07
JP3165654B2 (ja) 2001-05-14
EP0797098A3 (de) 1998-10-14
EP0797098A2 (de) 1997-09-24
EP0797098B1 (de) 2002-10-02
US5854073A (en) 1998-12-29

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