ES2153383T3 - Haptenos, trazadores, inmunogenos y anticuerpos para acidos 3-fenileno-1-adamantanoaceticos. - Google Patents

Haptenos, trazadores, inmunogenos y anticuerpos para acidos 3-fenileno-1-adamantanoaceticos.

Info

Publication number
ES2153383T3
ES2153383T3 ES93914457T ES93914457T ES2153383T3 ES 2153383 T3 ES2153383 T3 ES 2153383T3 ES 93914457 T ES93914457 T ES 93914457T ES 93914457 T ES93914457 T ES 93914457T ES 2153383 T3 ES2153383 T3 ES 2153383T3
Authority
ES
Spain
Prior art keywords
conjugates
immunogens
intermediates
haptens
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93914457T
Other languages
English (en)
Inventor
Phillip G Mattingly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2153383T3 publication Critical patent/ES2153383T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/90—Xanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

NUEVOS INTERMEDIARIOS Y CONJUGADOS RELACIONADOS DE HAPTENO UNIDOS BASADOS EN ACIDO 3-FENIL-1-ADAMANTANEACETICO, ASI COMO METODOS PARA FABRICAR Y UTILIZAR TALES CONJUGADOS. LOS HAPTENOS BASADOS EN LA ANTERIOR ESTRUCTURA CENTRAL PUEDEN SER SUSTITUIDOS EN CUALQUIER POSICION EN EL ANILLO DE FENILO, ESPECIALMENTE EN LA POSICION PARA. SE DESCRIBE LA UTILIZACION DE INTERMEDIARIOS UNIDOS, SUSTANCIAS INMUNOGENAS, INDICADORES RADIOACTIVOS, SOPORTES SOLIDOS Y OLIGONUCLEOTIDOS ETIQUETADOS; TAMBIEN METODOS PARA UTILIZAR LOS INTERMEDIARIOS PARA PREPARAR LOS CONJUGADOS, METODOS DE UTILIZACION DE LOS CONJUGADOS PARA FABRICAR Y PURIFICAR ANTICUERPOS, ASI COMO INDICADORES RADIOACTIVOS DE ENSAYO, Y ENSAYO DE HIBRIDIZACION DE ACIDO NUCLEICO. TAMBIEN SE DESCRIBEN CONJUNTOS QUE CONTIENEN OLIGONUCLEOTIDOS CON HAPTENO Y CONJUGADOS ANTI-HAPTENO.
ES93914457T 1993-06-10 1993-06-10 Haptenos, trazadores, inmunogenos y anticuerpos para acidos 3-fenileno-1-adamantanoaceticos. Expired - Lifetime ES2153383T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1993/005534 WO1994029329A1 (en) 1993-06-10 1993-06-10 Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adamantaneacetic acids

Publications (1)

Publication Number Publication Date
ES2153383T3 true ES2153383T3 (es) 2001-03-01

Family

ID=22236683

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93914457T Expired - Lifetime ES2153383T3 (es) 1993-06-10 1993-06-10 Haptenos, trazadores, inmunogenos y anticuerpos para acidos 3-fenileno-1-adamantanoaceticos.

Country Status (7)

Country Link
EP (1) EP0702689B1 (es)
JP (1) JPH08511516A (es)
AT (1) ATE196911T1 (es)
AU (1) AU4411093A (es)
DE (1) DE69329557T2 (es)
ES (1) ES2153383T3 (es)
WO (1) WO1994029329A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999049831A2 (en) * 1998-03-28 1999-10-07 Martin Vladimir V Amplified fluorescent materials and uses thereof
CZ2014527A3 (cs) 2014-08-05 2016-02-17 Ústav Organické Chemie A Biochemie Akademie Věd Čr, V.V.I. Způsob detekce aktivní formy analytů ve vzorku a stanovení schopnosti dalších látek vázat se do aktivních míst těchto analytů
WO2018013999A1 (en) 2016-07-15 2018-01-18 Am Chemicals Llc Non-nucleosidic solid supports and phosphoramidite building blocks for oligonucleotide synthesis
WO2019018185A1 (en) 2017-07-15 2019-01-24 Arisan Therapeutics Inc. ENANTIOMERICALLY PURE ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTIONS
CN114249705A (zh) * 2021-12-24 2022-03-29 苏州快捷康生物技术有限公司 一种赤霉素半抗原与抗原的制备及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3816509A (en) * 1969-07-02 1974-06-11 Searle & Co Esters of 3-phenyladamantane-1-carboxylic acid
US4680275A (en) * 1985-02-11 1987-07-14 Becton, Dickinson And Company Homogeneous fluorescence immunoassay using a light absorbing material
DE3618407A1 (de) * 1986-05-31 1987-12-03 Victor Dipl Chem Dr Med Brantl Pharmakologisch aktive peptide

Also Published As

Publication number Publication date
EP0702689A1 (en) 1996-03-27
DE69329557T2 (de) 2001-05-31
EP0702689B1 (en) 2000-10-11
DE69329557D1 (de) 2000-11-16
WO1994029329A1 (en) 1994-12-22
JPH08511516A (ja) 1996-12-03
AU4411093A (en) 1995-01-03
ATE196911T1 (de) 2000-10-15
EP0702689A4 (en) 1997-10-22

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