ES2155517T3 - Derivados del acido n-acetil-neuraminico y procedimientos para su preparacion. - Google Patents

Derivados del acido n-acetil-neuraminico y procedimientos para su preparacion.

Info

Publication number
ES2155517T3
ES2155517T3 ES95904472T ES95904472T ES2155517T3 ES 2155517 T3 ES2155517 T3 ES 2155517T3 ES 95904472 T ES95904472 T ES 95904472T ES 95904472 T ES95904472 T ES 95904472T ES 2155517 T3 ES2155517 T3 ES 2155517T3
Authority
ES
Spain
Prior art keywords
acetyl
procedures
derivatives
preparation
neuraminic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95904472T
Other languages
English (en)
Inventor
Christopher Williamson
William James White
Vipulkumar Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biota Scientific Management Pty Ltd
Original Assignee
Biota Scientific Management Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scientific Management Pty Ltd filed Critical Biota Scientific Management Pty Ltd
Application granted granted Critical
Publication of ES2155517T3 publication Critical patent/ES2155517T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE PRESENTA UN ACIDO ACETAMIDO-2, 3, 4, 5 - TETRADEOXI 4 GUANIDINO - D - GLYCERO - D - GALACTO - NO - 2 - ENOPIRANOSONICO EN FORMA CRISTALINA, PARTICULARMENTE EN FORMA DE UN HIDRATO QUE EXISTE COMO CRISTALES QUE TIENEN UNA BAJA RELACION DE ASPECTO, O EN LA FORMA DE UN HIDRATO QUE EXISTE COMO CRISTALES QUE TIENEN UNA ALTA PROPORCION DE ASPECTO.
ES95904472T 1993-12-17 1994-12-15 Derivados del acido n-acetil-neuraminico y procedimientos para su preparacion. Expired - Lifetime ES2155517T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939325841A GB9325841D0 (en) 1993-12-17 1993-12-17 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2155517T3 true ES2155517T3 (es) 2001-05-16

Family

ID=10746778

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95904472T Expired - Lifetime ES2155517T3 (es) 1993-12-17 1994-12-15 Derivados del acido n-acetil-neuraminico y procedimientos para su preparacion.

Country Status (44)

