ES2182541T3 - Pyrazolo(3,4-d)pirimidinas con actividad anticonvulsiva y antialergica /aniasmatica. - Google Patents

Pyrazolo(3,4-d)pirimidinas con actividad anticonvulsiva y antialergica /aniasmatica.

Info

Publication number
ES2182541T3
ES2182541T3 ES99929137T ES99929137T ES2182541T3 ES 2182541 T3 ES2182541 T3 ES 2182541T3 ES 99929137 T ES99929137 T ES 99929137T ES 99929137 T ES99929137 T ES 99929137T ES 2182541 T3 ES2182541 T3 ES 2182541T3
Authority
ES
Spain
Prior art keywords
energy
pyrazolo
aniasmatic
pyrimidins
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99929137T
Other languages
English (en)
Inventor
Thomas Arnold
Hans-Joachim Lankau
Manfred Menzer
Angelika Rostock
Christine Tober
Klaus Unverferth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AWD Pharma GmbH and Co KG
Original Assignee
Arzneimittelwerk Dresden GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arzneimittelwerk Dresden GmbH filed Critical Arzneimittelwerk Dresden GmbH
Application granted granted Critical
Publication of ES2182541T3 publication Critical patent/ES2182541T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Abstract

Nuevos compuestos de la Fórmula general 1 X o sus tautómeros, en los que significan X igual a oxígeno o azufre, e Y igual a halógeno, alquilo C1-C4, alcoxi C1-C4, trifluorometilo o trifluorometoxi m igual a un número de 0 a 5, exceptuando el compuesto 2-bencil-4, 5-dihidro-4-oxo-pirazolo[3, 4-d]pirimidina.
ES99929137T 1998-06-22 1999-06-04 Pyrazolo(3,4-d)pirimidinas con actividad anticonvulsiva y antialergica /aniasmatica. Expired - Lifetime ES2182541T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19827679A DE19827679A1 (de) 1998-06-22 1998-06-22 Adenosinrezeptoraffine, antikonvulsiv und antiallergisch/antiasthmatisch wirkende Pyrazolo[3,4-d]pyrimidine und Verfahren zu deren Herstellung
CZ2000594A CZ288195B6 (en) 1998-06-22 1999-06-04 Derivative of pyrazolo[3,4-d]pyrimidines exhibiting anticonvulsive a antiallergic/anti-asthmatic activity, process of its preparation and use
CA002297706A CA2297706A1 (en) 1998-06-22 2000-02-02 Anticonvulsive and antiallergic/anti-asthmatic pyrazolo-(3,4-d)pyrimidines having affinity for the adenosine receptor, and process for their preparation

Publications (1)

Publication Number Publication Date
ES2182541T3 true ES2182541T3 (es) 2003-03-01

Family

ID=27171156

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99929137T Expired - Lifetime ES2182541T3 (es) 1998-06-22 1999-06-04 Pyrazolo(3,4-d)pirimidinas con actividad anticonvulsiva y antialergica /aniasmatica.

Country Status (26)

Country Link
US (1) US6054460A (es)
EP (1) EP1005471B1 (es)
JP (1) JP2002518499A (es)
CN (1) CN1126753C (es)
AT (1) ATE223412T1 (es)
AU (1) AU748090B2 (es)
BG (1) BG104150A (es)
BR (1) BR9906552A (es)
CA (2) CA2301107A1 (es)
CZ (1) CZ288195B6 (es)
DE (2) DE19827679A1 (es)
DK (1) DK1005471T3 (es)
EA (1) EA002768B1 (es)
ES (1) ES2182541T3 (es)
HU (1) HUP0003783A3 (es)
IL (1) IL134439A0 (es)
NO (1) NO314760B1 (es)
NZ (1) NZ502880A (es)
PL (1) PL338897A1 (es)
PT (1) PT1005471E (es)
RU (1) RU2194050C2 (es)
SK (1) SK283506B6 (es)
TR (1) TR200000473T1 (es)
TW (1) TW449476B (es)
WO (1) WO1999067243A1 (es)
ZA (1) ZA200000742B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10042092A1 (de) * 2000-08-26 2002-03-07 Dresden Arzneimittel Antikonvulsiv wirkende 2,5-Dihydro-pyrazolo(3,4-d)pyrimidin-4-one und Verfahren zu deren Darstellung
WO2012125400A1 (en) * 2011-03-14 2012-09-20 Acorn Biomedical, Inc. Compositions and methods using adenosine a3 receptor antagonists for the treatment of inflammatory eye diseases
CN106749271B (zh) * 2016-12-07 2019-04-05 青岛科技大学 一类[1,2,4]-三氮唑并[1,5-a]嘧啶酮类杂环化合物、其制备方法及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988000192A1 (en) * 1986-06-26 1988-01-14 Warner-Lambert Company 5-SUBSTITUTED PYRAZOLO[4,3-d]PYRIMIDIN-7-ONES
DE19649460A1 (de) * 1996-11-26 1998-05-28 Bayer Ag Neue substituierte Pyrazolderivate

Also Published As

Publication number Publication date
PT1005471E (pt) 2003-01-31
NZ502880A (en) 2001-12-21
NO20000748L (no) 2000-04-07
WO1999067243A1 (de) 1999-12-29
JP2002518499A (ja) 2002-06-25
DE59902538D1 (de) 2002-10-10
CN1275128A (zh) 2000-11-29
SK2252000A3 (en) 2000-08-14
US6054460A (en) 2000-04-25
TR200000473T1 (tr) 2000-09-21
NO20000748D0 (no) 2000-02-15
DE19827679A1 (de) 1999-12-23
BR9906552A (pt) 2000-08-15
AU748090B2 (en) 2002-05-30
BG104150A (en) 2000-12-29
CZ2000594A3 (cs) 2000-10-11
DK1005471T3 (da) 2002-10-14
RU2194050C2 (ru) 2002-12-10
SK283506B6 (sk) 2003-08-05
EP1005471A1 (de) 2000-06-07
NO314760B1 (no) 2003-05-19
ZA200000742B (en) 2000-10-27
TW449476B (en) 2001-08-11
EP1005471B1 (de) 2002-09-04
HUP0003783A2 (hu) 2001-04-28
CZ288195B6 (en) 2001-05-16
PL338897A1 (en) 2000-11-20
AU4605499A (en) 2000-01-10
EA200000249A1 (ru) 2000-08-28
CA2297706A1 (en) 2001-08-02
IL134439A0 (en) 2001-04-30
CN1126753C (zh) 2003-11-05
CA2301107A1 (en) 1999-12-29
HUP0003783A3 (en) 2001-08-28
ATE223412T1 (de) 2002-09-15
EA002768B1 (ru) 2002-08-29

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