ES2181787T3 - Derivados de la 3h-2,3-benzodiazepina sustituidos en posicion 3, y su su utilizacion como medicamentos - Google Patents

Derivados de la 3h-2,3-benzodiazepina sustituidos en posicion 3, y su su utilizacion como medicamentos

Info

Publication number
ES2181787T3
ES2181787T3 ES95927636T ES95927636T ES2181787T3 ES 2181787 T3 ES2181787 T3 ES 2181787T3 ES 95927636 T ES95927636 T ES 95927636T ES 95927636 T ES95927636 T ES 95927636T ES 2181787 T3 ES2181787 T3 ES 2181787T3
Authority
ES
Spain
Prior art keywords
pct
substituted
derivatives
benzodiazepina
medications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95927636T
Other languages
English (en)
Inventor
Tamas Hamori
Istvan Tarnawa
Sandor Solyom
Pal Berzsenyi
Falglne Erzsebet Birkas
Ferenc Andrasi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2181787T3 publication Critical patent/ES2181787T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE DESCRIBEN NUEVOS DERIVADOS DE LA 3H-2,3-BENZODIAZEPINA SUSTITUIDOS EN POSICION 3 DE FORMULA GENERAL (I), EN LA QUE R{SUP,1}, R{SUP,2}, R{SUP,3}, R{SUP,4}, R{SUP,5}, R{SUP,6}, R{SUP,7} Y N TIENEN EL SIGNIFICADO DADO EN LA DESCRIPCION, SU OBTENCION Y SU UTILIZACION COMO MEDICAMENTOS.
ES95927636T 1994-08-01 1995-07-28 Derivados de la 3h-2,3-benzodiazepina sustituidos en posicion 3, y su su utilizacion como medicamentos Expired - Lifetime ES2181787T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4428835A DE4428835A1 (de) 1994-08-01 1994-08-01 Neue 3-substituierte 3H-2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ES2181787T3 true ES2181787T3 (es) 2003-03-01

Family

ID=6525693

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95927636T Expired - Lifetime ES2181787T3 (es) 1994-08-01 1995-07-28 Derivados de la 3h-2,3-benzodiazepina sustituidos en posicion 3, y su su utilizacion como medicamentos

Country Status (21)

Country Link
US (1) US5756495A (es)
EP (1) EP0775143B1 (es)
JP (1) JPH10504543A (es)
KR (1) KR100386709B1 (es)
CN (1) CN1048728C (es)
AT (1) ATE223415T1 (es)
AU (1) AU693241B2 (es)
CA (1) CA2195747C (es)
CZ (1) CZ291276B6 (es)
DE (2) DE4428835A1 (es)
DK (1) DK0775143T3 (es)
ES (1) ES2181787T3 (es)
FI (1) FI113177B (es)
HU (1) HU225500B1 (es)
MX (1) MX9700813A (es)
NO (1) NO319151B1 (es)
NZ (1) NZ290777A (es)
PT (1) PT775143E (es)
RU (1) RU2146678C1 (es)
SK (1) SK284103B6 (es)
WO (1) WO1996004283A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9701325A1 (hu) 1997-07-31 2000-08-28 Gyógyszerkutató Intézet Kft. Új 2,3-benzodiazepin-származékok
JP2001512731A (ja) * 1997-08-12 2001-08-28 エギシュ ヂョヂセルヂャール エルテー ＡＭＰＡ／Ｋａｉｎａｔｅ受容体阻害剤としての１，３−ジオキソロ／４，５−Ｈ／２，３／ベンゾジアゼピン誘導体
UA67749C2 (uk) 1997-08-12 2004-07-15 Егіш Дьйодьсердьяр Рт. Похідна 8-заміщеного-9н-1,3-діоксол/4,5-h//2,3/бензодіазепіну з властивостями амра/каїнатного антагоніста, спосіб одержання похідних, фармацевтична композиція (варіанти), спосіб її одержання та спосіб лікування
HU227128B1 (en) * 1999-07-07 2010-07-28 Egyt Gyogyszervegyeszeti Gyar New 2,3-benzodiazepine derivatives
NO320473B1 (no) * 2002-09-09 2005-12-12 Norsk Hydro As Anordning ved separator for separasjon av flerfasefluid.
US6858605B2 (en) 2003-02-04 2005-02-22 Ivax Drug Research Institute, Ltd. Substituted 2,3-benzodiazepine derivatives
GB0405034D0 (en) * 2004-03-05 2004-04-07 Novartis Ag Organic compounds
AU2006232517A1 (en) * 2005-04-04 2006-10-12 Eisai R&D Management Co., Ltd. Dihydropyridine compounds and compositions for headaches
DK2295049T3 (en) * 2005-09-09 2015-02-23 Novartis Ag Treatment of autoimmune diseases
WO2015121268A1 (de) * 2014-02-14 2015-08-20 Bayer Pharma Aktiengesellschaft 1-phenyl-3h-2,3-benzodiazepine und ihre verwendung als bromodomänen-inhibitoren

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU219778B (hu) * 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények

Also Published As

Publication number Publication date
MX9700813A (es) 1997-05-31
DE59510364D1 (de) 2002-10-10
JPH10504543A (ja) 1998-05-06
NO970435L (no) 1997-01-31
CN1155285A (zh) 1997-07-23
CA2195747C (en) 2006-01-24
WO1996004283A1 (de) 1996-02-15
FI970434A0 (fi) 1997-01-31
KR100386709B1 (ko) 2003-08-19
FI113177B (fi) 2004-03-15
NO970435D0 (no) 1997-01-31
PT775143E (pt) 2003-01-31
NO319151B1 (no) 2005-06-27
US5756495A (en) 1998-05-26
CA2195747A1 (en) 1996-02-15
CN1048728C (zh) 2000-01-26
HUT76801A (en) 1997-11-28
DK0775143T3 (da) 2002-12-02
HU225500B1 (en) 2007-01-29
CZ15997A3 (en) 1997-06-11
CZ291276B6 (cs) 2003-01-15
ATE223415T1 (de) 2002-09-15
FI970434A (fi) 1997-01-31
AU3160995A (en) 1996-03-04
EP0775143B1 (de) 2002-09-04
RU2146678C1 (ru) 2000-03-20
EP0775143A1 (de) 1997-05-28
SK13597A3 (en) 1997-07-09
AU693241B2 (en) 1998-06-25
NZ290777A (en) 1998-07-28
DE4428835A1 (de) 1996-02-08
SK284103B6 (sk) 2004-09-08

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