ES2056381T3 - Preparacion de intermedios diazabiciclos. - Google Patents
Preparacion de intermedios diazabiciclos.Info
- Publication number
- ES2056381T3 ES2056381T3 ES90304442T ES90304442T ES2056381T3 ES 2056381 T3 ES2056381 T3 ES 2056381T3 ES 90304442 T ES90304442 T ES 90304442T ES 90304442 T ES90304442 T ES 90304442T ES 2056381 T3 ES2056381 T3 ES 2056381T3
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- diazabiciclos
- diazabicyclo
- proline
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/48—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
INTERMEDIARIOS DIAZABICICLICO [2.2.1] HEPTANO SE PREPARAN A PARTIR DE 4-IDROXI-L- PROLINA EN UN PROCEDIMIENTO DE 5 ETAPAS, O A PARTIR DE HALO-4-HIDROXI-D-PROLINA, A TRAVES DE UN NUEVO INTERMEDIARIO DE 2-(C1-C6)ALKIL - 5 - SUSTITUIDO - 2,5 -DIAZABICICLO [2.2.1] HEPTANO. LOS DIAZABICICLOHEPTANOS SE USAN EN LA PREPARACION DE QUINOLONAS ANTIBIOTICAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35042389A | 1989-05-11 | 1989-05-11 | |
US07/423,063 US5036153A (en) | 1989-05-11 | 1989-10-18 | Preparation of 2,5-diazabicyclo[2.2.1]heptanes and intermediates |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2056381T3 true ES2056381T3 (es) | 1994-10-01 |
Family
ID=26996610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90304442T Expired - Lifetime ES2056381T3 (es) | 1989-05-11 | 1990-04-25 | Preparacion de intermedios diazabiciclos. |
Country Status (21)
Country | Link |
---|---|
US (1) | US5036153A (es) |
EP (1) | EP0397351B1 (es) |
JP (1) | JPH035482A (es) |
KR (1) | KR920003560B1 (es) |
CN (1) | CN1025852C (es) |
AT (1) | ATE108795T1 (es) |
AU (1) | AU637099B2 (es) |
CA (1) | CA2016343C (es) |
CZ (1) | CZ279947B6 (es) |
DE (1) | DE69010761T2 (es) |
DK (1) | DK0397351T3 (es) |
ES (1) | ES2056381T3 (es) |
FI (1) | FI96682C (es) |
HU (1) | HU206718B (es) |
IE (1) | IE64185B1 (es) |
IL (1) | IL94303A (es) |
NO (1) | NO902072L (es) |
NZ (1) | NZ233624A (es) |
PT (1) | PT93986B (es) |
RU (1) | RU2024524C1 (es) |
YU (1) | YU48131B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5196548A (en) * | 1989-05-11 | 1993-03-23 | Pfizer Inc. | Preparation of diazabicyclic Intermediates |
US5128483A (en) * | 1989-07-19 | 1992-07-07 | American Cyanamid Company | Dibromovinyl and acetylene-1-pyrrolidinecarboxylic acid intermediates |
DE4029054A1 (de) * | 1990-09-13 | 1992-03-19 | Bayer Ag | N-acylpyrrolidin-derivate |
US5254696A (en) * | 1990-09-13 | 1993-10-19 | Bayer Aktiengesellschaft | N-acylpyrrolidine derivatives |
AT403803B (de) | 1996-04-19 | 1998-05-25 | Sanochemia Ltd | Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln |
US6589978B2 (en) * | 2000-06-30 | 2003-07-08 | Hoffman-La Roche Inc. | 1-sulfonyl pyrrolidine derivatives |
JP4827154B2 (ja) * | 2001-07-25 | 2011-11-30 | 株式会社オーイズミ | 遊技装置 |
TW200303742A (en) * | 2001-11-21 | 2003-09-16 | Novartis Ag | Organic compounds |
JP4631262B2 (ja) * | 2003-10-07 | 2011-02-16 | 東レ・ファインケミカル株式会社 | (シス)−4−ヒドロキシプロリン誘導体の製造方法 |
JP2007244428A (ja) * | 2006-03-13 | 2007-09-27 | Olympia:Kk | メダル貸出機 |
JP4771416B2 (ja) * | 2006-03-22 | 2011-09-14 | サミー株式会社 | 遊技機 |
CN102180824B (zh) * | 2011-02-18 | 2012-11-14 | 华东理工大学 | 吡咯衍生物的制备方法 |
