ES2167014T3 - Procedimiento de preparacion de agentes de contraste. - Google Patents

Procedimiento de preparacion de agentes de contraste.

Info

Publication number: ES2167014T3
Authority: ES; Spain
Prior art keywords: preparation procedure; contrast agent; agent preparation; acid; acilation
Prior art date: 1996-08-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

ES97937743T

Other languages

English (en)

Spanish (es)

Inventor

Trygve Gulbrandsen

Odd Einar Ingvoldstad

Lars Terje Holmaas

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

GE Healthcare AS

Original Assignee

Nycomed Imaging AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-29

Filing date

1997-08-29

Publication date

2002-05-01

1997-08-29 Application filed by Nycomed Imaging AS filed Critical Nycomed Imaging AS

2002-05-01 Application granted granted Critical

2002-05-01 Publication of ES2167014T3 publication Critical patent/ES2167014T3/es

2017-08-29 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 2
239000002872 contrast media Substances 0.000 title 1
239000002253 acid Substances 0.000 abstract 3
-1 CARBOXYL Chemical class 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
239000007795 chemical reaction product Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Steroid Compounds (AREA)
Glass Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Iron Core Of Rotating Electric Machines (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Exposure Of Semiconductors, Excluding Electron Or Ion Beam Exposure (AREA)
Hydrogenated Pyridines (AREA)

ES97937743T 1996-08-29 1997-08-29 Procedimiento de preparacion de agentes de contraste. Expired - Lifetime ES2167014T3 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9618055.9A GB9618055D0 (en)	1996-08-29	1996-08-29	Process

Publications (1)

Publication Number	Publication Date
ES2167014T3 true ES2167014T3 (es)	2002-05-01

Family

ID=10799119

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES97937743T Expired - Lifetime ES2167014T3 (es)	1996-08-29	1997-08-29	Procedimiento de preparacion de agentes de contraste.

Country Status (21)

Country	Link
EP (1)	EP0923537B1 (de)
JP (1)	JP4113587B2 (de)
KR (1)	KR100539647B1 (de)
CN (1)	CN1092182C (de)
AT (1)	ATE207880T1 (de)
AU (1)	AU717842B2 (de)
BG (1)	BG103288A (de)
BR (1)	BR9711358A (de)
CA (1)	CA2263426A1 (de)
CZ (1)	CZ296230B6 (de)
DE (1)	DE69707901T2 (de)
EE (1)	EE9900081A (de)
ES (1)	ES2167014T3 (de)
GB (1)	GB9618055D0 (de)
HU (1)	HUP9903852A3 (de)
IL (1)	IL128685A0 (de)
NO (1)	NO322141B1 (de)
NZ (1)	NZ334818A (de)
PL (1)	PL193698B1 (de)
SK (1)	SK26399A3 (de)
WO (1)	WO1998008805A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9618056D0 (en) *	1996-08-29	1996-10-09	Nycomed Imaging As	Process
GB9903109D0 (en)	1999-02-11	1999-04-07	Nycomed Imaging As	Process
ITMI20010773A1 (it) *	2001-04-11	2002-10-11	Chemi Spa	Processo per la produzione di ioexolo ad elevata purezza
CN100344606C (zh) *	2005-12-28	2007-10-24	江苏省原子医学研究所	一种碘昔兰的制备方法
US20110021822A1 (en) *	2009-07-21	2011-01-27	Ge Healthcare As	continuous deacetylation and purification process in synthesis of non-ionic x-ray contrast agents
CN103058880B (zh) *	2011-10-21	2015-08-05	连云港润众制药有限公司	碘克沙醇及其合成中间体的制备方法
ES2683143T3 (es)	2013-12-06	2018-09-25	Ge Healthcare As	Proceso alternativo para la purificación de un intermedio en la síntesis de agentes de contraste de rayos X no iónicos
WO2015082718A1 (en) *	2013-12-06	2015-06-11	Ge Healthcare As	Alternative process for the purification of an intermediate in the synthesis of non-ionic x-ray contrast agents
CN104356023B (zh) *	2014-10-29	2016-04-13	武汉工程大学	一种碘曲仑的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2132530B1 (de) *	1971-04-07	1974-08-02	Guerbet Lab Andre
GB1548594A (en) *	1976-06-11	1979-07-18	Nyegaard & Co As	Triiodoisophthalic acid amides
EP0105752B1 (de) *	1982-10-01	1986-05-07	NYEGAARD & CO. A/S	Röntgenkontrastmittel
US4584401A (en) *	1983-10-20	1986-04-22	Biophysica Foundation	Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
WO1987000757A1 (en) *	1985-08-09	1987-02-12	Cook Imaging, Inc.	Non-ionic polyol contrast media from ionic contrast media

