ES2171952T3 - Acidos quinoloncarboxilicos 7-(3-vinil-1,4-piperazin-1-il)-substituidos. - Google Patents

Acidos quinoloncarboxilicos 7-(3-vinil-1,4-piperazin-1-il)-substituidos.

Info

Publication number
ES2171952T3
ES2171952T3 ES97928208T ES97928208T ES2171952T3 ES 2171952 T3 ES2171952 T3 ES 2171952T3 ES 97928208 T ES97928208 T ES 97928208T ES 97928208 T ES97928208 T ES 97928208T ES 2171952 T3 ES2171952 T3 ES 2171952T3
Authority
ES
Spain
Prior art keywords
stands
hydrogen
carbon atoms
methyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97928208T
Other languages
English (en)
Inventor
Thomas Himmler
Thomas Jaetsch
Werner Hallenbach
Hans-Georg Rast
Heinz-Georg Wetzstein
Ernst Heinen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19651687A external-priority patent/DE19651687A1/de
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2171952T3 publication Critical patent/ES2171952T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA INVENCION TRATA DE NUEVOS ACIDOS QUINOLONACARBOXILO SUSTITUIDOS POR 7 - (3 - VINIL - 1,4 - PIPERACIN - 1 - ILO) DE FORMULA GENERAL (I) EN LA CUAL R 1 ES HIDROGENO, ALQUILO C ON 1 A 4 ATOMOS DE CARBONO OPCIONALMENTE SUSTITUIDO POR HIDROXI, METOXI, AMINO, METILAMINO O DIMETILAMINO, O (5 METIL - 2 OXO - 1,3 - HIDROXOL - 4 - ILO) - METILO, R 2 ES HIDROGENO O FLUOR, SI SIMULTANEAMENTE R 4 ES DIFERENTE DE HIDROGENO O FLUOR Y PUEDE SER AMINO, METILO O VINILO, R 3 ES HIDROGENO, BENZILO, ALQUILO CON 1 A 3 ATOMOS DE CARBONO, RADICALES DE ESTRUCTURA - CH = CH - COOR 5 , CH 2 CH 2 - COOR 5 , - CH 2 CH 2 CN, CH 2 CH 2 COOCH SUB ,3 , - CH 2 COCH 3 , EN LAS CUALES R 5 ES METILO O ETILO, O UN RADICAL DE ESTRUCTURA GENERAL R 6 - (NH - CHR 7 - CO) N -, EN LA QUE R 6 ES HIDROGENO, ALQ UILO CON 1 A 3 ATOMOS DE CARBONO O EL RADICAL - COO - TERT. BUTILO, R 7 ES HIDROGENO, ALQUILO CON 1 A 4 ATOMOS DE CAR BONO, HIDROXIALQUILO CON 1 O 2 ATOMOS DE CARBONO, CH 2 FENILO, AMINOALQUILO O TIOALQUILO CON 1 O 2 ATOMOS DE CARBONO, Y N = 1 O 2, Y R 4 ES HIDROGENO O FLUOR, SI R 2 ES AMINO, METILO O VINILO, O ES CLORO, METOXI, DIFLUOROMETOXI, CN O ETINILO; PROCEDIMIENTO PARA SU UTILIZACION Y UTILIZACION EN AGENTES BACTERICIDAS.
ES97928208T 1996-06-28 1997-06-16 Acidos quinoloncarboxilicos 7-(3-vinil-1,4-piperazin-1-il)-substituidos. Expired - Lifetime ES2171952T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19625988 1996-06-28
DE19651687A DE19651687A1 (de) 1996-06-28 1996-12-12 7-(3-Vinyl-1,4-piperazin-1-yl)-substituierte Chinoloncarbonsäuren

Publications (1)

Publication Number Publication Date
ES2171952T3 true ES2171952T3 (es) 2002-09-16

Family

ID=26027015

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97928208T Expired - Lifetime ES2171952T3 (es) 1996-06-28 1997-06-16 Acidos quinoloncarboxilicos 7-(3-vinil-1,4-piperazin-1-il)-substituidos.

Country Status (10)

Country Link
EP (1) EP0907648B1 (es)
JP (1) JP2000513368A (es)
AT (1) ATE214060T1 (es)
AU (1) AU720322B2 (es)
BR (1) BR9710005A (es)
CA (1) CA2259217A1 (es)
ES (1) ES2171952T3 (es)
NZ (1) NZ333578A (es)
TW (1) TW415943B (es)
WO (1) WO1998000421A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10337191A1 (de) * 2003-08-13 2005-03-17 Bayer Healthcare Ag Neue Verwendung von Chinolon-Antibiotika

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0230053A3 (en) * 1986-01-17 1988-03-30 American Cyanamid Company 7-(substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids

Also Published As

Publication number Publication date
EP0907648B1 (de) 2002-03-06
NZ333578A (en) 2000-08-25
TW415943B (en) 2000-12-21
AU3259197A (en) 1998-01-21
AU720322B2 (en) 2000-05-25
JP2000513368A (ja) 2000-10-10
BR9710005A (pt) 1999-08-10
WO1998000421A1 (de) 1998-01-08
EP0907648A1 (de) 1999-04-14
CA2259217A1 (en) 1998-01-08
ATE214060T1 (de) 2002-03-15

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