FR2622798B1 - Forme d'apport dose et dispositif osmotique d'administration d'un medicament pour le traitement de maladies cardio-vasculaires - Google Patents
Forme d'apport dose et dispositif osmotique d'administration d'un medicament pour le traitement de maladies cardio-vasculairesInfo
- Publication number
- FR2622798B1 FR2622798B1 FR8812738A FR8812738A FR2622798B1 FR 2622798 B1 FR2622798 B1 FR 2622798B1 FR 8812738 A FR8812738 A FR 8812738A FR 8812738 A FR8812738 A FR 8812738A FR 2622798 B1 FR2622798 B1 FR 2622798B1
- Authority
- FR
- France
- Prior art keywords
- treatment
- dosage form
- delivery device
- cardiovascular diseases
- osmotic delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000024172 Cardiovascular disease Diseases 0.000 title 1
- 239000002552 dosage form Substances 0.000 title 1
- 230000003204 osmotic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/104,006 US4816263A (en) | 1987-10-02 | 1987-10-02 | Dosage form for treating cardiovascular diseases comprising isradipine |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2622798A1 FR2622798A1 (fr) | 1989-05-12 |
FR2622798B1 true FR2622798B1 (fr) | 1993-10-15 |
Family
ID=22298196
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8812738A Expired - Lifetime FR2622798B1 (fr) | 1987-10-02 | 1988-09-29 | Forme d'apport dose et dispositif osmotique d'administration d'un medicament pour le traitement de maladies cardio-vasculaires |
Country Status (22)
Country | Link |
---|---|
US (1) | US4816263A (fr) |
JP (1) | JP2590235B2 (fr) |
KR (1) | KR950010151B1 (fr) |
AT (1) | AT402689B (fr) |
AU (1) | AU615215B2 (fr) |
BE (1) | BE1001101A5 (fr) |
CA (1) | CA1317550C (fr) |
CH (1) | CH677609A5 (fr) |
DE (1) | DE3833282C2 (fr) |
DK (1) | DK175564B1 (fr) |
ES (1) | ES2011120A6 (fr) |
FI (1) | FI92554C (fr) |
FR (1) | FR2622798B1 (fr) |
GB (1) | GB2210266B (fr) |
IE (1) | IE61862B1 (fr) |
IT (1) | IT1234215B (fr) |
LU (1) | LU87351A1 (fr) |
NL (1) | NL194748C (fr) |
NO (1) | NO176466C (fr) |
PT (1) | PT88618B (fr) |
SE (1) | SE503471C2 (fr) |
ZA (1) | ZA887362B (fr) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4946687A (en) * | 1987-10-02 | 1990-08-07 | Alza Corporation | Dosage form for treating cardiovascular diseases |
US4816263A (en) * | 1987-10-02 | 1989-03-28 | Alza Corporation | Dosage form for treating cardiovascular diseases comprising isradipine |
US5208037A (en) * | 1991-04-22 | 1993-05-04 | Alza Corporation | Dosage forms comprising polymers comprising different molecular weights |
US6124355A (en) * | 1995-05-22 | 2000-09-26 | Guittard; George V. | Oxybutynin therapy |
US6262115B1 (en) * | 1995-05-22 | 2001-07-17 | Alza Coporation | Method for the management of incontinence |
US5674895A (en) * | 1995-05-22 | 1997-10-07 | Alza Corporation | Dosage form comprising oxybutynin |
US5912268A (en) * | 1995-05-22 | 1999-06-15 | Alza Corporation | Dosage form and method for treating incontinence |
US20040062799A1 (en) * | 1997-09-29 | 2004-04-01 | Ayer Atul D. | Therapeutic composition and delivery system for administering drug |
DE19747261A1 (de) * | 1997-10-25 | 1999-04-29 | Bayer Ag | Osmotisches Arzneimittelfreisetzungssystem |
AR018321A1 (es) * | 1998-03-26 | 2001-11-14 | Alza Corp | Una forma de dosificacion de liberacion prolongada que comprende oxibutinina y los usos de la oxibutinina y de la forma de dosificacion de liberacionprolongada. |
US20010038855A1 (en) * | 1998-06-05 | 2001-11-08 | Desjardin Michael A. | Dosage form for administering prescribed dose |
US6238697B1 (en) | 1998-12-21 | 2001-05-29 | Pharmalogix, Inc. | Methods and formulations for making bupropion hydrochloride tablets using direct compression |
JP4216713B2 (ja) * | 2001-06-11 | 2009-01-28 | ゼノポート,インコーポレイティド | Gaba類似体のプロドラッグ、組成物およびその使用 |
US7232924B2 (en) * | 2001-06-11 | 2007-06-19 | Xenoport, Inc. | Methods for synthesis of acyloxyalkyl derivatives of GABA analogs |
US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
