ES2160871T3 - Procedimiento de preparacion del hidrocloruro de paroxetina amorfo. - Google Patents

Procedimiento de preparacion del hidrocloruro de paroxetina amorfo.

Info

Publication number
ES2160871T3
ES2160871T3 ES97108713T ES97108713T ES2160871T3 ES 2160871 T3 ES2160871 T3 ES 2160871T3 ES 97108713 T ES97108713 T ES 97108713T ES 97108713 T ES97108713 T ES 97108713T ES 2160871 T3 ES2160871 T3 ES 2160871T3
Authority
ES
Spain
Prior art keywords
paroxetine
amorfo
hydrocloride
preparation procedure
paroxetine hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97108713T
Other languages
English (en)
Inventor
Shu-Zhong Wang
Takashi Okazoe
Yasushi Matsumura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGC Inc
Original Assignee
Asahi Glass Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Glass Co Ltd filed Critical Asahi Glass Co Ltd
Application granted granted Critical
Publication of ES2160871T3 publication Critical patent/ES2160871T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN METODO DE PRODUCCION DE CLORHIDRATO DE PAROXETINA AMORFO, QUE CONSISTE EN CONVERTIR PAROXETINA O SU SAL DE ACIDO ALCANOICO INFERIOR, EN CLORHIDRATO DE PAROXETINA Y, A CONTINUACION, DESHIDRATAR POR PULVERIZACION UNA SOLUCION DE DICHO CLORHIDRATO.
ES97108713T 1996-05-30 1997-05-30 Procedimiento de preparacion del hidrocloruro de paroxetina amorfo. Expired - Lifetime ES2160871T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13719296 1996-05-30

Publications (1)

Publication Number Publication Date
ES2160871T3 true ES2160871T3 (es) 2001-11-16

Family

ID=15192956

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97108713T Expired - Lifetime ES2160871T3 (es) 1996-05-30 1997-05-30 Procedimiento de preparacion del hidrocloruro de paroxetina amorfo.

Country Status (6)

Country Link
US (2) US20010021776A1 (es)
EP (2) EP1090918A1 (es)
AT (1) ATE203749T1 (es)
CA (1) CA2206592A1 (es)
DE (1) DE69705896T2 (es)
ES (1) ES2160871T3 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6638948B1 (en) * 1996-09-09 2003-10-28 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
CA2193939C (en) * 1996-12-24 2002-02-12 K.S. Keshava Murthy Useful form of anhydrous paroxetine hydrochloride
EA002034B1 (ru) * 1997-01-15 2001-12-24 Смитклайн Бичам Плс Композиция на основе пароксетина
KR100543614B1 (ko) 1997-06-10 2006-01-20 신톤 비.브이. 4-페닐피페리딘 화합물
CA2319652A1 (en) * 1998-02-06 1999-08-12 Michael Urquhart Salts of paroxetine
GB9806312D0 (en) * 1998-03-24 1998-05-20 Smithkline Beecham Plc Novel formulations
US6168805B1 (en) * 1998-05-07 2001-01-02 Endo Pharmaceuticals, Inc. Aqueous process for manufacturing paroxetine solid dispersions
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
GB9814316D0 (en) * 1998-07-02 1998-09-02 Smithkline Beecham Plc Novel compounds
ES2138937B1 (es) 1998-07-07 2000-10-01 Medichem Sa Polimorfo de maleato de paroxetina y formulaciones farmaceuticas que lo contienen.
EP1102764A1 (en) * 1998-08-08 2001-05-30 Smithkline Beecham Plc Paroxetine salts
GB9824298D0 (en) * 1998-11-05 1998-12-30 Smithkline Beecham Plc Novel process
GB9826180D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
IN191492B (es) * 1999-05-25 2003-12-06 Ranbaxy Lab Ltd
GB9914600D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel,process
ES2206254T3 (es) 1999-07-01 2004-05-16 Italfarmaco S.P.A. Complejos de paroxetina con ciclodextrinas o derivados de ciclodextrinas.
HU226912B1 (en) * 2000-04-07 2010-03-01 Richter Gedeon Nyrt New paroxetin salt and medicament containing it
JPWO2002022609A1 (ja) * 2000-09-14 2004-01-22 旭硝子株式会社 実質的に有機溶媒を含まないパロキセチン塩類の製造方法
US20030032809A1 (en) * 2001-04-25 2003-02-13 Subhash P. Upadhyaya Optimized procedures for the manufacture of paroxetine salts
IL159280A0 (en) * 2001-06-14 2004-06-01 Teva Pharma A process for preparing paroxetine hcl which limits formation of pink colored compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
EP0542355A1 (en) * 1991-11-15 1993-05-19 Merck Frosst Canada Inc. Amorphous (Quinolin-2-ylmethoxy)indoles as leukotriene antagonists
IT1274241B (it) * 1993-12-03 1997-07-15 Smithkline Beecham Farma Complessi agente terapeutico/matrice polimerica dotati di migliorate caratteristiche di sapore e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
ATE203749T1 (de) 2001-08-15
US20030181725A1 (en) 2003-09-25
EP0810224B1 (en) 2001-08-01
US20010021776A1 (en) 2001-09-13
EP0810224A1 (en) 1997-12-03
EP1090918A1 (en) 2001-04-11
CA2206592A1 (en) 1997-11-30
DE69705896T2 (de) 2002-04-11
DE69705896D1 (de) 2001-09-06

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