ES2170195T3 - Peptidos del virus de epstein-barr y anticuerpos contra estos peptidos. - Google Patents

Peptidos del virus de epstein-barr y anticuerpos contra estos peptidos.

Info

Publication number
ES2170195T3
ES2170195T3 ES96201457T ES96201457T ES2170195T3 ES 2170195 T3 ES2170195 T3 ES 2170195T3 ES 96201457 T ES96201457 T ES 96201457T ES 96201457 T ES96201457 T ES 96201457T ES 2170195 T3 ES2170195 T3 ES 2170195T3
Authority
ES
Spain
Prior art keywords
peptides
ebv
epstein
barr virus
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96201457T
Other languages
English (en)
Inventor
Jaap Michiel Middeldorp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux BV
Original Assignee
Organon Teknika BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Teknika BV filed Critical Organon Teknika BV
Application granted granted Critical
Publication of ES2170195T3 publication Critical patent/ES2170195T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/811—Peptides or proteins is immobilized on, or in, an inorganic carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

LA INVENCION SE REFIERE A PEPTIDOS O FRAGMENTOS DE LOS MISMOS QUE SON INMUNOQUIMICAMENTE REACTIVOS CON LOS ANTICUERPOS DEL VIRUS EPSTEIN-BARR (VEB).NUEVOS ANTICUERPOS DIRIGIDOS A DICHOS PEPTIDOS O FRAGMENTOS DE LOS MISMOS SON TAMBIEN PARTE DE LA INVENCION.LA INVENCION TAMBIEN SE REFIERE A UN METODO PARA LA DETECCION DE VEB O ANTICUERPOS DIRIGIDOS CONTRA VEB EN UN FLUIDO A Y TAMBIEN A UN REACTIVO INMUNOQUIMICO QUE COMPRENDE UN PEPTIDO, UN FRAGMENTO O UN POLIPEPTIDO SEGUN LA INVENCION Y UN EQUIPO DE PRUEBA PARA SER USADO CUANDO SE APLICAN DICHOS METODOS DE DETECCION. LA DETECCION DEL VEB EN UN FLUIDO DE PRUEBA O EN UNA MUESTRA DE TEJIDO USANDO ANTICUERPOS, MONOCLONALES Y POLICLONALES, DIRIGIDOS A DICHO PEPTIDO, QUE TIENEN LAS CARACTERISTICAS PARA LA DETECCION DE UNA PROTEINA NATIVA Y DESNATURALIZADA VEB-EA ES TAMBIEN PARTE DE DICHA INVENCION.
ES96201457T 1995-06-06 1996-05-28 Peptidos del virus de epstein-barr y anticuerpos contra estos peptidos. Expired - Lifetime ES2170195T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95201486 1995-06-06

Publications (1)

Publication Number Publication Date
ES2170195T3 true ES2170195T3 (es) 2002-08-01

Family

ID=8220358

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96201457T Expired - Lifetime ES2170195T3 (es) 1995-06-06 1996-05-28 Peptidos del virus de epstein-barr y anticuerpos contra estos peptidos.

Country Status (13)

Country Link
US (2) US5843405A (es)
EP (1) EP0747481B1 (es)
JP (2) JP4319703B2 (es)
KR (1) KR100523972B1 (es)
AT (1) ATE211172T1 (es)
AU (1) AU707301B2 (es)
CA (1) CA2178057C (es)
DE (1) DE69618080T2 (es)
DK (1) DK0747481T3 (es)
ES (1) ES2170195T3 (es)
HK (1) HK1001164A1 (es)
PT (1) PT747481E (es)
ZA (1) ZA964683B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2824912B1 (fr) * 2001-05-18 2004-10-29 Jacques Gregoire Dispositif de kit elisa, base sur un antigene : proteines m dbp, du virus ebv, particulierement destine au diagnostic serologique du cancer npc, et le procede de preparation de cette proteine
JP2005060314A (ja) * 2003-08-13 2005-03-10 Masao Tanihara 化粧料
MX2007005891A (es) 2004-11-15 2007-11-23 Johnson & Johnson Cateter con detector de temperatura microfabricado.
EP2101177A1 (en) * 2008-03-10 2009-09-16 Universite Joseph Fourier Use of synthetic peptide derived from zebra protein for the in vitro diagnosis of the epstein-barr virus (EBV) reactivation
GB201121308D0 (en) 2011-12-12 2012-01-25 Cell Medica Ltd Process
US10351824B2 (en) 2011-12-12 2019-07-16 Cell Medica Limited Process of expanding T cells
ES2748652T3 (es) 2012-02-09 2020-03-17 Baylor College Medicine Mezclas pep para generar CTL multivíricos con amplia especificidad
JP6999941B2 (ja) 2015-09-18 2022-02-10 ベイラー カレッジ オブ メディスン 病原体からの免疫原性抗原同定および臨床的有効性との相関
US10772914B1 (en) * 2019-04-18 2020-09-15 Baylor College Of Medicine EBV-specific immune cells
CN111574621B (zh) * 2020-04-30 2022-03-29 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 一种中和eb病毒的单克隆抗体及其应用
CN111690056B (zh) * 2020-04-30 2021-12-21 清华大学 一种中和eb病毒的单克隆抗体及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61257188A (ja) * 1984-08-23 1986-11-14 ハンス　ヨツト　ヴオルフ Ｅｂｖゲノムのｄｎａ配列、組換えｄｎａ分子、ならびにｅｂｖ関連抗原および該抗原を含有する診断用組成物および製剤組成物の製造法
DE3583564D1 (de) * 1984-08-23 1991-08-29 Hans Joachim Wolf Dna-sequenzen des ebv-genoms, rekombinante dna-molekuele, verfahren zur herstellung von ebv-verwandten antigenen sowie diagnostische zusammensetzungen und pharmazeutische zusammensetzungen, die die genannten antigene enthalten.
US5256768A (en) * 1985-12-13 1993-10-26 The Johns Hopkins University Expression of antigenic Epstein-Barr virus polypeptides in bacteria and their use in diagnostics
US4761470A (en) * 1985-12-16 1988-08-02 Merck & Co., Inc. Immunogenic synthetic peptide capable of eliciting herpes simplex virus neutralizing antibody
US5087557A (en) * 1986-06-23 1992-02-11 Genetic Systems Corporation Human monoclonal antibody to lymphadenopathy-associated virus
US4879213A (en) * 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse

Also Published As

Publication number Publication date
US5843405A (en) 1998-12-01
EP0747481A1 (en) 1996-12-11
AU707301B2 (en) 1999-07-08
DE69618080T2 (de) 2002-06-13
CA2178057C (en) 2010-08-03
AU5479396A (en) 1996-12-19
EP0747481B1 (en) 2001-12-19
JP2008188017A (ja) 2008-08-21
US6143865A (en) 2000-11-07
HK1001164A1 (en) 1998-05-29
KR100523972B1 (ko) 2006-04-14
CA2178057A1 (en) 1996-12-07
JP4319703B2 (ja) 2009-08-26
PT747481E (pt) 2002-05-31
JP4612071B2 (ja) 2011-01-12
ZA964683B (en) 1997-01-07
DK0747481T3 (da) 2002-04-08
JPH0925295A (ja) 1997-01-28
ATE211172T1 (de) 2002-01-15
DE69618080D1 (de) 2002-01-31

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