ES2179180T3 - Procedimiento para la recuperacion de ampicilina. - Google Patents
Procedimiento para la recuperacion de ampicilina.Info
- Publication number
- ES2179180T3 ES2179180T3 ES96906103T ES96906103T ES2179180T3 ES 2179180 T3 ES2179180 T3 ES 2179180T3 ES 96906103 T ES96906103 T ES 96906103T ES 96906103 T ES96906103 T ES 96906103T ES 2179180 T3 ES2179180 T3 ES 2179180T3
- Authority
- ES
- Spain
- Prior art keywords
- ampicillin
- apa
- recovery
- recovered
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/04—Preparation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
- C12P37/04—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by acylation of the substituent in the 6 position
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Manufacturing Of Electric Cables (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Mechanical Coupling Of Light Guides (AREA)
- Ticket-Dispensing Machines (AREA)
- Bipolar Transistors (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
Abstract
PROCESO DE RECUPERACION DE LA AMPICILINA EN UNA MEZCLA QUE CONTENGA AMPICILINA Y ACIDO 6 AMINOPENICILICO (6 APA), CONSISTENTE EN SOMETER UNA MEZCLA DE AMPICILINA Y 6 APA, A UN PH SUPERIOR A 7, QUE, APARTE DE CUALQUIER RESTO SOLIDO DE AMPICILINA QUE ESTE PRESENTE, ES HOMOGENEA A UN PH ENTRE 7 Y 8,5, A UNA DISMINUCION DE PH HASTA QUE SE ALCANCE UN PH INFERIOR A 8,2, Y SE RECUPERE LA SUSTANCIA SOLIDA PRESENTE. EL PROCESO ES ADECUADO, EN PARTICULAR, PARA SER APLICADO A LA MEZCLA REACTIVA OBTENIDA DESPUES DE LA REACCION ENZIMATICA DE ACILACION DEL 6 APA CON UN DERIVADO DE LA FENILGLICIDINA COMO AGENTE DE ACILACION. EN CONSECUENCIA, PUEDE RECUPERARSE LA AMPICILINA PURA DE UN MODO SIMPLE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE9500291A BE1009264A3 (nl) | 1995-03-31 | 1995-03-31 | Werkwijze voor de winning van ampicilline. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2179180T3 true ES2179180T3 (es) | 2003-01-16 |
Family
ID=3888891
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96906103T Expired - Lifetime ES2179180T3 (es) | 1995-03-31 | 1996-03-25 | Procedimiento para la recuperacion de ampicilina. |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0869960B1 (es) |
JP (1) | JPH11502832A (es) |
KR (1) | KR100442040B1 (es) |
CN (1) | CN1103777C (es) |
AT (1) | ATE220069T1 (es) |
AU (1) | AU4958296A (es) |
BE (1) | BE1009264A3 (es) |
CZ (1) | CZ307497A3 (es) |
DE (1) | DE69622193T2 (es) |
ES (1) | ES2179180T3 (es) |
IN (1) | IN183010B (es) |
MX (1) | MX9707550A (es) |
WO (1) | WO1996030376A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL1006266C2 (nl) * | 1997-06-10 | 1998-12-14 | Chemferm Vof | Werkwijze voor de bereiding van ampicilline. |
NL1007076C2 (nl) * | 1997-09-19 | 1999-03-22 | Dsm Nv | Werkwijze voor de winning van een ß-lactam antibioticum. |
NL1007077C2 (nl) * | 1997-09-19 | 1999-03-22 | Dsm Nv | Werkwijze voor de winning van een ß-lactam antibioticum. |
PE20000879A1 (es) * | 1998-04-29 | 2000-09-23 | Dsm Nv | METODO PARA CRISTALIZAR UN ANTIBIOTICO ß-LACTAMICO |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1178434B (de) * | 1962-09-04 | 1964-09-24 | Bayer Ag | Verfahren zur Trennung von 6-Aminopenicillan-saeure und ª‡-Aminobenzylpenicillin |
FR2188608A5 (en) * | 1972-06-14 | 1974-01-18 | Aries Robert | Penicillins prepn by acylating 6-apa - in presence of catalytic enzymes using free acids |
US3980637A (en) * | 1975-03-17 | 1976-09-14 | Bristol-Myers Company | Production of amoxicillin |
US4354971A (en) * | 1981-06-22 | 1982-10-19 | Eli Lilly And Company | Non-extractive penicillin V recovery process |
BE1007296A3 (nl) * | 1993-07-19 | 1995-05-09 | Dsm Nv | Werkwijze voor de bereiding van een beta-lactamderivaat. |
-
1995
- 1995-03-31 BE BE9500291A patent/BE1009264A3/nl not_active IP Right Cessation
-
1996
- 1996-03-25 AU AU49582/96A patent/AU4958296A/en not_active Abandoned
- 1996-03-25 DE DE69622193T patent/DE69622193T2/de not_active Expired - Fee Related
- 1996-03-25 CN CN96194145A patent/CN1103777C/zh not_active Expired - Fee Related
- 1996-03-25 AT AT96906103T patent/ATE220069T1/de not_active IP Right Cessation
- 1996-03-25 KR KR1019970707021A patent/KR100442040B1/ko not_active IP Right Cessation
- 1996-03-25 EP EP96906103A patent/EP0869960B1/en not_active Expired - Lifetime
- 1996-03-25 MX MX9707550A patent/MX9707550A/es not_active IP Right Cessation
- 1996-03-25 WO PCT/NL1996/000128 patent/WO1996030376A1/en active IP Right Grant
- 1996-03-25 CZ CZ973074A patent/CZ307497A3/cs unknown
- 1996-03-25 ES ES96906103T patent/ES2179180T3/es not_active Expired - Lifetime
- 1996-03-25 JP JP8529208A patent/JPH11502832A/ja active Pending
- 1996-03-26 IN IN483MA1996 patent/IN183010B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP0869960B1 (en) | 2002-07-03 |
KR100442040B1 (ko) | 2005-08-05 |
BE1009264A3 (nl) | 1997-01-07 |
ATE220069T1 (de) | 2002-07-15 |
DE69622193D1 (de) | 2002-08-08 |
MX9707550A (es) | 1997-11-29 |
KR19980703622A (ko) | 1998-12-05 |
JPH11502832A (ja) | 1999-03-09 |
EP0869960A1 (en) | 1998-10-14 |
CN1103777C (zh) | 2003-03-26 |
IN183010B (es) | 1999-08-21 |
CZ307497A3 (cs) | 1998-01-14 |
DE69622193T2 (de) | 2003-03-20 |
CN1185157A (zh) | 1998-06-17 |
AU4958296A (en) | 1996-10-16 |
WO1996030376A1 (en) | 1996-10-03 |
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