1996
- 1996-08-29 GB GBGB9618055.9A patent/GB9618055D0/en active Pending
1997
- 1997-08-29 EP EP97937743A patent/EP0923537B1/de not_active Expired - Lifetime
- 1997-08-29 BR BR9711358A patent/BR9711358A/pt not_active Application Discontinuation
- 1997-08-29 CN CN97197523A patent/CN1092182C/zh not_active Expired - Lifetime
- 1997-08-29 DE DE69707901T patent/DE69707901T2/de not_active Expired - Lifetime
- 1997-08-29 CZ CZ0067099A patent/CZ296230B6/cs not_active IP Right Cessation
- 1997-08-29 EE EEP199900081A patent/EE9900081A/xx unknown
- 1997-08-29 ES ES97937743T patent/ES2167014T3/es not_active Expired - Lifetime
- 1997-08-29 SK SK263-99A patent/SK26399A3/sk unknown
- 1997-08-29 KR KR10-1999-7001685A patent/KR100539647B1/ko active IP Right Grant
- 1997-08-29 HU HU9903852A patent/HUP9903852A3/hu unknown
- 1997-08-29 JP JP51140198A patent/JP4113587B2/ja not_active Expired - Lifetime
- 1997-08-29 AT AT97937743T patent/ATE207880T1/de not_active IP Right Cessation
- 1997-08-29 IL IL12868597A patent/IL128685A0/xx unknown
- 1997-08-29 WO PCT/GB1997/002335 patent/WO1998008805A1/en active IP Right Grant
- 1997-08-29 NZ NZ334818A patent/NZ334818A/xx unknown
- 1997-08-29 PL PL97331821A patent/PL193698B1/pl unknown
- 1997-08-29 CA CA002263426A patent/CA2263426A1/en not_active Abandoned
- 1997-08-29 AU AU40267/97A patent/AU717842B2/en not_active Ceased
1999
- 1999-02-25 NO NO19990890A patent/NO322141B1/no not_active IP Right Cessation
- 1999-03-26 BG BG103288A patent/BG103288A/xx unknown

Also Published As

Publication number	Publication date
EE9900081A (et)	1999-10-15
KR100539647B1 (ko)	2005-12-29
NZ334818A (en)	2000-08-25
JP4113587B2 (ja)	2008-07-09
IL128685A0 (en)	2000-01-31
DE69707901D1 (de)	2001-12-06
SK26399A3 (en)	2000-03-13
ATE207880T1 (de)	2001-11-15
BR9711358A (pt)	1999-08-17
PL193698B1 (pl)	2007-03-30
NO322141B1 (no)	2006-08-21
NO990890D0 (no)	1999-02-25
GB9618055D0 (en)	1996-10-09
CN1092182C (zh)	2002-10-09
PL331821A1 (en)	1999-08-02
CZ296230B6 (cs)	2006-02-15
CN1228762A (zh)	1999-09-15
HUP9903852A3 (en)	2001-08-28
JP2000517313A (ja)	2000-12-26
DE69707901T2 (de)	2002-07-18
EP0923537A1 (de)	1999-06-23
CA2263426A1 (en)	1998-03-05
CZ67099A3 (cs)	1999-08-11
KR20000035944A (ko)	2000-06-26
WO1998008805A1 (en)	1998-03-05
BG103288A (en)	2000-01-31
AU717842B2 (en)	2000-04-06
NO990890L (no)	1999-02-25
EP0923537B1 (de)	2001-10-31
HUP9903852A2 (hu)	2000-03-28
AU4026797A (en)	1998-03-19

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