Country Link
US (2) US6294572B1 (es)
EP (1) EP0734382B1 (es)
JP (1) JP3317972B2 (es)
KR (1) KR100403256B1 (es)
CN (2) CN1132829C (es)
AP (2) AP9600810A0 (es)
AT (1) ATE199255T1 (es)
BG (1) BG63338B1 (es)
BR (2) BR9408340A (es)
CA (1) CA2177990C (es)
CO (1) CO4340619A1 (es)
CZ (1) CZ289234B6 (es)
DE (1) DE69426726T2 (es)
DK (1) DK0734382T3 (es)
EE (1) EE03353B1 (es)
EG (1) EG20597A (es)
ES (1) ES2155517T3 (es)
FI (1) FI120453B (es)
GB (1) GB9325841D0 (es)
GR (1) GR3035681T3 (es)
HK (1) HK1014187A1 (es)
HR (1) HRP941001B1 (es)
HU (1) HU221971B1 (es)
IL (1) IL112011A (es)
IS (1) IS4240A (es)
MA (1) MA23396A1 (es)
MY (1) MY116221A (es)
NO (1) NO314759B1 (es)
NZ (1) NZ277789A (es)
OA (2) OA10325A (es)
PE (1) PE31095A1 (es)
PL (1) PL186384B1 (es)
PT (1) PT734382E (es)
RO (1) RO114792B1 (es)
RU (1) RU2134690C1 (es)
SA (1) SA94150417B1 (es)
SG (1) SG46669A1 (es)
SI (1) SI0734382T1 (es)
SK (1) SK282972B6 (es)
SV (1) SV1994000076A (es)
TW (1) TW452577B (es)
UA (1) UA46723C2 (es)
WO (1) WO1995016680A1 (es)
ZA (1) ZA9410003B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325841D0 (en) * 1993-12-17 1994-02-23 Glaxo Group Ltd Chemical compounds
US5866601A (en) * 1995-02-27 1999-02-02 Gilead Sciences, Inc. Carbocyclic compounds
DK0759917T3 (da) * 1995-02-27 2000-07-31 Gilead Sciences Inc Hidtil ukendte selektive inhibitorer af virale eller bakterielle neuraminidaser
US5763483A (en) * 1995-12-29 1998-06-09 Gilead Sciences, Inc. Carbocyclic compounds
US6340702B1 (en) 1996-07-22 2002-01-22 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
DE69709795T2 (de) * 1996-07-22 2002-09-26 Sankyo Co Neuraminsäuredervate, ihre Herstellung und medizinische Verwendung
US6451766B1 (en) 1996-07-22 2002-09-17 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
US6518438B2 (en) 1996-08-23 2003-02-11 Gilead Sciences, Inc. Preparation of cyclohexene carboxylate derivatives
US5859284A (en) * 1996-08-23 1999-01-12 Gilead Sciences, Inc. Preparation of carbocyclic compounds
US5994377A (en) * 1996-10-21 1999-11-30 Gilead Sciences, Inc. Piperidine compounds
US5886213A (en) * 1997-08-22 1999-03-23 Gilead Sciences, Inc. Preparation of carbocyclic compounds
TW477783B (en) * 1997-12-12 2002-03-01 Gilead Sciences Inc Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
TWI291462B (en) 2000-04-25 2007-12-21 Daiichi Sankyo Co Ltd Hydrate crystal of neuraminic acid compound
US20080063722A1 (en) * 2006-09-08 2008-03-13 Advanced Inhalation Research, Inc. Composition of a Spray-Dried Powder for Pulmonary Delivery of a Long Acting Neuraminidase Inhibitor (LANI)
EP2960237A1 (en) * 2011-12-16 2015-12-30 Daiichi Sankyo Company, Limited Method for producing neuraminic acid derivative
CN109232677B (zh) * 2018-10-18 2021-12-28 中国科学院合肥物质科学研究院 一种使n-乙酰神经氨酸水合物转化为n-乙酰神经氨酸的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP249A (en) * 1990-04-24 1993-03-17 Biota Scient Management Pty Ltd Anti-viral compounds.
AU659501B2 (en) * 1991-10-23 1995-05-18 Biota Scientific Management Pty Ltd Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of alpha-D-neuraminic acid
US5639786A (en) 1992-12-04 1997-06-17 Biota Scientific Management, Pty., Ltd. Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of α-D-neuraninic acid
GB9325841D0 (en) * 1993-12-17 1994-02-23 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
HRP941001A2 (en) 1997-06-30
DE69426726D1 (de) 2001-03-29
IS4240A (is) 1995-06-18
IL112011A0 (en) 1995-03-15
NO962545L (no) 1996-06-14
BG63338B1 (bg) 2001-10-31
KR100403256B1 (ko) 2004-04-30
SA94150417B1 (ar) 2005-12-18
HRP941001B1 (en) 2001-06-30
OA11275A (en) 2002-11-20
HK1014187A1 (en) 1999-09-24
AU1314495A (en) 1995-07-03
PL186384B1 (pl) 2004-01-30
SK282972B6 (sk) 2003-01-09
CN1132829C (zh) 2003-12-31
HU221971B1 (hu) 2003-03-28
IL112011A (en) 1998-08-16
SI0734382T1 (en) 2001-08-31
CN1502621A (zh) 2004-06-09
BR9408340A (pt) 1997-08-19
SV1994000076A (es) 1995-10-26
AP9400705A0 (en) 1995-01-31
PT734382E (pt) 2001-06-29
RO114792B1 (ro) 1999-07-30
BG100709A (bg) 1997-01-31
EP0734382A1 (en) 1996-10-02
US6294572B1 (en) 2001-09-25
US20020037865A1 (en) 2002-03-28
PL315055A1 (en) 1996-09-30
HUT74938A (en) 1997-03-28
PE31095A1 (es) 1995-10-18
NZ277789A (en) 1999-04-29
RU2134690C1 (ru) 1999-08-20
MY116221A (en) 2003-12-31
AP9600810A0 (en) 1996-07-31
FI962464A0 (fi) 1996-06-13
GR3035681T3 (en) 2001-06-29
CA2177990C (en) 2000-04-25
SG46669A1 (en) 1998-02-20
MA23396A1 (fr) 1995-07-01
FI120453B (fi) 2009-10-30
ZA9410003B (en) 1995-07-25
NO962545D0 (no) 1996-06-14
BR1100548KB1 (pt) 2011-11-01
NO314759B1 (no) 2003-05-19
CO4340619A1 (es) 1996-07-30
EG20597A (en) 1999-09-30
UA46723C2 (uk) 2002-06-17
DE69426726T2 (de) 2001-06-21
ATE199255T1 (de) 2001-03-15
SK78596A3 (en) 1997-03-05
TW452577B (en) 2001-09-01
EP0734382B1 (en) 2001-02-21
GB9325841D0 (en) 1994-02-23
DK0734382T3 (da) 2001-03-19
FI962464A (fi) 1996-06-13
OA10325A (en) 1997-10-07
JP3317972B2 (ja) 2002-08-26
CZ169396A3 (en) 1996-11-13
JPH09506601A (ja) 1997-06-30
CZ289234B6 (cs) 2001-12-12
AU689185B2 (en) 1998-03-26
HU9601642D0 (en) 1996-08-28
EE03353B1 (et) 2001-02-15
AP541A (en) 1996-10-01
WO1995016680A1 (en) 1995-06-22
CA2177990A1 (en) 1995-06-22
CN1142820A (zh) 1997-02-12

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