CN103755710B (zh) * | 2014-01-14 | 2015-08-12 | 昆明理工大学 | 一类2,5-二氮杂双环庚烷类化合物及其应用 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3083208A (en) * | 1961-05-11 | 1963-03-26 | Mead Johnson & Co | 1-acyl and 1-carbalkoxy-3-pyrrolidinols |
NL124628C (es) * | 1963-02-05 | |||
US3459768A (en) * | 1966-05-24 | 1969-08-05 | Richardson Merrell Inc | Pyrrolidine-2,2-dimethanols and methods of preparing the same |
US3905979A (en) * | 1974-05-09 | 1975-09-16 | Stanford Research Inst | Diazabicyclooctanes and diazabicycloheptanes |
US3947445A (en) * | 1974-05-09 | 1976-03-30 | Stanford Research Institute | Diazabicyclooctanes and diazabicycloheptanes |
HU184960B (en) * | 1981-07-20 | 1984-11-28 | Richter Gedeon Vegyeszet | Process for preparing new derivatives of 3,7-diazabicyclo/3.3.1/ nonane |
US4539411A (en) * | 1982-02-05 | 1985-09-03 | Hoffmann-La Roche Inc. | Rhodium complexes of chiral phosphines |
JPS60190760A (ja) * | 1984-03-09 | 1985-09-28 | Mitsubishi Chem Ind Ltd | ピロリジン誘導体及びその製造法 |
US4571396A (en) * | 1984-04-16 | 1986-02-18 | Warner-Lambert Company | Antibacterial agents |
IN166416B (es) * | 1985-09-18 | 1990-05-05 | Pfizer | |
JPS63162672A (ja) * | 1986-12-25 | 1988-07-06 | Ono Pharmaceut Co Ltd | 新規なプロリナ−ル誘導体、それらの製造方法およびそれらを含有する抗健忘症剤 |
US4923879A (en) * | 1987-07-31 | 1990-05-08 | Warner-Lambert Company | 1,8-Naphthyridines and their use as antibacterial agents |
GB8800694D0 (en) * | 1988-01-13 | 1988-02-10 | Pfizer Ltd | Antiarrhythmic agents |
-
1989
- 1989-10-18 US US07/423,063 patent/US5036153A/en not_active Expired - Lifetime
-
1990
- 1990-04-25 DE DE69010761T patent/DE69010761T2/de not_active Expired - Fee Related
- 1990-04-25 ES ES90304442T patent/ES2056381T3/es not_active Expired - Lifetime
- 1990-04-25 EP EP90304442A patent/EP0397351B1/en not_active Expired - Lifetime
- 1990-04-25 DK DK90304442.8T patent/DK0397351T3/da active
- 1990-04-25 AT AT90304442T patent/ATE108795T1/de not_active IP Right Cessation
- 1990-05-06 IL IL9430390A patent/IL94303A/en not_active IP Right Cessation
- 1990-05-08 CZ CS902279A patent/CZ279947B6/cs not_active IP Right Cessation
- 1990-05-09 PT PT93986A patent/PT93986B/pt not_active IP Right Cessation
- 1990-05-09 NZ NZ233624A patent/NZ233624A/en unknown
- 1990-05-09 CA CA002016343A patent/CA2016343C/en not_active Expired - Lifetime
- 1990-05-10 HU HU902994A patent/HU206718B/hu not_active IP Right Cessation
- 1990-05-10 NO NO90902072A patent/NO902072L/no unknown
- 1990-05-10 AU AU54908/90A patent/AU637099B2/en not_active Ceased
- 1990-05-10 CN CN90102798A patent/CN1025852C/zh not_active Expired - Lifetime
- 1990-05-10 KR KR1019900006578A patent/KR920003560B1/ko not_active IP Right Cessation
- 1990-05-10 YU YU91390A patent/YU48131B/sh unknown
- 1990-05-10 IE IE168990A patent/IE64185B1/en not_active IP Right Cessation
- 1990-05-10 RU SU904743987A patent/RU2024524C1/ru not_active IP Right Cessation
- 1990-05-10 FI FI902334A patent/FI96682C/fi active IP Right Grant
- 1990-05-11 JP JP2122831A patent/JPH035482A/ja active Pending
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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