ES2180382A1 - Molecular diagnosis of the Gilbert syndrome consists of genomic DNA and allele based quantitative competitive amplification - Google Patents
Molecular diagnosis of the Gilbert syndrome consists of genomic DNA and allele based quantitative competitive amplificationInfo
- Publication number
- ES2180382A1 ES2180382A1 ES200001770A ES200001770A ES2180382A1 ES 2180382 A1 ES2180382 A1 ES 2180382A1 ES 200001770 A ES200001770 A ES 200001770A ES 200001770 A ES200001770 A ES 200001770A ES 2180382 A1 ES2180382 A1 ES 2180382A1
- Authority
- ES
- Spain
- Prior art keywords
- genomic dna
- molecular diagnosis
- quantitative competitive
- gilbert syndrome
- based quantitative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
The molecular diagnosis of the Gilbert syndrome comprises quantitative competitive amplification based on genomic DNA and three generators of a specific product of the allele with mutation and a non-specific product for the same region of the DNA. The laboratory technique increases practicability and economy.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200001770A ES2180382B2 (en) | 2000-07-17 | 2000-07-17 | METHOD OF DETECTION OF A MUTATION IN THE PROMOTER OF THE GENE OF UDP-GLUCURONOSIL TRANSFERASE BILIRRUBINE, ASSOCIATED WITH THE GILBERT SYNDROME. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200001770A ES2180382B2 (en) | 2000-07-17 | 2000-07-17 | METHOD OF DETECTION OF A MUTATION IN THE PROMOTER OF THE GENE OF UDP-GLUCURONOSIL TRANSFERASE BILIRRUBINE, ASSOCIATED WITH THE GILBERT SYNDROME. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2180382A1 true ES2180382A1 (en) | 2003-02-01 |
ES2180382B2 ES2180382B2 (en) | 2004-08-01 |
Family
ID=8494293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200001770A Expired - Fee Related ES2180382B2 (en) | 2000-07-17 | 2000-07-17 | METHOD OF DETECTION OF A MUTATION IN THE PROMOTER OF THE GENE OF UDP-GLUCURONOSIL TRANSFERASE BILIRRUBINE, ASSOCIATED WITH THE GILBERT SYNDROME. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2180382B2 (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2668162A1 (en) * | 1990-10-17 | 1992-04-24 | Eurobio Lab | PCR probes specific for delta-F-508 mucoviscidosis mutated gene - and normal allele, useful for detection of heterozygous mucoviscidosis mutation carriers |
US5972602A (en) * | 1993-08-27 | 1999-10-26 | Australian Red Cross Society | Quantitative PCR-based method of gene detection |
-
2000
- 2000-07-17 ES ES200001770A patent/ES2180382B2/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2668162A1 (en) * | 1990-10-17 | 1992-04-24 | Eurobio Lab | PCR probes specific for delta-F-508 mucoviscidosis mutated gene - and normal allele, useful for detection of heterozygous mucoviscidosis mutation carriers |
US5972602A (en) * | 1993-08-27 | 1999-10-26 | Australian Red Cross Society | Quantitative PCR-based method of gene detection |
Non-Patent Citations (2)
Title |
---|
G_RTLER, V. et al. "Use of double gradient donaturing gradient gel electrophoresis to detect (AT)n polymorphisms in the UDP-glucuronosyltransferase 1 gene promoter associated with Gilbert's syndrome", ELECTROPHORESIS, 1999, Vol. 20, pßginas 2841-2843. Todo el documento. * |
MONAGHAM, G. et al. "Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome", THE LANCET, 1996, Vol. 347, pßginas 578-581. Todo el documento. * |
Also Published As
Publication number | Publication date |
---|---|
ES2180382B2 (en) | 2004-08-01 |
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