WO2002100344A2 (fr) * | 2001-06-11 | 2002-12-19 | Xenoport, Inc. | Conjugues d'amino acides permettant d'obtenir des concentrations systemiques soutenues d'analogues du gaba |
US6524618B1 (en) | 2001-06-12 | 2003-02-25 | Vijai Kumar | Directly compressible extended-release matrix formulation for metformin hydrochloride |
WO2004052841A1 (fr) | 2002-12-06 | 2004-06-24 | Xenoport, Inc. | Promedicamemts de carbidopa et leurs utilisations |
WO2004053192A1 (fr) * | 2002-12-11 | 2004-06-24 | Xenoport, Inc. | Formes posologiques administrees oralement de promedicaments analogues de gaba fondu a toxicite reduite |
AU2004227995B2 (en) * | 2003-03-31 | 2010-06-03 | Xenoport, Inc. | Treating or preventing hot flashes using prodrugs of GABA analogs |
US7109239B2 (en) | 2003-08-20 | 2006-09-19 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use |
EP2354120A1 (fr) | 2003-08-20 | 2011-08-10 | XenoPort, Inc. | Synthèse de promédicaments a base de carbamate d'acyloxyalkyle et leurs intermédiaires |
MXPA06002731A (es) * | 2003-09-11 | 2006-06-05 | Xenoport Inc | Tratamiento y/o prevencion de incontinencia urinaria utilizando profarmacos de analogos de gaba. |
US8114909B2 (en) * | 2003-09-17 | 2012-02-14 | Xenoport, Inc. | Treating or preventing restless legs syndrome using prodrugs of GABA analogs |
US20060128676A1 (en) * | 2004-07-13 | 2006-06-15 | Pharmacofore, Inc. | Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain |
US7566738B2 (en) * | 2004-11-03 | 2009-07-28 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use |
WO2006050472A2 (fr) * | 2004-11-03 | 2006-05-11 | Xenoport, Inc. | Prodrogues d'acyloxyalkyl carbamate, et leurs procedes de synthese et d'utilisation |
US8795725B2 (en) | 2004-11-04 | 2014-08-05 | Xenoport, Inc. | GABA analog prodrug sustained release oral dosage forms |
JP4938771B2 (ja) | 2005-06-20 | 2012-05-23 | ゼノポート,インコーポレーテッド | トラネキサム酸のカルバミン酸アシルオキシアルキルプロドラッグ、合成法、および使用 |
ZA200711123B (en) | 2005-06-27 | 2009-08-26 | Biovail Lab Int Srl | Modified-release formulations of a bupropion salt |
EP1928450A2 (fr) * | 2005-08-26 | 2008-06-11 | Xenoport, Inc. | Traitement de l'ejaculation prematuree utilisant des prodrogues de gabapentine et de pregabaline |
US20070128282A1 (en) * | 2005-12-02 | 2007-06-07 | Patel Hasmukh B | Oral osmotic drug delivery system |
ES2456674T3 (es) | 2006-05-26 | 2014-04-23 | Signature Therapeutics, Inc. | Liberación controlada de opioides fenólicos |
WO2008033572A1 (fr) * | 2006-09-15 | 2008-03-20 | Xenoport, Inc. | Promédicaments à base de carbamate d'acyloxyalkyle, procédés de synthèse et utilisation |
AU2007332904A1 (en) * | 2006-12-08 | 2008-06-19 | Xenoport, Inc. | Use of prodrugs of GABA analogs for treating diseases |
US7714201B2 (en) * | 2006-12-22 | 2010-05-11 | Monsanto Technology Llc | Cotton variety 781000G |
US7419684B2 (en) * | 2006-12-22 | 2008-09-02 | Reliant Pharmaceuticals, Inc. | System and method for manufacturing oral osmotic drug delivery devices, and methods of administering same |
US20080249141A1 (en) * | 2007-04-06 | 2008-10-09 | Palepu Nageswara R | Co-therapy with and combinations of statins and 1,4-dihydropyridine-3,5-dicarboxydiesters |
US20110060040A1 (en) * | 2009-09-04 | 2011-03-10 | Xenoport, Inc. | Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid |
EP2621282B1 (fr) | 2010-09-28 | 2020-04-15 | The Regents of The University of California | Agonistes de gaba dans le traitement de troubles associés au syndrome métabolique et combinaisons de gaba dans le traitement ou la prophylaxie du diabète de type i |
CN102349880B (zh) * | 2011-10-12 | 2015-07-22 | 合肥华方医药科技有限公司 | 伊拉地平控释片及其制备方法 |
CN105030726A (zh) * | 2015-08-30 | 2015-11-11 | 四川百利药业有限责任公司 | 一种伊拉地平胶囊的制备方法 |
GB2556817B (en) | 2015-10-01 | 2019-11-06 | Elysium Therapeutics Inc | Polysubunit opioid prodrugs resistant to overdose and abuse |
US10335406B2 (en) | 2015-10-01 | 2019-07-02 | Elysium Therapeutics, Inc. | Opioid compositions resistant to overdose and abuse |
CA3056239C (fr) | 2017-03-17 | 2023-09-12 | Elysium Therapeutics, Inc. | Promedicaments d'opioides a sous-unites multiples resistants aux surdoses et aux abus |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) * | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
GB1478759A (en) * | 1974-11-18 | 1977-07-06 | Alza Corp | Process for forming outlet passageways in pills using a laser |
US4063064A (en) * | 1976-02-23 | 1977-12-13 | Coherent Radiation | Apparatus for tracking moving workpiece by a laser beam |
CH639659A5 (de) * | 1978-12-18 | 1983-11-30 | Sandoz Ag | Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. |
US4285987A (en) * | 1978-10-23 | 1981-08-25 | Alza Corporation | Process for manufacturing device with dispersion zone |
US4200098A (en) * | 1978-10-23 | 1980-04-29 | Alza Corporation | Osmotic system with distribution zone for dispensing beneficial agent |
US4327725A (en) * | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
NZ206600A (en) * | 1983-05-11 | 1987-01-23 | Alza Corp | Osmotic drug delivery device |
US4612008A (en) * | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
NL194389C (nl) * | 1984-06-14 | 2002-03-04 | Novartis Ag | Werkwijze voor het bereiden van een vaste dispersie van een farmaceutisch actief middel dat een lage oplosbaarheid in water heeft, in een vaste matrix van een in water oplosbaar polyalkyleenglycol als drager. |
US4627851A (en) * | 1984-10-26 | 1986-12-09 | Alza Corporation | Colonic-therapeutic delivery system |
US4624847A (en) * | 1985-04-22 | 1986-11-25 | Alza Corporation | Drug delivery device for programmed delivery of beneficial drug |
GB2181053B (en) * | 1985-10-01 | 1990-05-23 | Sandoz Ltd | Pharmaceutical formulations with controlled release of the active substance |
US4723957A (en) * | 1986-02-07 | 1988-02-09 | Alza Corp. | System for delivering drug with enhanced bioacceptability |
US4753802A (en) * | 1986-03-19 | 1988-06-28 | Alza Corporation | Verapamil dosage form |
AU2152888A (en) * | 1987-08-25 | 1989-03-02 | Cerra Metal Works Pty. Ltd. | Masonry tie |
US4816263A (en) * | 1987-10-02 | 1989-03-28 | Alza Corporation | Dosage form for treating cardiovascular diseases comprising isradipine |
-
1987
- 1987-10-02 US US07/104,006 patent/US4816263A/en not_active Expired - Lifetime
-
1988
- 1988-09-27 BE BE8801099A patent/BE1001101A5/fr not_active IP Right Cessation
- 1988-09-27 NO NO884259A patent/NO176466C/no not_active IP Right Cessation
- 1988-09-28 KR KR1019880012536A patent/KR950010151B1/ko not_active IP Right Cessation
- 1988-09-28 LU LU87351A patent/LU87351A1/fr unknown
- 1988-09-29 DK DK198805450A patent/DK175564B1/da active
- 1988-09-29 NL NL8802401A patent/NL194748C/nl not_active IP Right Cessation
- 1988-09-29 PT PT88618A patent/PT88618B/pt not_active IP Right Cessation
- 1988-09-29 FR FR8812738A patent/FR2622798B1/fr not_active Expired - Lifetime
- 1988-09-29 AU AU22938/88A patent/AU615215B2/en not_active Expired
- 1988-09-29 GB GB8822852A patent/GB2210266B/en not_active Expired - Lifetime
- 1988-09-30 JP JP63247298A patent/JP2590235B2/ja not_active Expired - Lifetime
- 1988-09-30 DE DE3833282A patent/DE3833282C2/de not_active Expired - Lifetime
- 1988-09-30 AT AT0242288A patent/AT402689B/de not_active IP Right Cessation
- 1988-09-30 IT IT8867880A patent/IT1234215B/it active
- 1988-09-30 CH CH3642/88A patent/CH677609A5/de not_active IP Right Cessation
- 1988-09-30 SE SE8803486A patent/SE503471C2/sv not_active IP Right Cessation
- 1988-09-30 IE IE296088A patent/IE61862B1/en not_active IP Right Cessation
- 1988-09-30 ZA ZA887362A patent/ZA887362B/xx unknown
- 1988-09-30 FI FI884526A patent/FI92554C/fi not_active IP Right Cessation
- 1988-09-30 ES ES8802980A patent/ES2011120A6/es not_active Expired
- 1988-09-30 CA CA000578959A patent/CA1317550C/fr not_active Expired - Lifetime
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